CAS 49608-51-7

4,5-Dihydro-2-(2-hydroxyphenyl)-4-thiazolecarboxylic acid

Description:

4,5-Dihydro-2-(2-hydroxyphenyl)-4-thiazolecarboxylic acid, with the CAS number 49608-51-7, is a chemical compound characterized by its thiazole ring structure, which is a five-membered heterocyclic ring containing sulfur and nitrogen. This compound features a carboxylic acid functional group, contributing to its acidity and potential reactivity. The presence of a hydroxyl group on the phenyl ring enhances its solubility in polar solvents and may influence its biological activity. The thiazole moiety is known for its role in various pharmacological applications, including antimicrobial and anti-inflammatory properties. Additionally, the compound's structural features suggest potential interactions with biological targets, making it of interest in medicinal chemistry. Its synthesis typically involves multi-step organic reactions, and it may be utilized in research settings to explore its chemical behavior and potential therapeutic uses. Overall, 4,5-Dihydro-2-(2-hydroxyphenyl)-4-thiazolecarboxylic acid represents a versatile compound with significant implications in both chemical and biological research.

Formula: C₁₀H₉NO₃S

InChI: InChI=1/C10H9NO3S/c12-8-4-2-1-3-6(8)9-11-7(5-15-9)10(13)14/h1-4,7,11H,5H2,(H,13,14)/b9-6+

InChI key: InChIKey=CECDPVOEINSAQG-UHFFFAOYSA-N

SMILES: OC1=C(C=CC=C1)C2=NC(C(O)=O)CS2

Synonyms:

• 2-(2-Hydroxyphenyl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid
• Dihydroeruginoic acid
• 4-Thiazolecarboxylic acid, 4,5-dihydro-2-(2-hydroxyphenyl)-
• 2-Thiazoline-4-carboxylic acid, 2-(o-hydroxyphenyl)-
• 4,5-Dihydro-2-(2-hydroxyphenyl)-4-thiazolecarboxylic acid

Dihydroaeruginoic Acid

CAS: 49608-51-7

Dihydroaeruginoic acid, an antibiotic sourced originally from P. fluorescens, exhibits antimicrobial efficacy in disc assays against diverse pathogens, including R. solani, P. ultimum, B. cinerea, S. rolfsii, C. gloeosporioides, F. oxysporum, and S. tritici fungi, along with B. subtilis, E. herbicola, and S. albus bacteria, at a concentration of 200 μg/disc.

Formula: C₁₀H₉NO₃S

Color and Shape: Solid

Molecular weight: 223.25

Ref: TM-TN7553

2-​(2-​Hydroxyphenyl)​-​4,​5-​dihydro-​1,​3-​thiazole-​4-​carboxylic Acid

Controlled Product

CAS: 49608-51-7

Applications 2-​(2-​Hydroxyphenyl)​-​4,​5-​dihydro-​1,​3-​thiazole-​4-​carboxylic Acid is an intermediate in synthesizing Pyochelin I and Pyochelin II (P840365). They are two major siderophores produced and secreted by Pseudomonas aeruginosa PAO1 to assimilate iron. It also has triphenyltin (T809350) decomposition capacity.
References Braud, A., et al.: J. Bacteriol., 191, 3517 (2009); Sun, G., et al.: Appl. Environ. Microb., 72, 7264 (2006)

Formula: C₁₀H₉NO₃S

Color and Shape: Neat

Molecular weight: 223.25

Ref: TR-H947113

2-(2-Hydroxyphenyl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid

CAS: 49608-51-7

2-(2-Hydroxyphenyl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid is a versatile compound with various applications in the field of research and chemical synthesis. It is commonly used as a building block for the synthesis of other compounds, such as medoxomil, coumarins, enalaprilat, thymidylate, dopamine derivatives, and more.

Formula: C₁₀H₉NO₃S

Purity: Min. 95%

Molecular weight: 223.25 g/mol

Ref: 3D-ZBA60851