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CAS 496835-35-9

:

Aildenafil

Description:
Aildenafil, with the CAS number 496835-35-9, is a synthetic compound that belongs to the class of phosphodiesterase type 5 (PDE5) inhibitors. It is structurally related to sildenafil, a well-known medication used to treat erectile dysfunction and pulmonary arterial hypertension. Aildenafil functions by enhancing the effects of nitric oxide, leading to increased blood flow to specific areas of the body, particularly the penis, thereby facilitating erection in response to sexual stimulation. The compound is characterized by its ability to selectively inhibit the PDE5 enzyme, which is responsible for the degradation of cyclic guanosine monophosphate (cGMP), a molecule that plays a crucial role in vasodilation. Aildenafil is typically administered orally and has a pharmacokinetic profile that allows for relatively rapid absorption and onset of action. While it shares similar therapeutic effects with sildenafil, its specific efficacy, safety profile, and potential side effects may differ, necessitating further research and clinical evaluation. As with any medication, it is important to use aildenafil under medical supervision to ensure safety and effectiveness.
Formula:C23H32N6O4S
InChI:InChI=1/C23H32N6O4S/c1-6-8-18-20-21(28(5)27-18)23(30)26-22(25-20)17-11-16(9-10-19(17)33-7-2)34(31,32)29-12-14(3)24-15(4)13-29/h9-11,14-15,24H,6-8,12-13H2,1-5H3,(H,25,26,30)/t14-,15+
InChI key:InChIKey=NFSWSZIPXJAYLR-GASCZTMLNA-N
SMILES:C(CC)C=1C2=C(C(=O)N=C(N2)C3=C(OCC)C=CC(S(=O)(=O)N4C[C@@H](C)N[C@@H](C)C4)=C3)N(C)N1
Synonyms:
  • 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-[5-[[(3R,5S)-3,5-dimethyl-1-piperazinyl]sulfonyl]-2-ethoxyphenyl]-1,6-dihydro-1-methyl-3-propyl-, rel-
  • Aildenafil
  • Methisosildenafil
  • rel-5-[5-[[(3R,5S)-3,5-Dimethyl-1-piperazinyl]sulfonyl]-2-ethoxyphenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one
  • Piperazine, 1-[[3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-3,5-dimethyl-, (3R,5S)-rel-
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Found 4 products.
  • Dimethyl Sildenafil
    TLC
    + Info

    Dimethyl Sildenafil

    CAS:
    Formula:C23H32N6O4S
    Color and Shape:White To Off-White Solid
    Molecular weight:488.61

    Ref: 4Z-S-0612

    5mg
    To inquire
    10mg
    508.00€
    25mg
    825.00€
    50mg
    1,153.00€
    100mg
    To inquire
  • Dimethyl Sildenafil-d5
    TLC
    + Info

    Dimethyl Sildenafil-d5

    CAS:
    Formula:C23H27D5N6O4S
    Molecular weight:493.64

    Ref: 4Z-S-0698

    5mg
    To inquire
    10mg
    1,456.00€
    25mg
    2,670.00€
    50mg
    4,368.00€
    100mg
    To inquire
  • Methisosildenafil
    TRC
    + Info

    Methisosildenafil

    Controlled Product
    CAS:
    <p>Applications A new Sildenafil (S435000) analogue detected as food adulterant.<br>References Gratz, S., et al.: J. Pharm. Biomed. Anal., 36, 525 (2004), Lai, K., et al.: J. Food Drug Anal., 14, 19 (2006), Oh, S., et al.: J. Toxicol. Environ. Health, 69, 1951 (2006),<br></p>
    Formula:C23H32N6O4S
    Color and Shape:White To Off-White
    Molecular weight:488.60

    Ref: TR-M225935

    5mg
    191.00€
    10mg
    348.00€
    50mg
    1,507.00€
  • Methisosildenafil
    Biosynth
    + Info

    Methisosildenafil

    CAS:
    Methisosildenafil is a chemical compound that belongs to the group of phosphodiesterase type-5 inhibitors. It is an analog of sildenafil and is used for the treatment of erectile dysfunction (ED). Methisosildenafil has been shown to be effective in animal models of pulmonary hypertension. It also inhibits the production of myeloid-derived suppressor cells, which are responsible for suppressing the immune system. Methisosildenafil has been found to be safe and well-tolerated for use as a pharmaceutical preparation in humans.
    Formula:C23H32N6O4S
    Purity:Min. 95%
    Molecular weight:488.6 g/mol

    Ref: 3D-WUA83535

    50mg
    991.00€
    100mg
    1,300.00€