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CAS 49697-38-3

:

Rimexolone

Description:
Rimexolone is a synthetic corticosteroid primarily used for its anti-inflammatory properties, particularly in the treatment of ocular conditions such as allergic conjunctivitis and post-operative inflammation. It is characterized by its ability to inhibit the release of inflammatory mediators, thereby reducing redness, swelling, and discomfort in the eye. Rimexolone is typically formulated as an ophthalmic suspension, allowing for direct application to the affected area. Its mechanism of action involves binding to glucocorticoid receptors, leading to the modulation of gene expression and subsequent reduction of inflammation. The substance is known for its relatively low systemic absorption when administered topically, which minimizes potential side effects associated with systemic corticosteroids. Rimexolone is generally well-tolerated, but like all corticosteroids, it may carry risks of increased intraocular pressure and potential for cataract formation with prolonged use. Overall, it serves as an effective therapeutic option in managing inflammatory eye conditions while requiring careful monitoring during treatment.
Formula:C24H34O3
InChI:InChI=1/C23H32O4/c1-13-10-17-16-7-6-14-11-15(24)8-9-21(14,2)19(16)18(25)12-22(17,3)23(13,4)20(26)27-5/h8-9,11,13,16-19,25H,6-7,10,12H2,1-5H3/t13-,16+,17+,18+,19-,21+,22+,23-/m1/s1
InChI key:InChIKey=QTTRZHGPGKRAFB-OOKHYKNYSA-N
SMILES:C[C@@]12[C@]([C@]3([C@]([C@@H](O)C1)([C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H])(C[C@@H](C)[C@@]2(C(CC)=O)C)[H]
Synonyms:
  • (10R,11S,13S,16R,17S)-11-hydroxy-10,13,16,17-tetramethyl-17-propanoyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)
  • (11beta,16alpha,17beta)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one
  • (11β,16α,17β)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one
  • 11beta-Hydroxy-16alpha,17,21-trimethyl-1,4-pregnadien-3,20-dion
  • 11beta-Hydroxy-16alpha,17alpha-dimethyl-17-propionylandrosta-1,4-dien-3-one
  • 11β-Hydroxy-16α,17,21-trimethylpregna-1,4-diene-3,20-dione
  • 11β-Hydroxy-16α,17α,21-trimethyl-5α-pregna-1,4-diene-3,20-dione
  • Al 02178
  • Androsta-1,4-dien-3-one, 11-hydroxy-16,17-dimethyl-17-(1-oxopropyl)-, (11beta,16alpha,17beta)-
  • Androsta-1,4-dien-3-one, 11-hydroxy-16,17-dimethyl-17-(1-oxopropyl)-, (11β,16α,17β)-
  • See more synonyms
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Found 4 products.
  • CymitQuimica logo
    USP
    + Info

    Rimexolone

    CAS:
    Adrenal cortical hormones and their derivatives nesoi
    Formula:C24H34O3
    Color and Shape:Powder
    Molecular weight:370.25079

    Ref: 45-1604600

  • Rimexolone
    Targetmol
    + Info

    Rimexolone

    CAS:
    Rimexolone is a glucocorticoid steroid used to treat inflammation in the eye.
    Formula:C24H34O3
    Color and Shape:Solid
    Molecular weight:370.52

    Ref: TM-T34328

  • Rimexolone
    TRC
    + Info

    Rimexolone

    Controlled Product
    CAS:
    Formula:C24H34O3
    Color and Shape:Neat
    Molecular weight:370.52

    Ref: TR-R422500

    100mg
    10,511.00€
  • (11b,16a,17b)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one
    Biosynth
    + Info

    (11b,16a,17b)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one

    Controlled Product
    CAS:
    (11b,16a,17b)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one is a biocompatible polymer with a statistically significant toxicity profile. It has been shown to inhibit the activity of Jak1 and may be useful in the treatment of infectious diseases. This polymer has been used in experimental models for the study of infectious diseases like HIV and tuberculosis. The polymer was also found to be an effective inhibitor of benzalkonium chloride-, antibiotic-, and eye disorders; however, it did not show any efficacy against autoimmune diseases or diabetic neuropathy.
    Formula:C24H34O3
    Purity:Min. 95%
    Molecular weight:370.52 g/mol

    Ref: 3D-FR27734

    50mg
    798.00€
    100mg
    931.00€