CAS 497-72-3

(2R,3S,7R,9S,10S,11R)-10-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-me thyl-oxan-2-yl]oxy-2-ethyl-3-hydroxy-3,7,9,11-tetramethyl-1-oxacyclodo dec-4-ene-6,12-dione

Description:

The chemical substance with the name "(2R,3S,7R,9S,10S,11R)-10-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyl-oxan-2-yl]oxy-2-ethyl-3-hydroxy-3,7,9,11-tetramethyl-1-oxacyclododec-4-ene-6,12-dione" and CAS number "497-72-3" is known as the antibiotic compound Erythromycin A. It is a macrolide antibiotic that exhibits a broad spectrum of antibacterial activity, particularly against Gram-positive bacteria and some Gram-negative bacteria. Erythromycin A is characterized by its complex polycyclic structure, which includes a large lactone ring and multiple stereocenters, contributing to its biological activity. The presence of hydroxyl and dimethylamino groups enhances its solubility and interaction with bacterial ribosomes, inhibiting protein synthesis. This compound is commonly used in clinical settings to treat various infections, including respiratory tract infections, skin infections, and sexually transmitted diseases. Its pharmacokinetics involve oral absorption, metabolism in the liver, and excretion primarily through bile. Erythromycin A is also known for its potential side effects, including gastrointestinal disturbances and interactions with other medications.

Formula: C₂₅H₄₃NO₇

InChI: InChI=1/C25H43NO7/c1-9-20-25(6,30)11-10-19(27)14(2)12-15(3)22(17(5)23(29)32-20)33-24-21(28)18(26(7)8)13-16(4)31-24/h10-11,14-18,20-22,24,28,30H,9,12-13H2,1-8H3/b11-10+/t14-,15+,16-,17-,18+,20-,21-,22+,24+,25+/m1/s1

Synonyms:

• Oxacyclododec-9-ene-2,8-dione, 12-ethyl-11-hydroxy-3,5,7,11-tetramethyl-4-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (3R,4S,5S,7R,9E,11S,12R)-
• vinomycin
• (2R,3S,7R,9S,10S,11R)-10-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-me thyl-oxan-2-yl]oxy-2-ethyl-3-hydroxy-3,7,9,11-tetramethyl-1-oxacyclodo dec-4-ene-6,12-dione
• methymycin
• Oxacyclododec-9-ene-2,8-dione,12-ethyl-11-hydroxy-3,5,7,11-tetramethyl-4-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]-,(3R,4S,5S,7R,9E,11S,12R)-
• (2R,3S,7R,9S,10S,11R)-10-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-me thyl-oxan-2-yl]oxy-2-ethyl-3-
• 497-72-3
• (3R,4S,5S,7R,9E,11S,12R)-12-Ethyl-11-hydroxy-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside

Methymycin

CAS: 497-72-3

Methymycin is a macrolide antibiotic with activity against Gram-positive bacteria and some Gram-negative bacteria.

Formula: C₂₅H₄₃NO₇

Color and Shape: Solid

Molecular weight: 469.611

Ref: TM-TN9958