CAS 497-76-7

Arbutin

Description:

Arbutin, with the CAS number 497-76-7, is a naturally occurring glycosylated hydroquinone, primarily found in the leaves of various plants, such as bearberry, blueberry, and cranberry. It is characterized by its chemical formula C12H16O7 and a molecular weight of approximately 272.25 g/mol. Arbutin exists in two forms: alpha-arbutin and beta-arbutin, with the alpha form being more stable and effective in skin-lightening applications. This compound is known for its ability to inhibit tyrosinase, an enzyme involved in melanin production, making it popular in cosmetic formulations aimed at reducing hyperpigmentation and promoting an even skin tone. Additionally, arbutin exhibits antioxidant properties, contributing to its potential health benefits. It is generally considered safe for topical use, although some individuals may experience sensitivity. In terms of solubility, arbutin is soluble in water and alcohol, which facilitates its incorporation into various formulations. Overall, arbutin is valued for its cosmetic applications and its role in traditional herbal medicine.

Formula: C₁₂H₁₆O₇

InChI: InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12-/m1/s1

InChI key: InChIKey=BJRNKVDFDLYUGJ-RMPHRYRLSA-N

SMILES: O([C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C2=CC=C(O)C=C2

Synonyms:

• 4-Hydroxyphenyl Hexopyranoside
• 4-Hydroxyphenyl β-<span class="text-smallcaps">D</span>-glucopyranoside
• 4-Hydroxyphenyl-Beta-D-Glucopyranoside
• 4-Hydroxyphenyl-β-D-glucopyranosid
• 4-hidroxifenil-β-D-glucopiranosido
• 4-hydroxyphenyl beta-D-galactopyranoside
• 4-hydroxyphenyl beta-D-glycero-hexopyranoside
• 4-hydroxyphenyl β-D-glucopyranoside
• 4-hydroxyphenyl-β-D-glucopyrannoside
• Arbutine
• Arbutoside
• Arbutosie
• Arbutyne
• Beta-Arbutin
• Glucopyranoside, p-hydroxyphenyl, β-<span class="text-smallcaps">D</span>-
• Glucopyranoside, p-hydroxyphenyl, β-D-
• Hydroquinone glucose
• Hydroquinone β-<span class="text-smallcaps">D</span>-glucopyranoside
• Hydroquinone β-D-glucopyranoside
• Hydroquinone-beta-D-glucopyranoside
• Nsc 4036
• P-Arbutin
• Ursin
• Uvasol
• p-Hydroxyphenyl β-<span class="text-smallcaps">D</span>-glucopyranoside
• p-Hydroxyphenyl β-<span class="text-smallcaps">D</span>-glucoside
• p-Hydroxyphenyl β-D-glucopyranoside
• p-Hydroxyphenyl β-D-glucoside
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, 4-hydroxyphenyl
• β-Arbutin
• β-D-Glucopyranoside, 4-hydroxyphenyl
• Arbutin
• .beta.-D-Glucopyranoside, 4-hydroxyphenyl
• 4-hydroxyphenyl-á-d-glucopyranoside
• ARBUTIN:B-D-GLUCOPYRANOSIDE, 4-HYDROXYPHENYL,
• HYDROQUINONE-BETA-D-GLUCOSIDE
• Arbutus extract
• Uresol
• ARBUTIN CRYSTALLINE SYNTHETIC
• ARBUTIN 98+%

Arbutin

CAS: 497-76-7

Formula: C₁₂H₁₆O₇

Purity: >95.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 272.25

Ref: 3B-A0522

Arbutin, 98+%

CAS: 497-76-7

Arbutin, a glycosylated hydroquinone, is used in studies on melanin biosynthesis and as an inhibitor to identify, differentiate and characterize tyrosinase(s). Also used in sed as a skin-lightening agent in cosmetic products. This Thermo Scientific Chemicals brand product was originally part of the

Formula: C₁₂H₁₆O₇

Purity: 98+%

Color and Shape: White to pale cream, Powder

Molecular weight: 272.25

Ref: 02-L14945

Arbutin

CAS: 497-76-7

Arbutin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₂H₁₆O₇

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 272.26

Ref: 11-0412S

ARBUTIN CRS

CAS: 497-76-7

ARBUTIN CRS

Formula: C₁₂H₁₆O₇

Color and Shape: White.

Molecular weight: 272.2512

Ref: 41-Y0000806

Arbutin

CAS: 497-76-7

Arbutin, a bearberry extract, blocks melanin by inhibiting tyrosinase.

Formula: C₁₂H₁₆O₇

Purity: 99.58% - 99.93%

Color and Shape: Colorless Elongated Prisms From Moist Ethyl Acetate White Powder

Molecular weight: 272.25

Ref: TM-T0473

4-​Hydroxyphenyl β-​D-​glucopyranoside

CAS: 497-76-7

Formula: C₁₂H₁₆O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 272.2512

Ref: IN-DA00I8VL

Arbutin

CAS: 497-76-7

Formula: C₁₂H₁₆O₇

Purity: ≥ 99.0%

Color and Shape: White or almost white crystalline powder

Molecular weight: 272.26

Ref: 7W-GC0919

Arbutin

CAS: 497-76-7

Arbutin

Purity: ≥98%

Molecular weight: 272.25g/mol

Ref: 54-BUP18160

Arbutin

CAS: 497-76-7

Formula: C₁₂H₁₆O₇

Color and Shape: White To Off-White Solid

Molecular weight: 272.25

Ref: 4Z-A-132002

Arbutin-d4

CAS: 497-76-7

Formula: C₁₂H₁₂D₄O₇

Color and Shape: Off-White Solid

Molecular weight: 276.28

Ref: 4Z-A-132003

Arbutin

CAS: 497-76-7

Formula: C₁₂H₁₆O₇

Purity: 95%~99%

Molecular weight: 272.253

Ref: BP-BP0185

Arbutin

CAS: 497-76-7

Arbutin

Purity: 98%

Molecular weight: 272.25g/mol

Ref: 54-BIK9002

Arbutin

CAS: 497-76-7

Natural glycoside

Formula: C₁₂H₁₆O₇

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 272.26

Ref: 5G-89510

Arbutin

CAS: 497-76-7

Applications Arbutin is a glycosylated hydroquinone extracted from bearberry plant. Arbutin is a known inhibitor of tyrosinase, which in turn prevents the formation of melanin. Arbutin is often used as a skin-lightening agent in cosmetic products.
References Magnusson, B., et al.: J. Invest. Dermatol., 52, 268 (1969), Goodwin, B., et al.: Contact Dermatitis, 7, 248, (1981), ,Itoh, M., et al.: J. Dermatol., 9, 223 (1982), Sugimoto, K., et al.: Biol. Pharm. Bull., 24, 510 (2004)

Formula: C₁₂H₁₆O₇

Color and Shape: Neat

Molecular weight: 272.25

Ref: TR-A766510

Arbutin - Natural origin

CAS: 497-76-7

Inhibitor of tyrosinase in melanocytes: skin whitener

Formula: C₁₂H₁₆O₇

Color and Shape: White Powder

Molecular weight: 272.25 g/mol

Ref: 3D-EA31688

Arbutin - Synthetic origin

CAS: 497-76-7

Inhibitor of tyrosinase in melanocytes: skin whitener

Formula: C₁₂H₁₆O₇

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 272.25 g/mol

Ref: 3D-EA01844

p-Arbutin extrapure, 98%

CAS: 497-76-7

Formula: C₁₂H₁₆O₇

Purity: min. 98%

Color and Shape: White, Crystalline powder, Clear, Colourless

Molecular weight: 272.26

Ref: SR-13492

Arbutin

CAS: 497-76-7

Formula: C₁₂H₁₆O₇

Purity: 95%

Color and Shape: Solid, Light brown powder

Molecular weight: 272.253

Ref: 10-F105900