CAS 497223-25-3

Cenicriviroc

Description:

Cenicriviroc is a small molecule that functions as an antagonist of the CCR5 and CCR2 chemokine receptors, which are involved in inflammatory processes and HIV infection. It is primarily investigated for its potential therapeutic applications in treating HIV and non-alcoholic steatohepatitis (NASH). The compound exhibits a unique mechanism of action by blocking the entry of HIV into host cells and modulating immune responses associated with liver inflammation. Cenicriviroc is characterized by its relatively low molecular weight and specific structural features that enable its receptor-binding capabilities. In preclinical and clinical studies, it has shown promise in reducing liver inflammation and fibrosis, making it a candidate for further research in liver-related diseases. Its pharmacokinetic profile indicates that it can be administered orally, and it has been evaluated for safety and efficacy in various clinical trials. As with any investigational drug, ongoing studies are essential to fully understand its therapeutic potential and long-term effects.

Formula: C₄₁H₅₂N₄O₄S

InChI: InChI=1S/C41H52N4O4S/c1-5-7-22-48-23-24-49-38-15-10-32(11-16-38)33-12-19-40-35(25-33)26-34(9-8-21-44(40)28-31(3)4)41(46)43-36-13-17-39(18-14-36)50(47)29-37-27-42-30-45(37)20-6-2/h10-19,25-27,30-31H,5-9,20-24,28-29H2,1-4H3,(H,43,46)/t50-/m0/s1

InChI key: InChIKey=PNDKCRDVVKJPKG-DPDRHGIRSA-N

SMILES: C(C(C)C)N1C=2C(=CC(=CC2)C3=CC=C(OCCOCCCC)C=C3)C=C(C(NC4=CC=C(S(CC=5N(CCC)C=NC5)=O)C=C4)=O)CCC1

Synonyms:

• (-)-8-[4-(2-Butoxyethoxy)phenyl]-1-isobutyl-N-[4-[[(1-propyl-1H-imidazol-5-yl)methyl]sulfinyl]phenyl]-1,2,3,4-tetrahydro-1-benzazocine-5-carboxamide
• TB 652
• 8-[4-(2-Butoxyethoxy)phenyl]-1,2,3,4-tetrahydro-1-(2-methylpropyl)-N-[4-[(S)-[(1-propyl-1H-imidazol-5-yl)methyl]sulfinyl]phenyl]-1-benzazocine-5-carboxamide
• Cenicriviroc
• 1-Benzazocine-5-carboxamide, 8-[4-(2-butoxyethoxy)phenyl]-1,2,3,4-tetrahydro-1-(2-methylpropyl)-N-[4-[(S)-[(1-propyl-1H-imidazol-5-yl)methyl]sulfinyl]phenyl]-

Cenicriviroc

CAS: 497223-25-3

Formula: C₄₁H₅₂N₄O₄S

Purity: 95%

Color and Shape: Solid

Molecular weight: 696.9410

Ref: IN-DA00DFA1

(S)-8-(4-(2-Butoxyethoxy)Phenyl)-1-Isobutyl-N-(4-(((1-Propyl-1H-Imidazol-5-Yl)Methyl)Sulfinyl)Phenyl)-1,2,3,4-Tetrahydrobenzo[B]Azocine-5-Carboxamide

CAS: 497223-25-3

(S)-8-(4-(2-Butoxyethoxy)Phenyl)-1-Isobutyl-N-(4-(((1-Propyl-1H-Imidazol-5-Yl)Methyl)Sulfinyl)Phenyl)-1,2,3,4-Tetrahydrobenzo[B]Azocine-5-Carboxamide

Purity: 95%

Molecular weight: 696.94g/mol

Ref: 54-OR1023808

Cenicriviroc

CAS: 497223-25-3

Cenicriviroc

Purity: ≥95%

Molecular weight: 696.94g/mol

Ref: 54-BUP08866

Cenicriviroc

CAS: 497223-25-3

Formula: C₄₁H₅₂N₄O₄S

Color and Shape: Pale Yellow Solid

Molecular weight: 696.96

Ref: 4Z-C-159001

Cenicriviroc

CAS: 497223-25-3

Cenicriviroc (TAK-652), oral CCR2/CCR5 blocker, inhibits HIV-1/HIV-2, with strong anti-infective/anti-inflammatory effects.

Formula: C₄₁H₅₂N₄O₄S

Purity: 97.87%

Color and Shape: Solid

Molecular weight: 696.94

Ref: TM-TQ0297

CENICRIVIROC

CAS: 497223-25-3

Purity: 97%

Molecular weight: 696.9500122

Ref: 10-F799803

Cenicriviroc-d9

Controlled Product

CAS: 497223-25-3

Formula: C₄₁D₉H₄₃N₄O₄S

Color and Shape: Neat

Molecular weight: 705.996

Ref: TR-C256552

Cenicriviroc

Controlled Product

CAS: 497223-25-3

Formula: C₄₁H₅₂N₄O₄S

Color and Shape: Neat

Molecular weight: 696.941

Ref: TR-C256550