CAS 49745-95-1

Dobutamine hydrochloride

Description:

Dobutamine hydrochloride is a synthetic catecholamine and a potent inotropic agent primarily used in the treatment of heart failure and cardiogenic shock. It acts primarily on beta-1 adrenergic receptors, leading to increased myocardial contractility and improved cardiac output without significantly increasing heart rate. The substance is typically administered intravenously due to its rapid onset of action and short half-life. Dobutamine hydrochloride is a white to off-white crystalline powder that is soluble in water and has a pH range that is generally neutral. Its chemical formula is C18H23N3O3·HCl, and it has a molecular weight of approximately 345.86 g/mol. The compound is often used in clinical settings for stress echocardiography and to manage patients with acute heart failure. As with any medication, it is essential to monitor patients for potential side effects, including arrhythmias and hypotension, during its administration.

Formula: C₁₈H₂₃NO₃·ClH

InChI: InChI=1S/C18H23NO3.ClH/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15;/h4-9,12-13,19-22H,2-3,10-11H2,1H3;1H

InChI key: InChIKey=BQKADKWNRWCIJL-UHFFFAOYSA-N

SMILES: C(CNC(CCC1=CC=C(O)C=C1)C)C2=CC(O)=C(O)C=C2.Cl

Synonyms:

• 1,2-Benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, hydrochloride
• 1,2-Benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, hydrochloride (1:1)
• 4-(2-{[4-(4-Hydroxyphenyl)Butan-2-Yl]Amino}Ethyl)Benzene-1,2-Diol Hydrochloride (1:1)
• <span class="text-smallcaps">DL</span>-Dobutamine hydrochloride
• Benzene-1,2-Diol Hydrochloride
• Dobutamine Hydrochloride
• Dobutrex
• Inotrex
• NSC 299583
• dl-Dobutamine hydrochloride

Dobutamine Hydrochloride

CAS: 34368-04-2, 49745-95-1

Formula: C₁₈H₂₃NO₃·HCl

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 337.84

Ref: 3B-D4335

Dobutamine hydrochloride

CAS: 49745-95-1

Dobutamine hydrochloride is a catecholamine that acts as a -adrenergic receptor agonist. It has its strongest effects on 1 receptors, with lesser but significant 2 receptor activation and only weak 1 receptor actions. As a result, it strongly increases cardiac contractility with modest chronotropic,

Formula: C₁₈H₂₄ClNO₃

Color and Shape: Powder, White to off-white

Molecular weight: 337.84

Ref: 02-J61333

Dobutamine hydrochloride

CAS: 49745-95-1

Dobutamine hydrochloride

Formula: C₁₈H₂₃NO₃ / C₁₈H₂₃NO₃HCl

Purity: 89.1% / 99.9%

Color and Shape: Off-White

Molecular weight: 301.16779

Ref: 47-674

DOBUTAMINE HYDROCHLORIDE CRS

CAS: 49745-95-1

DOBUTAMINE HYDROCHLORIDE CRS

Ref: 41-D2954000

Dobutamine Hydrochloride

CAS: 49745-95-1

Amino-naphthols and other amino-phenols, their ethers and esters, other than those cont more than one kind of oxygen function; salts thereof nesoi

Formula: C₁₈H₂₃NO₃·HCl

Color and Shape: White Off-White Crystalline Powder

Molecular weight: 337.14447

Ref: 45-1224507

Dobutamine Hydrochloride

CAS: 49745-95-1

Dobutamine Hydrochloride

Purity: 98%

Molecular weight: 337.84g/mol

Ref: 54-OR1024667

Dobutamine hydrochloride

CAS: 49745-95-1

Dobutamine hydrochloride

Purity: ≥95%

Molecular weight: 337.84g/mol

Ref: 54-BUP11279

Dobutamine hydrochloride

CAS: 49745-95-1

Formula: C₁₈H₂₃NO₃HCl

Molecular weight: 337.85

Ref: 7W-GP1178

Dobutamine Hydrochloride

Controlled Product

CAS: 49745-95-1

Formula: C₁₈H₂₃NO₃·ClH

Color and Shape: Neat

Molecular weight: 337.84

Ref: 86-MM0675.00

Dobutamine hydrochloride

CAS: 49745-95-1

Formula: C₁₈H₂₄ClNO₃

Purity: 95%~99%

Molecular weight: 337.844

Ref: BP-BP4215

Dobutamine hydrochloride

CAS: 49745-95-1

Dobutamine hydrochloride (Dobutamine (hydrochloride)) is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects.

Formula: C₁₈H₂₄ClNO₃

Purity: 97.15% - 99.94%

Color and Shape: Solid

Molecular weight: 337.84

Ref: TM-T8149

Dobutamine Hydrochloride RS

CAS: 49745-95-1

Color and Shape: White To Very Pale Orange

Ref: 2K-1091000021

rac Dobutamine Hydrochloride

CAS: 49745-95-1

Stability Hygroscopic
Applications A sympathomimetic drug used to treat heart failure by inhibiting β1 receptors in the sympathetic nervous system. Cardiotonic.
References Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 2881 (2005), Abdel F., et al.: J. Drug Res., 29, 83 (2008), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),

Formula: C₁₈H₂₃NO₃·ClH

Color and Shape: Off-White

Molecular weight: 337.84

Ref: TR-D494445

Dobutamine Hydrochloride

CAS: 49745-95-1

Formula: C₁₈H₂₃NO₃HCl

Molecular weight: 301.38 : 36.46

Ref: ST-EA-CP-D59000

4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]amino]ethyl]-1,2-benzenediol hydrochloride

CAS: 49745-95-1

Dobutamine is a beta-adrenergic agonist that causes the heart to contract and increase blood pressure. It is used for pharmacological treatment of congestive heart failure and ventricular arrhythmias, as well as during angiography of the coronary arteries. Dobutamine stimulates dopamine receptors in the heart, which increases the systolic pressure. Dobutamine has been shown to be effective in improving myocardial contractility, left ventricle function, and cardiac output in patients with chronic congestive heart failure. This drug also improves left ventricular regional wall motion, papillary muscle function, and mitral valve regurgitation. Dobutamine may cause side effects such as nausea, vomiting, headache, or chest pain.

Formula: C₁₈H₂₄ClNO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 337.84 g/mol

Ref: 3D-FH27507

Dobutamine hydrochloride

CAS: 49745-95-1

Formula: C₁₈H₂₄ClNO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 337.84

Ref: 10-F240166