CAS 49746-04-5

Thiothixene hydrochloride

Description:

Thiothixene hydrochloride is an antipsychotic medication primarily used in the treatment of schizophrenia and other psychotic disorders. It belongs to the thioxanthene class of drugs and functions as a dopamine antagonist, which helps to balance neurotransmitters in the brain. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for oral administration. Its mechanism of action involves blocking dopamine receptors, particularly D2 receptors, which can help alleviate symptoms such as hallucinations and delusions. Thiothixene hydrochloride may also exhibit some affinity for serotonin receptors, contributing to its therapeutic effects. Common side effects can include sedation, weight gain, and extrapyramidal symptoms, which are movement disorders resulting from dopamine blockade. As with any antipsychotic, careful monitoring is essential to manage potential adverse effects and ensure effective treatment. It is important to note that this medication should only be used under the guidance of a healthcare professional.

Formula: C₂₃H₂₉N₃O₂S₂·2ClH

InChI: InChI=1S/C23H29N3O2S2.2ClH/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26;;/h4-5,7-11,17H,6,12-16H2,1-3H3;2*1H/b19-8-;;

InChI key: InChIKey=SSRKPUYBAUMQED-INHJUQNSSA-N

SMILES: C(\CCN1CCN(C)CC1)=C/2\C=3C(SC=4C2=CC=CC4)=CC=C(S(N(C)C)(=O)=O)C3.Cl

Synonyms:

• 9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-, hydrochloride (1:2), (9Z)-
• Thiothixene hydrochloride
• 9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-, dihydrochloride, (9Z)-

Thiothixene hydrochloride

CAS: 49746-04-5

Thiothixene hydrochloride is an antipsychotic agent that can be used in the study of schizophrenia and bipolar mania.

Formula: C₂₃H₃₀ClN₃O₂S₂

Color and Shape: Solid

Molecular weight: 480.08

Ref: TM-T63592