CAS 497839-62-0: 6-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Description: The chemical substance known as 6-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, with the CAS number 497839-62-0, is a synthetic organic compound characterized by its complex structure, which includes a pyrrolo[2,3-d]pyrimidine core. This compound features multiple functional groups, including an amine and a piperazine moiety, which contribute to its potential biological activity. The presence of the ethyl group and the phenylethyl substituent suggests that it may interact with various biological targets, possibly influencing receptor binding or enzyme activity. Its molecular structure indicates potential for use in medicinal chemistry, particularly in the development of pharmaceuticals aimed at treating conditions related to the central nervous system or other therapeutic areas. The compound's solubility, stability, and reactivity would depend on its specific functional groups and overall molecular conformation, making it a candidate for further investigation in drug development and pharmacological studies.

Formula: C₂₇H₃₂N₆

InChI: InChI=1S/C27H32N6/c1-3-32-13-15-33(16-14-32)18-21-9-11-23(12-10-21)25-17-24-26(28-19-29-27(24)31-25)30-20(2)22-7-5-4-6-8-22/h4-12,17,19-20H,3,13-16,18H2,1-2H3,(H2,28,29,30,31)/t20-/m1/s1

InChI key: InChIKey=OONFNUWBHFSNBT-HXUWFJFHSA-N

SMILES: N=1C=NC(NC(C=2C=CC=CC2)C)=C3C=C(NC13)C4=CC=C(C=C4)CN5CCN(CC)CC5

Synonyms:

• 1H-Pyrrolo[2,3-d]pyrimidin-4-amine,6-[4-[(4-ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-
• 6-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• 6-{4-[(4-Ethyl-1-piperazinyl)methyl]phenyl}-N-[(1R)-1-phenylethyl]-1H-pyrrolo[2,3-d]pyrimidin-4-amine
• Aee-788
• Aee788
• Nvp-Aee 788
• [6-[4-[(4-Ethylpiperazin-1-yl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-((R)-1-phenylethyl)amine
• 7H-pyrrolo[2,3-d]pyrimidin-4-amine, 6-[4-[(4-ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-
• 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 6-[4-[(4-ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-

AEE788

CAS: 497839-62-0

• Molecular weight: 440.58g/mol

AEE788

CAS: 497839-62-0

• Purity: 98.93%
• Molecular weight: 440.58g/mol

AEE 788

CAS: 497839-62-0

• Formula: C₂₇H₃₂N₆
• Purity: >98.0%(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 440.60

AEE788

CAS: 497839-62-0

AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, …

• Formula: C₂₇H₃₂N₆
• Purity: 100% - 98.94%
• Color and Shape: Solid
• Molecular weight: 440.58

AEE 788

CAS: 497839-62-0

Dual inhibitor of EGFR and VEGR receptor phosphorylation; anti-metastatic

• Formula: C₂₇H₃₂N₆
• Purity: Min. 95%
• Molecular weight: 440.58 g/mol