CAS 497839-62-0

6-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Description:

The chemical substance known as 6-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, with the CAS number 497839-62-0, is a synthetic organic compound characterized by its complex structure, which includes a pyrrolo[2,3-d]pyrimidine core. This compound features multiple functional groups, including an amine and a piperazine moiety, which contribute to its potential biological activity. The presence of the ethyl group and the phenylethyl substituent suggests that it may interact with various biological targets, possibly influencing receptor binding or enzyme activity. Its molecular structure indicates potential for use in medicinal chemistry, particularly in the development of pharmaceuticals aimed at treating conditions related to the central nervous system or other therapeutic areas. The compound's solubility, stability, and reactivity would depend on its specific functional groups and overall molecular conformation, making it a candidate for further investigation in drug development and pharmacological studies.

Formula: C₂₇H₃₂N₆

InChI: InChI=1S/C27H32N6/c1-3-32-13-15-33(16-14-32)18-21-9-11-23(12-10-21)25-17-24-26(28-19-29-27(24)31-25)30-20(2)22-7-5-4-6-8-22/h4-12,17,19-20H,3,13-16,18H2,1-2H3,(H2,28,29,30,31)/t20-/m1/s1

InChI key: InChIKey=OONFNUWBHFSNBT-HXUWFJFHSA-N

SMILES: N([C@H](C)C1=CC=CC=C1)C2=C3C(NC(=C3)C4=CC=C(CN5CCN(CC)CC5)C=C4)=NC=N2

Synonyms:

• 1H-Pyrrolo[2,3-d]pyrimidin-4-amine,6-[4-[(4-ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-
• 6-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• 6-{4-[(4-Ethyl-1-piperazinyl)methyl]phenyl}-N-[(1R)-1-phenylethyl]-1H-pyrrolo[2,3-d]pyrimidin-4-amine
• Aee-788
• Aee788
• Nvp-Aee 788
• [6-[4-[(4-Ethylpiperazin-1-yl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-((R)-1-phenylethyl)amine
• 7H-pyrrolo[2,3-d]pyrimidin-4-amine, 6-[4-[(4-ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-
• 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 6-[4-[(4-ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-

AEE788

CAS: 497839-62-0

AEE788

Purity: 97%

Molecular weight: 440.58g/mol

Ref: 54-OR1023737

AEE788

CAS: 497839-62-0

AEE788

Purity: ≥98%

Molecular weight: 440.58g/mol

Ref: 54-BUP09729

AEE 788

CAS: 497839-62-0

Formula: C₂₇H₃₂N₆

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 440.60

Ref: 3B-A3271

AEE788

CAS: 497839-62-0

AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.

Formula: C₂₇H₃₂N₆

Purity: 98% - >99.99%

Color and Shape: Solid

Molecular weight: 440.58

Ref: TM-T2116

AEE 788

CAS: 497839-62-0

Dual inhibitor of EGFR and VEGR receptor phosphorylation; anti-metastatic

Formula: C₂₇H₃₂N₆

Purity: Min. 95%

Molecular weight: 440.58 g/mol

Ref: 3D-FA17229