5-Isoxazoleacetic acid is an organic compound characterized by its isoxazole ring structure, which is a five-membered heterocyclic compound containing both nitrogen and oxygen atoms. This substance typically exhibits properties such as being a white to off-white crystalline solid, and it is soluble in polar solvents like water and alcohols. The presence of the carboxylic acid functional group contributes to its acidic nature, allowing it to participate in various chemical reactions, including esterification and amidation. 5-Isoxazoleacetic acid is of interest in medicinal chemistry and pharmacology, as it may exhibit biological activity, potentially serving as a precursor or intermediate in the synthesis of pharmaceuticals. Its molecular structure allows for interactions with biological targets, making it a subject of research in drug development. Additionally, its stability under standard laboratory conditions makes it suitable for various synthetic applications. As with many chemical substances, proper handling and safety precautions are essential due to its potential reactivity and biological effects.

5-Isoxazoleacetic acid

4992-21-6: 5-Isoxazoleacetic acid is an organic compound characterized by its isoxazole ring structure, which is a five-membered heterocyclic compound containing both nitrogen and oxygen atoms. This substance typically exhibits properties such as being a white to off-white crystalline solid, and it is soluble in polar solvents like water and alcohols. The presence of the carboxylic acid functional group contributes to its acidic nature, allowing it to participate in various chemical reactions, including esterification and amidation. 5-Isoxazoleacetic acid is of interest in medicinal chemistry and pharmacology, as it may exhibit biological activity, potentially serving as a precursor or intermediate in the synthesis of pharmaceuticals. Its molecular structure allows for interactions with biological targets, making it a subject of research in drug development. Additionally, its stability under standard laboratory conditions makes it suitable for various synthetic applications. As with many chemical substances, proper handling and safety precautions are essential due to its potential reactivity and biological effects.

2-(1,2-Oxazol-5-yl)acetic acid is a cell-permeable compound that induces death of cancer cells via apoptosis. It has been shown to be effective in vitro against mouse melanoma cells, as well as in vivo treatment of mice with xenografts of human melanoma cells. This drug activates caspase 3 by inhibiting the mitochondrial membrane potential and releasing cytochrome C from mitochondria into the cytosol. 2-(1,2-Oxazol-5-yl)acetic acid also mediates apoptotic cell death by activating the chloride channel, reactive oxygen species (ROS), and voltage gated ion channels. In addition, it inhibits viral replication by inducing autophagic cell death and has tumoricidal effects when given to mice with established tumors.
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CAS 4992-21-6

5-Isoxazoleacetic acid

5-Isoxazoleacetic acid

Ref: IN-DA01DEW4

2-(1,2-Oxazol-5-yl)acetic acid

Ref: 3D-EAA99221