CAS 50-01-1

Guanidine hydrochloride

Description:

Guanidine hydrochloride is a white crystalline solid with the chemical formula CH5ClN4. It is a strong chaotropic agent, meaning it disrupts the structure of water and can denature proteins, making it useful in biochemical applications, particularly in protein purification and refolding. This compound is highly soluble in water and has a high pH, making it alkaline in nature. It is often used in molecular biology and biochemistry for its ability to solubilize proteins and nucleic acids. Guanidine hydrochloride is also known for its role in the extraction of RNA and DNA, as well as in various laboratory protocols involving protein studies. However, it is important to handle this substance with care, as it can be toxic and irritating to the skin, eyes, and respiratory system. Proper safety measures, including the use of personal protective equipment, are recommended when working with guanidine hydrochloride in laboratory settings.

Formula: CH₅N₃·ClH

InChI: InChI=1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H

InChI key: InChIKey=PJJJBBJSCAKJQF-UHFFFAOYSA-N

SMILES: C(=N)(N)N.Cl

Synonyms:

• Buffer AL
• Chlorure de guanidinium
• Cloruro De Guanidinio
• Guanidin.Hcl
• Guanidine Hydrochloride
• Guanidine chloride
• Guanidine, hydrochloride (1:1)
• Guanidinium Chloride
• Guanidinium hydrochloride
• Guanidiniumchlorid
• Guanidine, monohydrochloride
• methanaminium, 1-amino-1-imino-, hydrochloride (1:1)
• Guanidine Hydrochlorie
• Guanidine HCl

Guanidine hydrochloride solution, 8M

CAS: 50-01-1

Formula: CH₅N₃·HCl

Color and Shape: Clear, colourless liquid

Molecular weight: 95.53

Ref: 7W-GE1001

Guanidine HCl

CAS: 50-01-1

Guanidine is a guanidine salt that is used in the chemical industry as a raw material for the manufacture of plastics and synthetic rubber. It is also used as a disinfectant and deodorizer in wastewater treatment. The reaction mechanism of guanidine HCl involves hydrogen bonding interactions with the metal hydroxides and receptor activity. Guanidine has been shown to have an inhibitory effect on mucin gene expression, which may be due to its ability to inhibit toll-like receptor signalling pathways.

Formula: CH₅N₃·HCl

Color and Shape: White Powder

Molecular weight: 95.5 g/mol

Ref: 3D-FG09296

Guanidine Hydrochloride (GHC) extrapure for biochemistry, 99%

CAS: 50-01-1

Formula: CH₅N₃·HCl

Purity: min. 99%

Color and Shape: White, Crystalline compound, Clear, Colourless

Molecular weight: 95.53

Ref: SR-25722

Guanidine Hydrochloride (GHC) pure, 99%

CAS: 50-01-1

Formula: CH₅N₃HCl

Purity: min. 99%

Color and Shape: White, Crystalline powder

Molecular weight: 95.53

Ref: SR-54542

Guanidine Hydrochloride (GHC) for molecular biology, 99.5%

CAS: 50-01-1

Formula: CH₅N₃·HCl

Purity: min. 99.5%

Color and Shape: White, Crystalline compound, Clear, Colourless

Molecular weight: 95.53

Ref: SR-45539

Guanidine Hydrochloride (GHC) ExiPlus, Multi-Compendial, 99%

CAS: 50-01-1

Formula: CH₅N₃·HCl

Purity: min. 99.5%

Color and Shape: White, Crystalline compound, Clear, Colourless

Molecular weight: 95.53

Ref: SR-68413

Guanidine Hydrochloride

Controlled Product

CAS: 50-01-1

Stability Hygroscpic
Applications Guanidine has a good bacterial and fungicidal efficacy when used in low concentration and can also be used as disinfectant.
References Laemmli, U., et al.: Nature, 227, 680 (1970), Nissen, N., et al.: Biochem. J., 338, 637 (1999), Gibson, C., et al.: Circulation, 101, 125 (2000),

Formula: CH₅N₃·ClH

Color and Shape: White

Molecular weight: 95.53

Ref: TR-G821245

Guanidine hydrochloride

CAS: 50-01-1

Guanidine hydrochloride is an important reagent in organic synthesis. It is a solid chemical that is soluble in water and other polar solvents. It is also used as a building block for the preparation of fine chemicals and pharmaceuticals. CAS No. 50-01-1

Formula: CH₆ClN₃

Molecular weight: 95.53 g/mol

Ref: 3D-G-8000

Guanidine HCl - 60% solution in H2O

CAS: 50-01-1

Guanidine HCl is a strong base that reacts with acids to form their salts. It is used in disinfectant solutions, where it binds to proteins and other organic matter, forming soluble complexes that can be easily removed. Guanidine HCl has been shown to have toxicological effects on the respiratory system of rats and mice. This is due to its ability to cause mucin gene expression in human lung cells, which leads to physiological effects such as mucous production. The reaction mechanism for guanidine HCl involves hydrogen bonding interactions with metal hydroxides.

Formula: CH₆ClN₃

Purity: Min. 95%

Molecular weight: 95.53 g/mol

Ref: 3D-FG177263