CAS 50-07-7: Mitomycin C

Description: Mitomycin C is a potent antitumor antibiotic derived from the bacterium Streptomyces caespitosus. It is classified as an alkylating agent, which means it interferes with DNA synthesis and function, making it effective in treating various cancers, particularly in cases of bladder and gastrointestinal tumors. The compound exhibits a unique mechanism of action by forming cross-links between DNA strands, ultimately leading to cell death. Mitomycin C is typically administered intravenously and is known for its cytotoxic effects, which can result in significant side effects, including myelosuppression, nausea, and potential organ toxicity. Its chemical structure features a quinone moiety, which plays a crucial role in its reactivity and biological activity. Due to its effectiveness, Mitomycin C is often used in combination with other chemotherapeutic agents to enhance therapeutic outcomes. However, careful monitoring is essential during treatment to manage adverse effects and ensure patient safety.

Formula: C₁₅H₁₈N₄O₅

InChI: InChI=1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1

InChI key: InChIKey=NWIBSHFKIJFRCO-WUDYKRTCSA-N

SMILES: O=C(OCC1C=2C(=O)C(N)=C(C(=O)C2N3CC4NC4C31OC)C)N

Synonyms:

• (1aS,8S,8aR,8bS)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2′,3′:3,4]pyrrolo[1,2-a]indole-4,7-dione
• (6-Amino-8A-Methoxy-5-Methyl-4,7-Dioxo-1,1A,2,4,7,8,8A,8B-Octahydroazireno[2',3':3,4]Pyrrolo[1,2-A]Indol-8-Yl)Methyl Carbamate
• 6-Amino-1,1A,2,8,8A,8B-Hexahydro-8-(Hydroxymethyl)-8A-Methoxy-5-Methylazirino[2',3':3,4]Pyrrolo[1,2-A]Indole-4,7-Dione Carbamate (Ester)
• Ametycine
• Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methoxy-5-methyl-, carbamate (ester)
• Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, (1aS,8S,8aR,8bS)-
• Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, [1aS-(1aα,8β,8aα,8bα)]-
• Azirino[2′,3′:3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methoxy-5-methyl-, carbamate (ester)
• Azirino[2′,3′:3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, (1aS,8S,8aR,8bS)-
• Azirino[2′,3′:3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, [1aS-(1aα,8β,8aα,8bα)]-
• MMC
• MitoExtra
• Mitocin C
• Mitomicina
• Mitomycin C
• Mitomycin C, Streptomyces caespitosus
• Mitomycine
• Mitonco
• Mitoplus
• Mitozytrex
• Mutamycin
• Mytomycin C
• Mytomycin Kyowa S
• Nsc 26980
• [(1aR,8R,8aS,8bR)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate
• [(1aS,8S,8aR,8bS)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate
• [(8R,8aS,8bR)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate
• [1Ar-(1Aalpha,8Beta,8Aalpha,8Balpha)]-6-Amino-8-[[(Aminocarbonyl)Oxy]Methyl]-1,1A,2,8,8A,8B-Hexahydro-8A-Methoxy-5-Methylazirino[2',3':3,4]Pyrrolo[1,2-Alpha]Indole-4,7-Dione
• mitomycin C from streptomyces*caespitosus
• tomycin C

Ametycin

CAS: 50-07-7

• Formula: C₁₅H₁₈N₄O₅
• Purity: >98.0%(HPLC)
• Color and Shape: Dark red to Dark purple to Dark blue powder to crystal
• Molecular weight: 334.33

Mitomycin C, 5 mg/ml in DMSO, sterile-filtered

CAS: 50-07-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. …

• Formula: C₁₅H₁₈N₄O₅
• Color and Shape: Liquid
• Molecular weight: 334.33

Mitomycin CRS

CAS: 50-07-7

• Color and Shape: Powder

Mitomycin

CAS: 50-07-7

Antibiotics nesoi

• Formula: C₁₅H₁₈N₄O₅
• Color and Shape: Blue Violet Powder
• Molecular weight: 334.12772

Mitomycin C

CAS: 50-07-7

• Formula: C₁₅H₁₈N₄O₅
• Purity: (HPLC) ≥ 98.0%
• Color and Shape: Grey, violet or blue powder
• Molecular weight: 334.33

Mitomycin C

CAS: 50-07-7

• Formula: C₁₅H₁₈N₄O₅
• Purity: By hplc: 99.1% (Typical Value in Batch COA)
• Color and Shape: blue-violet solid
• Molecular weight: 334.33g/mol

Mitomycin C

CAS: 50-07-7

• Formula: C₁₅H₁₈N₄O₅
• Color and Shape: Blue-Violet Solid
• Molecular weight: 334.33

Mitomycin C, 4% (with sodium chloride)

CAS: 50-07-7

• Formula: C₁₅H₁₈N₄O₅
• Color and Shape: Grey to blue-purple powder
• Molecular weight: 334.33

Mitomycin

CAS: 50-07-7

• Formula: C₁₅H₁₈N₄O₅
• Color and Shape: Neat
• Molecular weight: 334.33

Mitomycin 100 µg/mL in Acetonitrile

CAS: 50-07-7

• Formula: C₁₅H₁₈N₄O₅
• Color and Shape: Single Solution
• Molecular weight: 334.33

Mitomycin C, contains 2 mg Mitomycin C and 48 mg NaCl

CAS: 50-07-77647-14-5

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₅H₁₈N₄O₅
• Color and Shape: Grey to blue, Powder
• Molecular weight: 334.33

Mitomycin

CAS: 50-07-7

• Formula: C₁₅H₁₈N₄O₅
• Color and Shape: Neat
• Molecular weight: 334.33

Mitomycin C

CAS: 50-07-7

Stability Hygroscopic Applications Mitomycin C is an antitumor antibiotic. It is antineoplastic. Not a dangerous …

• Formula: C₁₅H₁₈N₄O₅
• Color and Shape: Violet
• Molecular weight: 334.33

Mitomycin C - Bio-X ™

CAS: 50-07-7

Mitomycin C is a cytotoxic agent that belongs to the class of mitomycins. It has …

• Formula: C₁₅H₁₈N₄O₅
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 334.33 g/mol

Mitomycin C - High Purity

CAS: 50-07-7

Mitomycin C is a cytotoxic agent that inhibits DNA synthesis. This product is tested according …

• Formula: C₁₅H₁₈N₄O₅
• Purity: Cas Rn [50-07-7] M. F. C15H18N4O5
• Color and Shape: Powder
• Molecular weight: 334.33 g/mol

Mitomycin C

CAS: 50-07-7

Chemoterapeutic agent; DNA crosslinker

• Formula: C₁₅H₁₈N₄O₅
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 334.33 g/mol