CAS 50-12-4

(±)-Mephenytoin

Description:

(±)-Mephenytoin, also known as Mephenytoin, is an anticonvulsant medication primarily used in the treatment of epilepsy. It belongs to the class of hydantoins and is characterized by its ability to stabilize neuronal membranes and reduce seizure activity. The compound exhibits a chiral nature, meaning it exists in two enantiomeric forms, which can have different pharmacological effects. Mephenytoin is typically administered orally and is metabolized in the liver, with its pharmacokinetics influenced by genetic factors and interactions with other medications. The substance is known for its potential side effects, which may include dizziness, drowsiness, and gastrointestinal disturbances. Additionally, it has a narrow therapeutic index, necessitating careful monitoring of blood levels to avoid toxicity. As with many anticonvulsants, it may also have implications for pregnancy and lactation, requiring a thorough risk-benefit analysis before use. Overall, (±)-Mephenytoin plays a significant role in managing certain types of seizures, although its use has declined with the advent of newer antiepileptic drugs.

Formula: C₁₂H₁₄N₂O₂

InChI: InChI=1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)

InChI key: InChIKey=GMHKMTDVRCWUDX-UHFFFAOYSA-N

SMILES: C(C)C1(C(=O)N(C)C(=O)N1)C2=CC=CC=C2

Synonyms:

• (.+-.)-5-Ethyl-3-methyl-5-phenylhydantoin
• (.+-.)-Mephenytoin
• (.+-.)-Mesantoin
• 3-Ethylnirvanol
• 3-Methyl-5-ethyl-5-phenyl-2,4-imidazolidinedione
• 3-Methyl-5-ethyl-5-phenylhydantoin
• 5-Ethyl-3-methyl-5-phenyl-2,4(3H,5H)-imidazoledione
• 5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione
• 5-Ethyl-3-methyl-5-phenylimidazolidin-2,4-dione
• <span class="text-smallcaps">DL</span>-Mephenytoin
• DL-Mephenytoin
• Epiazin
• Epilan
• Fenantoin
• Gerot-Epilan
• Hydantoin, 5-ethyl-3-methyl-5-phenyl-
• Insulton
• Mefenitoina
• Mephenytoine
• Mesdontoin
• Mesontoin
• Methoin
• Methylphenetoin
• Metydan
• Nsc 34652
• Phenantoin
• Phenylethylmethylhydantoin
• Sacerno
• Sedantional
• Sedantoin
• Triantoin

Mephenytoin

CAS: 50-12-4

Formula: C₁₂H₁₄N₂O₂

Purity: 98.0 - 102.0 % (dry basis)

Color and Shape: White to off-white crystalline powder

Molecular weight: 218.25

Ref: 7W-GL1129

5-Ethyl-3-Methyl-5-Phenylimidazolidine-2,4-Dione

CAS: 50-12-4

5-Ethyl-3-Methyl-5-Phenylimidazolidine-2,4-Dione

Purity: 98%

Molecular weight: 218.25g/mol

Ref: 54-OR1022940

Mephenytoin

CAS: 50-12-4

Mephenytoin

Purity: ≥98%

Molecular weight: 218.25g/mol

Ref: 54-BUP11972

Mephenytoin

CAS: 50-12-4

Mephenytoin (Phenantoin) is an anticonvulsant and a substrate of CYP2C19 and CYP2B6.

Formula: C₁₂H₁₄N₂O₂

Purity: 99.67% - 99.91%

Color and Shape: Crystals Solid

Molecular weight: 218.25

Ref: TM-T21425

rac-Mephenytoin

Controlled Product

CAS: 50-12-4

Applications rac-Mephenytoin is an anticonvulsant agent.
References Shimada, et al.: Anal. Biochem., 147, 174 (1975), Dzhagatspanyan. IA., et al.: Pharm. Chem. J., 25, 181 (1991),

Formula: C₁₂H₁₄N₂O₂

Color and Shape: White Solid

Molecular weight: 218.25

Ref: TR-M224985

Mephenytoin

CAS: 50-12-4

Mephenytoin is a drug that inhibits the activity of CYP2C19, which is an enzyme in the cytochrome P450 system. It has been shown to be effective in treating chronic viral hepatitis and autoimmune diseases such as psoriasis. The minimal toxicity of mephenytoin makes it a desirable candidate for use in chronic oral therapy. This drug also interacts with many other drugs, including nonsteroidal anti-inflammatory drugs, which may cause an increase or decrease in their effectiveness. Mephenytoin has been shown to inhibit the activities of the polymerase chain reaction (PCR) and reverse transcriptase in humans, making it useful for analytical purposes.

Formula: C₁₂H₁₄N₂O₂

Purity: Min. 95%

Molecular weight: 218.25 g/mol

Ref: 3D-AAA05012

Mephenytoin

CAS: 50-12-4

Color and Shape: Neat

Ref: 61-FOR0348.00

Mephenytoin 1.0 mg/ml in Methanol

CAS: 50-12-4

Color and Shape: Single Solution

Ref: 61-AMP0348.00-01