CAS 50-22-6

corticosterone

Description:

Corticosterone is a steroid hormone belonging to the class of glucocorticoids, primarily produced in the adrenal cortex of vertebrates. It plays a crucial role in the regulation of various physiological processes, including metabolism, immune response, and stress response. Corticosterone is involved in the regulation of glucose levels, influencing carbohydrate metabolism, and has anti-inflammatory effects. Its chemical structure features a steroid backbone, characterized by four fused carbon rings, with specific functional groups that contribute to its biological activity. The CAS number 50-22-6 uniquely identifies corticosterone in chemical databases. In terms of solubility, corticosterone is relatively lipophilic, allowing it to easily cross cell membranes and exert its effects on target tissues. It is also important in research and clinical settings, particularly in studies related to stress, adrenal function, and various endocrine disorders. Corticosterone levels can be measured in biological samples, providing insights into an organism's physiological state and response to stressors.

Formula: C₂₁H₃₀O₄

InChI: InChI=1/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1

InChI key: InChIKey=OMFXVFTZEKFJBZ-HJTSIMOOSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(C[C@@H]3O)[C@@H](C(CO)=O)CC4)[H])(CCC1=CC(=O)CC2)[H])[H]

Synonyms:

• (11Beta)-11,21-Dihydroxypregn-4-Ene-3,20-Dione
• (11β)-11,21-Dihydroxypregn-4-ene-3,20-dione
• 11,21-Dihydroxyprogesterone
• 11-Beta,21-Dihydroxypregn-4-Ene-3,20-Dione
• 11-Hydroxycorticoaldosterone
• 11β,21-Dihydroxypregn-4-ene-3,20-dione
• 11β,21-Dihydroxyprogesterone
• 17-Deoxycortisol
• 4-Pregnen-11?21-diol-3,20-dione
• 4-Pregnene-11β,21-diol-3,20-dione
• Corticosteron
• Corticosterona
• Kendall's compound B
• Nsc 9705
• Pregn-4-ene-3,20-dione, 11,21-dihydroxy-, (11β)-
• Reichstein's substance H
• Corticosterone
• 11BETA,21-DIHYDROXY-4-PREGNENE-3,20-DIONE
• KENDALL'S 'B'
• 11,12-dihydroxyprogesterone
• 4-PREGNENE-11BETA,21-DIOL-3,20-DIONE
• 11,21-Dihydroxypregn-4-ene-3,20-dione
• 11BETA,21-DIHYDROXYPREGN-4-ENE-3,20-DIONE
• 4-PREGNEN-11B,21-DIOL-3,20-DIONE
• 11BETA,21-DIHYDROXY-PROGESTERONE
• 4-PREGNEN-11-BETA, 21-DIOL-3,20-DIONE
• 11BETA,21-DIHYDROXY-4-PRENENE-3,20-DIONE

Corticosterone

CAS: 50-22-6

Formula: C₂₁H₃₀O₄

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 346.47

Ref: 3B-C0388

(11β)-11,21-Dihydroxypregn-4-ene-3,20-dione

CAS: 50-22-6

Formula: C₂₁H₃₀O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 346.4605

Ref: IN-DA0037RK

Corticosterone

CAS: 50-22-6

Corticosterone

Purity: ≥95%

Molecular weight: 346.46g/mol

Ref: 54-BUP14865

Corticosterone

CAS: 50-22-6

Formula: C₂₁H₃₀O₄

Color and Shape: White To Off-White Solid

Molecular weight: 346.47

Ref: 4Z-C-1045

Corticosterone

Controlled Product

CAS: 50-22-6

Formula: C₂₁H₃₀O₄

Color and Shape: Neat

Molecular weight: 346.46

Ref: 04-C11705000

Corticosterone

CAS: 50-22-6

Color and Shape: Neat

Ref: LP-COR-1628-10

Corticosterone 100 µg/mL in Acetonitrile

Controlled Product

CAS: 50-22-6

Formula: C₂₁H₃₀O₄

Color and Shape: Single Solution

Molecular weight: 346.46

Ref: 04-A11705000AL-100

Corticosterone

CAS: 50-22-6

Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active.

Formula: C₂₁H₃₀O₄

Purity: 98.44% - ≥95%

Color and Shape: Solid

Molecular weight: 346.46

Ref: TM-T0948L

Corticosterone

CAS: 50-22-6

Formula: C₂₁H₃₀O₄

Purity: ≥ 97.0%

Color and Shape: White to off-white powder

Molecular weight: 346.46

Ref: 7W-GP3184

Corticosterone-d8

CAS: 50-22-6

Formula: C₂₁H₂₂O₄D₈

Molecular weight: 354.52

Ref: 4Z-C-1041

11-Deoxy Corticosterone-d9

CAS: 50-22-6

Formula: C₂₁H₂₁D₉O₂

Molecular weight: 323.52

Ref: 4Z-C-10415

Corticosterone

Controlled Product

CAS: 50-22-6

Applications Glucocorticoid; an intermediate in the biosynthesis of aldosterone, isolated from the adrenal cortex.
References Schmidt, M., et al.: Endocrinol., 150, 2709 (2009), Bailey, M., et al.: J. Immunol., 182, 7888 (2009), Brunton, P., et al.: J. Neurosci., 29, 6449 (2009), Pruett, S., et al.: Toxicol. Sci., 109, 265 (2009),

Formula: C₂₁H₃₀O₄

Color and Shape: Neat

Molecular weight: 346.46

Ref: TR-C695700

Corticosterone

Controlled Product

CAS: 50-22-6

Steroid hormone produced by adrenal glands

Formula: C₂₁H₃₀O₄

Purity: (Hplc) Min. 98.0%

Color and Shape: White Off-White Powder

Molecular weight: 346.46 g/mol

Ref: 3D-FC20555

Corticosterone

CAS: 50-22-6

Formula: C₂₁H₃₀O₄

Purity: 98%

Color and Shape: Solid, White to slightly pale yellow powder

Molecular weight: 346.467

Ref: 10-F235820

Corticosterone-13C3

Controlled Product

CAS: 50-22-6

Formula: C₃C₁₈H₃₀O₄

Color and Shape: Neat

Molecular weight: 349.438

Ref: TR-C695703

Corticosterone, 1mg/ml in Methanol

CAS: 50-22-6

Color and Shape: Single Solution

Ref: LP-COR-1628-1LM