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CAS 50-24-8

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Prednisolone

Description:
Prednisolone is a synthetic glucocorticoid, primarily used for its anti-inflammatory and immunosuppressive properties. It is characterized by its steroid structure, which includes a cyclopentanoperhydrophenanthrene core, modified with various functional groups that enhance its therapeutic efficacy. Prednisolone is typically administered in the form of tablets, syrups, or injections, and is commonly prescribed for conditions such as asthma, allergies, autoimmune diseases, and certain types of cancer. Its mechanism of action involves binding to glucocorticoid receptors, leading to the modulation of gene expression and a subsequent reduction in inflammation and immune response. Prednisolone exhibits a relatively high bioavailability and is metabolized primarily in the liver, with its effects lasting several hours to days, depending on the dosage and route of administration. While effective, it can also lead to side effects, particularly with long-term use, including weight gain, osteoporosis, and increased susceptibility to infections. As with any medication, it is essential to use prednisolone under medical supervision to manage potential risks and benefits effectively.
Formula:C21H28O5
InChI:InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
InChI key:InChIKey=OIGNJSKKLXVSLS-VWUMJDOOSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)C=C4)([C@@H](O)C1)[H])[H])(CC[C@@]2(C(CO)=O)O)[H]
Synonyms:
  • (11Beta)-11,17-Dihydroxy-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
  • (11β)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
  • 1,2-Dehydrohydrocortisone
  • 1,4-Pregnadiene-11β,17α,21-triol-3,20-dione
  • 1,4-Pregnadiene-3,20-dione-11β,17α,21-triol
  • 1-Dehydrohydrocortisone
  • 11,17,21-Trihydroxypregna-1,4-Diene-3,20-Dione
  • 11-Beta,17-Alpha,21-Trihydroxypregna-1,4-Diene-3,20-Dione
  • 11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione
  • 11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione
  • See more synonyms
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products per page.Found 24 products.
  • Prednisolone

    CAS:
    Purity:97%
    Molecular weight:360.45001220703125

    Ref: 10-F787580

    1g
    46.00€
    5g
    96.00€
    500mg
    To inquire
  • Prednisolone

    Controlled Product
    CAS:
    <p>Prednisolone is a synthetic corticosteroid, which is a derivative of the natural hormone cortisol. It is derived from the modification of the corticosteroid structure to enhance its anti-inflammatory and immunosuppressive properties. The mode of action of prednisolone involves binding to glucocorticoid receptors, leading to the modulation of gene expression. This results in the suppression of pro-inflammatory cytokines and the inhibition of various immune responses.</p>
    Formula:C21H28O5
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:360.44 g/mol

    Ref: 3D-FP27131

    5g
    233.00€
    10g
    341.00€
    25g
    486.00€
    50g
    748.00€
    100g
    1,084.00€
  • Prednisolone (1 mg/mL in Methanol)

    Controlled Product
    CAS:
    Formula:C21H28O5
    Color and Shape:Colourless
    Molecular weight:360.44

    Ref: TR-KIT8255

    10x1ml
    341.00€
  • 11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione

    CAS:
    Formula:C21H28O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:360.4440

    Ref: IN-DA0038OS

    1g
    Discontinued
    5g
    Discontinued
    25g
    Discontinued
    Discontinued product