CAS 50-41-9

Clostilbegit

Description:

Clostilbegit, also known as clomiphene citrate, is a non-steroidal fertility medication primarily used to treat ovulatory dysfunction in women. It acts as a selective estrogen receptor modulator (SERM), influencing the hypothalamic-pituitary-gonadal axis to stimulate ovulation. Clostilbegit is characterized by its ability to bind to estrogen receptors, thereby blocking the negative feedback of estrogen on the hypothalamus, which leads to increased secretion of gonadotropins (LH and FSH) from the pituitary gland. This promotes ovarian follicle development and ovulation. The substance is typically administered orally and is known for its relatively low side effect profile, although it can cause symptoms such as hot flashes, mood swings, and ovarian hyperstimulation in some cases. Clostilbegit is often prescribed in cycles and is considered a first-line treatment for women experiencing infertility due to anovulation. Its chemical structure includes a triphenylethylene backbone, contributing to its unique pharmacological properties. As with any medication, it is essential to use Clostilbegit under medical supervision to monitor for efficacy and potential adverse effects.

Formula: C₂₆H₂₈ClNO·C₆H₈O₇

InChI: InChI=1S/C26H28ClNO.C6H8O7/c1-3-28(4-2)19-20-29-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-18H,3-4,19-20H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key: InChIKey=PYTMYKVIJXPNBD-UHFFFAOYSA-N

SMILES: C(=C(Cl)C1=CC=CC=C1)(C2=CC=C(OCCN(CC)CC)C=C2)C3=CC=CC=C3.C(CC(O)=O)(CC(O)=O)(C(O)=O)O

Synonyms:

• 1-[p-(β-Diethylaminoethoxy)phenyl]-1,2-diphenyl-2-chloroethylene citrate
• 2-(4-(2-Chloro-1,2-diphenylvinyl)phenoxy)-N,N-diethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate
• 2-(4-[2-Chloro-1,2-diphenylethenyl]phenoxy)-N,N-diethylethanamine citrate
• 2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate (1:1)
• 2-[p-(2-Chloro-1,2-diphenylvinyl)phenoxy]triethylamine dihydrogen citrate
• 2-{4-[(E)-2-chloro-1,2-diphenylethenyl]phenoxy}-N,N-diethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate (salt)
• 2-{4-[(Z)-2-chloro-1,2-diphenylethenyl]phenoxy}-N,N-diethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate (salt)
• Chloramiphene
• Clomephene Citrate
• Clomhexal
• Clomid
• Clomifene Citrate
• Clomifeno
• Clomiphene Citrate
• Clomiphene dihydrogen citrate
• Clomivid
• Clomphid
• Clostilbegit
• Clostilbegyt
• Dyneric
• Ethanamine, 2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
• Fertivet
• Fertyl
• Genozym
• Ikaclomin
• Ikaclomine
• Klomen
• Mer 41
• Mrl 41
• NSC 35770
• Omifin
• Pergotime
• Racemic clomiphene citrate
• Serophene
• Siphene
• Triethylamine, 2-[p-(2-chloro-1,2-diphenylvinyl)phenoxy]-, citrate

Clomiphene citrate

CAS: 50-41-9

A selective estrogen receptor modulator

Formula: C₂₆H₂₈ClNO·C₆H₈O₇

Molecular weight: 598.08

Ref: 02-J63663

Clomiphene Citrate

CAS: 50-41-9

Aromatic drugs of amino-alcohols, other than those contg more than one kind of oxygen function, their ethers and esters; salts thereof, nesoi

Formula: C₂₆H₂₈ClNO·C₆H₈O₇

Color and Shape: White Powder

Molecular weight: 597.21294

Ref: 45-1140000

Clomiphene citrate

CAS: 50-41-9

Clomiphene citrate (NSC 35770) is a selective estrogen receptor modulator.

Formula: C₃₂H₃₆ClNO₈

Purity: 98.67% - >99.99%

Color and Shape: White Crystalline Powder

Molecular weight: 598.1

Ref: TM-T1193

Ethanamine, 2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethyl-,2-hydroxy-1,2,3-propanetricarboxylate (1:1)

CAS: 50-41-9

Formula: C₃₂H₃₆ClNO₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 598.0831

Ref: IN-DA00I8WW

Clomiphene Citrate (Mixture of Z and E Isomers)

CAS: 50-41-9

Formula: C₂₆H₂₈ClNO·C₆H₈O₇

Color and Shape: White To Off-White Solid

Molecular weight: 405.97 192.12

Ref: 4Z-C-8223

Clomiphene citrate

Controlled Product

CAS: 50-41-9

Formula: C₂₆H₂₈ClNO·C₆H₈O₇

Color and Shape: Neat

Molecular weight: 598.08

Ref: 04-C11686500

Clomifene Citrate

CAS: 50-41-9

Color and Shape: Neat

Ref: 61-FOR0650.00

Clomifene Citrate

Controlled Product

CAS: 50-41-9

Formula: C₂₆H₂₈ClNO·C₆H₈O₇

Color and Shape: Neat

Molecular weight: 598.08

Ref: 86-MM0650.00

Clomiphene citrate

CAS: 50-41-9

Formula: C₂₆H₂₈ClNO·C₆H₈O₇

Purity: (HPLC) ≥ 98.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 598.08

Ref: 7W-GP4170

Clomifene Citrate RS

CAS: 50-41-9

Color and Shape: None Solid

Ref: 2K-1051000021

Clomiphene Citrate(cis-trans mixture)

Controlled Product

CAS: 50-41-9

Formula: C₂₆H₂₈ClNO·C₆H₈O₇

Color and Shape: Neat

Molecular weight: 598.08

Ref: TR-C587025

Clomiphene citrate, cis-trans mixture

Controlled Product

CAS: 50-41-9

The racemic mixture of cis-trans isomers of clomiphene citrate The cis-isomer, now termed zuclomiphene, is more estrogenic, while the trans-isomer, presently known as enclomiphene, is relatively anti-estrogenic. The racemic mixture utilized for ovulation induction typically contains 38% zuclomiphene and 62% enclomiphene.

Formula: C₂₆H₂₈ClNO•C₆H₈O₇

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 598.08 g/mol

Ref: 3D-FC20501

CLOMIFENE CITRATE CRS

CAS: 50-41-9

CLOMIFENE CITRATE CRS

Ref: 41-C2320000