CAS 50-45-3

2,3-Dichlorobenzoic acid

Description:

2,3-Dichlorobenzoic acid is an aromatic carboxylic acid characterized by the presence of two chlorine atoms positioned at the 2 and 3 positions on the benzene ring relative to the carboxylic acid group. This compound has a molecular formula of C7H4Cl2O2 and features a relatively low solubility in water, while being more soluble in organic solvents. It typically appears as a white to off-white crystalline solid. The presence of chlorine atoms enhances its reactivity and can influence its biological activity, making it of interest in various chemical syntheses and applications, including herbicides and pharmaceuticals. The compound exhibits moderate acidity due to the carboxylic acid functional group, which can participate in hydrogen bonding. Additionally, 2,3-Dichlorobenzoic acid can undergo various chemical reactions, such as nucleophilic substitutions and esterifications, making it a versatile intermediate in organic synthesis. Safety precautions should be observed when handling this substance, as it may pose environmental and health risks.

Formula: C₇H₄Cl₂O₂

InChI: InChI=1S/C7H4Cl2O2/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3H,(H,10,11)

InChI key: InChIKey=QAOJBHRZQQDFHA-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C(Cl)C(Cl)=CC=C1

Synonyms:

• 2,3-Dichlorbenzoesure
• 2,3-Dichloro-Benzoicaci
• 2,3-Dichlorobenzoate
• 2,3-Dichlorobenzoic
• 2,3-Dichlorobenzoicacid
• Benzoic acid, 2,3-dichloro-
• Rarechem Al Bo 0323
• Timtec-Bb Sbb003641
• 2,3-Dichlorobenzoic acid
• 2,3-Dichorobenzoic acid

2,3-Dichlorobenzoic Acid

CAS: 50-45-3

Formula: C₇H₄Cl₂O₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 191.01

Ref: 3B-D3319

2,3-Dichlorobenzoic acid, 98%

CAS: 50-45-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₄Cl₂O₂

Purity: 98%

Color and Shape: White to cream, Powder and/or Lumps

Molecular weight: 191.01

Ref: 02-A10522

LAMOTRIGINE IMPURITY E CRS

CAS: 50-45-3

LAMOTRIGINE IMPURITY E CRS

Formula: C₇H₄Cl₂O₂

Molecular weight: 191.0115

Ref: 41-Y0001032

Lamotrigine Related Compound B (2,3-dichlorobenzoic acid)

CAS: 50-45-3

Aromatic monocarboxylic acids, their anhydrides, halide

Formula: C₇H₄Cl₂O₂

Color and Shape: Beige Powder

Molecular weight: 189.95883

Ref: 45-1356778

2,3-Dichlorobenzoic acid

CAS: 50-45-3

Formula: C₇H₄Cl₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 191.0115

Ref: IN-DA0037FA

2,3-Dichlorobenzoic acid

CAS: 50-45-3

2,3-Dichlorobenzoic acid

Formula: C₇H₄Cl₂O₂

Purity: ≥95%

Color and Shape: white. fine powder

Molecular weight: 191.01g/mol

Ref: 54-OR10912

Lamotrigine EP Impurity E (Lamotrigine USP Related Compound B)

CAS: 50-45-3

Formula: C₇H₄Cl₂O₂

Color and Shape: White To Off-White Solid

Molecular weight: 191.01

Ref: 4Z-L-018

2,3-Dichlorobenzoic Acid

CAS: 50-45-3

Color and Shape: Neat

Ref: 86-MM0922.05

Lamotrigine EP Impurity E

CAS: 50-45-3

Formula: C₇H₄CI₂O₂

Molecular weight: 191.01

Ref: ST-EA-CP-L10005

2,3-Dichlorobenzoic Acid

Controlled Product

CAS: 50-45-3

Impurity Lamotrigine USP Related Compound B/ Lamotrigine EP Impurity E
Applications 2,3-Dichlorobenzoic Acid (Lamotrigine USP Related Compound B) is the key intermediate for antiepileptic drug Lamotrigine (L173250) and other pharmaceuticals for the treatment of central nervous system (CNS) disorders and disease.
References Liao Q., et al.: JingXi. Huagong., 36, 18 (2006); Qadeer, G., et al.: J. Brazilian. Chem. Soc., 18, 1176 (2007); Pellon, R.F., et al.: Syn. Commun., 37, 1853 (2007); Wang, J.F., et al.: Thermochimica. Acta., 512, 118 (2011);

Formula: C₇H₄Cl₂O₂

Color and Shape: Off-White

Molecular weight: 191.01

Ref: TR-D431950

2,3-Dichlorobenzoic acid

CAS: 50-45-3

2,3-Dichlorobenzoic acid is an organic compound that belongs to the class of carboxylates. It is used as a drug substance in the treatment of mycobacterial infections. 2,3-Dichlorobenzoic acid has been shown to have antimicrobial activity against Mycobacterium tuberculosis and other mycobacteria. The sensitivity index for this compound was determined using a chromatographic method with human erythrocytes as the test organism. 2,3-Dichlorobenzoic acid displays its antibacterial activity by inhibiting protein synthesis and cell division. This drug also forms crystalline solids that are soluble in organic solvents such as chloroform or benzene.

Formula: C₇H₄Cl₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 191.01 g/mol

Ref: 3D-ID58052

2,3-Dichlorobenzoic acid

CAS: 50-45-3

Formula: C₇H₄Cl₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 191.01

Ref: 10-F001164

2,3-Dichlorobenzoic Acid-13C,d3

Controlled Product

CAS: 50-45-3

Applications 2,3-Dichlorobenzoic Acid-13C,d3 is an intermediate in synthesizing Lamotrigine-13C3,d3 (L173253), an isotopically labelled Lamotrigine (L173250), an anticonvulsant. Inhibits glutamate release, possible through inhibition of Sodium, Potassium and Calcium currents. Used in treatment of bipolar depression.
References Miller, A.A., et al.: Epilepsia, 27, 483 (1986); Grunze, et al.: Neuropsychobiology, 38, 131 (1998); Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999)

Formula: CC₆D₃HCl₂O₂

Color and Shape: Neat

Molecular weight: 195.023

Ref: TR-D431951

2,3-Dichlorobenzoic Acid pure, 98%

CAS: 50-45-3

Formula: C₇H₄Cl₂O₂

Purity: min. 98%

Color and Shape: Off-white, Powder, Clear

Molecular weight: 191.04

Ref: SR-91427