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CAS 50-47-5

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Desipramine

Description:
Desipramine is a tricyclic antidepressant primarily used in the treatment of major depressive disorder and certain anxiety disorders. It functions by inhibiting the reuptake of norepinephrine and, to a lesser extent, serotonin, thereby increasing the availability of these neurotransmitters in the synaptic cleft. Desipramine is characterized by its chemical formula C18H22N2 and a molecular weight of approximately 262.39 g/mol. It appears as a white to off-white crystalline powder and is typically administered in oral form. The substance has a relatively long half-life, allowing for once-daily dosing in many cases. Common side effects may include dry mouth, constipation, urinary retention, and sedation, among others. Due to its pharmacological profile, desipramine may not be suitable for individuals with certain pre-existing conditions, and its use should be monitored by healthcare professionals. Additionally, it is important to consider potential interactions with other medications, as desipramine can affect the metabolism of various drugs.
Formula:C18H22N2
InChI:InChI=1S/C18H22N2/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20/h2-5,7-10,19H,6,11-14H2,1H3
InChI key:InChIKey=HCYAFALTSJYZDH-UHFFFAOYSA-N
SMILES:C(CCNC)N1C=2C(CCC=3C1=CC=CC3)=CC=CC2
Synonyms:
  • 10, 11-Dihydro-5-(3'-methylaminopropyl) dibenzo [b,f]-azepine
  • 10,11-Dihydro-5-(3-methylaminopropyl)-5H-dibenz[b,f]azepine
  • 10,11-Dihydro-5-[3-(methylamino)propyl]-5-H-dibenz[b,f]azepine
  • 10,11-Dihydro-N-methyl-5H-dibenz[b,f]azepine-5-propanamine
  • 3-(10,11-Dihydrodibenz(B,F)Azepin-5-Yl)Methylpropylamine
  • 5H-Dibenz[b,f]azepine, 10,11-dihydro-5-[3-(methylamino)propyl]-
  • 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N-methyl-
  • DMI
  • DMI (pharmaceutical)
  • Demethylimipramine
  • See more synonyms
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