CAS 50-49-7
:Imipramine
Description:
Imipramine is a tricyclic antidepressant (TCA) primarily used to treat major depressive disorder and certain anxiety disorders. It functions by inhibiting the reuptake of neurotransmitters, particularly norepinephrine and serotonin, thereby increasing their availability in the synaptic cleft. This mechanism contributes to its antidepressant effects. Imipramine is characterized by its chemical formula C19H24N2 and a molecular weight of approximately 284.4 g/mol. The substance appears as a white to off-white crystalline powder and is soluble in water, alcohol, and chloroform, but has limited solubility in ether. Its pharmacological profile includes sedative properties, which can be beneficial for patients with insomnia associated with depression. However, imipramine may also cause side effects such as dry mouth, constipation, and potential cardiovascular issues, necessitating careful monitoring during treatment. Due to its side effect profile, it is often prescribed with caution, especially in elderly patients or those with pre-existing health conditions. Overall, imipramine remains a significant option in the pharmacotherapy of depression and related disorders.
Formula:C19H24N2
InChI:InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3
InChI key:InChIKey=BCGWQEUPMDMJNV-UHFFFAOYSA-N
SMILES:C(CCN(C)C)N1C=2C(CCC=3C1=CC=CC3)=CC=CC2
Synonyms:- 1-(3-Dimethylaminopropyl)-4,5-dihydro-2,3,6,7-dibenzazepine
- 10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine
- 3-(10,11-Dihydrodibenz(B,F)Azepin-5-Yl)Propyldimethylamine
- 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine
- 5,6-Dihydro-N-[3-(dimethylamino)propyl]-11H-dibenz[b,e]azepine
- 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine
- 5H-Dibenz[b,f]azepine, 5-[3-(dimethylamino)propyl]-10,11-dihydro-
- 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-
- Antideprin
- Berkomine
- Cristalia
- Imipramin
- Imipramina
- Melipramine
- N-(3-Dimethylaminopropyl)-o-iminodibenzyl
- N-(γ-Dimethylaminopropyl)iminodibenzyl
- Nsc 169866
- Org 2463
- Prazepine
- See more synonyms
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Found 9 products.
Imipramine Hydrochloride
CAS:Formula:C19H24N2·HClPurity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:316.87Imipramine (Clomipramine EP Impurity B)
CAS:Formula:C19H24N2Color and Shape:Yellow OilMolecular weight:280.42Imipramine
CAS:Controlled Product<p>Imipramine is a tricyclic antidepressant drug that is used to treat major depressive disorder, anxiety disorders, and chronic pain. Imipramine binds to the α1-acid glycoprotein receptor, which may be due to its ability to inhibit hydrogen bonding interactions with other inhibitor molecules. The rate constant of imipramine binding to the α1-acid glycoprotein receptor is high enough for this drug to have a significant effect on the rate of serotonin reuptake in the brain. Imipramine has been shown to have dna binding activity and can be detected in blood samples.br>br>Imipramine has been shown to cause drug interactions with drugs such as warfarin and other anticoagulants, which are metabolized by cytochrome P450 enzymes. Imipramine also interacts with drugs that are substrates for p-glycoprotein (e.g., digoxin) or CYP2D6 (e</p>Formula:C19H24N2Purity:Min. 95%Molecular weight:280.41 g/molImipramine
CAS:<p>Imipramine (Dimipressin) is a Fascin1 inhibitor with antitumor activity and induces apoptosis.</p>Formula:C19H24N2Purity:99.4%Color and Shape:White To Off-White /Hydrochloride/ SolidMolecular weight:280.41
