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CAS 50-52-2

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Thioridazine

Description:
Thioridazine is an antipsychotic medication primarily used to treat schizophrenia and other psychotic disorders. It belongs to the phenothiazine class of drugs, which are characterized by a three-ring structure containing sulfur and nitrogen atoms. Thioridazine acts primarily as a dopamine antagonist, blocking dopamine receptors in the brain, which helps alleviate symptoms of psychosis. The substance is known for its sedative properties and can also exhibit effects on serotonin receptors. Thioridazine is typically administered orally and is metabolized in the liver, with its effects lasting several hours. However, it is associated with a range of side effects, including sedation, weight gain, and potential cardiovascular issues, such as QT interval prolongation, which can lead to serious heart rhythm disturbances. Due to these risks, its use has become more restricted in recent years. As with any medication, it is essential for patients to be monitored closely by healthcare professionals while on thioridazine therapy.
Formula:C21H26N2S2
InChI:InChI=1/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3
InChI key:InChIKey=KLBQZWRITKRQQV-UHFFFAOYSA-N
SMILES:C(CC1N(C)CCCC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(SC)C3
Synonyms:
  • (.+-.)-Thioridazine
  • 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine
  • 10-[2-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine
  • 10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine
  • 10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-methylsulfanylphenothiazine
  • 2-Methylmercapto-10-[2-N-methyl-2-piperidyl)ethyl]phenothiazine
  • Malloryl
  • Meleril
  • Mellaril S
  • Mellerets
  • See more synonyms
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