CAS 50-55-5
:(-)-Reserpine
Description:
(-)-Reserpine is an indole alkaloid derived from the plant Rauwolfia serpentina, commonly known for its use in traditional medicine and as an antihypertensive agent. It is characterized by its complex structure, which includes a tetracyclic core and a methoxy group. The compound exhibits a chiral center, resulting in its designation as "(-)-Reserpine," indicating its specific enantiomeric form. (-)-Reserpine functions primarily as a monoamine antagonist, influencing neurotransmitter levels in the brain, particularly by inhibiting the uptake of norepinephrine and serotonin. This mechanism contributes to its sedative and antihypertensive effects. The substance is typically administered in its salt form, such as reserpine hydrochloride, and is known for its relatively long half-life. In addition to its therapeutic applications, (-)-Reserpine has been studied for its potential effects on mental health disorders, although its use has declined due to the development of newer medications with fewer side effects. Safety considerations include potential adverse effects such as sedation, gastrointestinal disturbances, and cardiovascular impacts.
Formula:C33H40N2O9
InChI:InChI=1/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/p+1/t18-,22+,24-,27+,28+,31+/m1/s1
InChI key:InChIKey=QEVHRUUCFGRFIF-MDEJGZGSSA-N
SMILES:C(OC)(=O)[C@H]1[C@]2(C[C@@]3(C4=C(C=5C(N4)=CC(OC)=CC5)CCN3C[C@]2(C[C@@H](OC(=O)C6=CC(OC)=C(OC)C(OC)=C6)[C@@H]1OC)[H])[H])[H]
Synonyms:- (3Beta,16Beta,17Alpha,18Alpha,20Alpha)-11,17-Dimethoxy-16-(Methoxycarbonyl)-18-[(3,4,5-Trimethoxybenzoyl)Oxy]Yohimban-4-Ium
- (3Beta,16Beta,17Alpha,18Beta,20Alpha)-11,17-Dimethoxy-16-(Methoxycarbonyl)-18-[(3,4,5-Trimethoxybenzoyl)Oxy]Yohimban-4-Ium
- 11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester
- 3,4,5-Trimethoxybenzoyl methyl reserpate
- 3β,20α-Yohimban-16β-carboxylic acid, 18β-hydroxy-11,17α-dimethoxy- methyl ester 3,4,5-trimethoxybenzoate (ester)
- 3β,20α-Yohimban-16β-carboxylic acid, 18β-hydroxy-11,17α-dimethoxy-, methyl ester, 3,4,5-trimethoxybenzoate
- Anquil
- Apoplon
- Banasil
- Benz[g]indolo[2,3-a]quinolizine, yohimban-16-carboxylic acid deriv.
- Bioserpine
- Carpacil
- Crystoserpine
- Deserpine
- Elserpine
- Ent 50146
- Eserpine
- Eskaserp
- Hiposerpil
- Kitine
- Lemiserp
- Loweserp
- Mayserpine
- Methyl reserpate 3,4,5-trimethoxybenzoate (ester)
- Nsc 237659
- Nsc 59272
- Quiescin
- Rau-sed
- Raucap
- Raulen
- Raunervil
- Raupasil
- Raurine
- Rausedil
- Rausedyl
- Rausingle
- Rauwasedin
- Resercaps
- Resercen
- Reserlor
- Reserpamed
- Reserpex
- Reserpic acid methyl ester 3,4,5-trimethoxybenzoate (ester)
- Reserpil
- Reserpin
- Reserpina
- Reserpine Crystalline
- Reserpine base
- Reserpine,98%
- Reserpoid
- Resine
- Resperine
- Respital
- Restran
- Riserpa
- Rivasin
- Roxinoid
- Sandril
- Sedaraupin
- Sedserp
- Serfin
- Serolfia
- Serp-AFD
- Serpaloid
- Serpanray
- Serpasil
- Serpasil Serpasol
- Serpasil premix
- Serpasol
- Serpate
- Serpen
- Serpentina
- Serpicon
- Serpiloid
- Serpine
- Serpine (pharmaceutical)
- Serpipur
- Sertabs
- Sertina
- T-Serp
- Temposerpine
- Triserpin
- Vio-Serpine
- Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3β,16β,17α,18β,20α)-
- NCI-C50157
- Anguil
- rauwita
- Ascoserpina
- imethoxy-,methylester,3,4,5-trimethoxybenzoate(ester)
- diutensen-r
- 3,20-YohiMban-16-carboxylic acid
- hydroserp
- gamma-Serpine
- serpasilpremix
- Carrserp
- reserpene
- Austrapine
- serpalan
- Rausan
- Helfoserpin
- rcrawastenumberu200
- Hypersine
- chloroserpin-250
- serpazol
- Reserpine (base and/or unspecified salts)
- demi-regroton
- Neoserp
- reser-ar
- Interpina
- RESERPINE(RG)
- YohiMban-16-carboxylicacid, 11,17-diMethoxy-18-[(3,4,5-triMethoxybenzoyl)oxy]-, Methyl ester, (3b,16b,17a,18b,20a)-
- (3β,16β,17α,18β,20α)-
- Purserpine
- Alserin
- 11,17-dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)-yohimban-16-carboxylicaci
- Rautrin
- salutensin
- rolserp
- trichlortensin
- Escaspere
- Alkarau
- Rauserpin-Alk
- oxy-methylester3,4,5-trimethoxybenzoate(ester)
- hydromox-r
- residine
- RESERPINE,USP
- chloroserp-500
- serpyrit
- Raugal
- chloroserpine-500
- reserp
- RESERPINE
- Enipresser
- RESERPINE,REAGENT
- Reserpine (200 mg)
- 11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylicaci
- Raudixoid
- Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-(3,4,5-trimethoxybenzoyl)oxy-, methyl ester, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)-
- serpresan
- Rausedan
- serpone
- Reserpine Standard for LC-MS
- Benazyl
- rezide
- serpasil-apresoline
- reserpidefe
- component of Butiserpazide
- serathide
- METHYL RESERPATE 3,4,5-TRIMETHOXYBENZOIC ACID ESTER
- METHYL RESERPATE
- R-e-s
- rivased
- Methyl reserpate 3,4,5-trimethyloxybenzoic acid
- hydrosine25
- reserfia
- klimanosid
- resedril
- serplexk
- Rauserpine
- Maviserpin
- Rauloydin
- renese-r
- diupres250
- rese-lar
- Carditivo
- serpivite
- Eskaserpine
- serpogen
- reserutin
- hydroserpineplus
- Broserpine
- Rauvlid
- banisil
- l-Carpserp
- mallopress
- ReserpineC33H40N209
- Eberpine
- hydro-reserpine-25
- serfolia
- chloroserp-250
- Eberspine
- metatensin#2
- tri-hydroserpine
- methylreserpate3,4,5-trimethoxybenzoicacid
- serpazil
- hydrochloride#2
- hydrochloride#1
- hydro-fluserpine#1
- recipin
- salutensin-demi
- Rauwipur
- serpazide
- resersana
- regroton
- hydropres50
- salazide-demi
- component of Regroton
- Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-
- component of Renese R
- Rauserpol
- ReserpinePuriss
- reserpanca
- Key-serpine
- Reserpine bp
- Reserpine Vetec(TM) reagent grade
- diurese-r
- diupres500
- ser-a-gen
- reserpal
- ent50146
- Raupoid
- Reserpine, froM Rauvolfia
- Raunorine
- resomine
- (3beta,16beta,17alpha,18beta,20alpha)-methyleste
- hydropine
- hydroserpine#1
- metatensin#4
- RESERPINE BP/USP
- ,methylester,(3beta,16beta,17alpha,18beta,20alpha)-
- hydro-reserpine-50
- Raudiford
- resperin
- Idsoserp
- Rawilid
- Hiserpia
- hiposepil
- YohiMban-16-carboxylic acid
- Neo-antitensol
- RESERPINE, CRYSTALLIZED
- usafcb-27
- serpatone
- serpedin
- hydropres25
- salupres
- Rauwilid
- resiatric
- Neoserfin
- esidrix#2
- Reserbal
- Mephaserpin
- Reserpine,99%
- Hypersil
- reserpur
- hydroserpalan
- H 520
- Resedrex
- resaltex
- resocalm
- rezerpin
- Raumorine
- gilucard
- seominal
- 3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-methyl ester 3,4,5-trimethoxybenzoate (ester)
- serpoid
- RESERPINE extrapure
- Rauwoleaf
- Reserjen
- (3β,16β,17α,18β,20α)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylicacidmethylester
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