CAS 50-57-7

lypressin

Description:

Lypressin, also known as lysine vasopressin, is a synthetic analog of the natural hormone vasopressin, which is involved in regulating water retention in the body and blood pressure. It is characterized by its peptide structure, consisting of a sequence of amino acids that includes lysine in place of arginine, which is found in vasopressin. Lypressin is primarily used in medical applications to treat conditions such as diabetes insipidus and certain types of bleeding disorders. Its mechanism of action involves binding to vasopressin receptors in the kidneys, promoting water reabsorption and concentrating urine. Lypressin is typically administered via injection due to its peptide nature, which limits its effectiveness when taken orally. The substance is known for its relatively short half-life, necessitating careful dosing and monitoring in clinical settings. As with any peptide hormone, potential side effects may include water retention, hypertension, and allergic reactions, highlighting the importance of medical supervision during its use.

Formula: C₄₆H₆₅N₁₃O₁₂S₂

InChI: InChI=1/C46H65N13O12S2/c47-17-5-4-9-29(40(65)52-22-38(51)63)54-45(70)35-10-6-18-59(35)46(71)34-24-73-72-23-28(48)39(64)55-31(20-26-11-13-27(60)14-12-26)43(68)56-32(19-25-7-2-1-3-8-25)42(67)53-30(15-16-36(49)61)41(66)57-33(21-37(50)62)44(69)58-34/h1-3,7-8,11-14,28-35,60H,4-6,9-10,15-24,47-48H2,(H2,49,61)(H2,50,62)(H2,51,63)(H,52,65)(H,53,67)(H,54,70)(H,55,64)(H,56,68)(H,57,66)(H,58,69)/t28-,29-,30-,31-,32-,33-,34-,35-/m0/s1

SMILES: c1ccc(cc1)C[C@H]1C(=N[C@@H](CCC(=N)O)C(=N[C@@H](CC(=N)O)C(=N[C@@H](CSSC[C@@H](C(=N[C@@H](Cc2ccc(cc2)O)C(=N1)O)O)N)C(=O)N1CCC[C@H]1C(=N[C@@H](CCCCN)C(=NCC(=N)O)O)O)O)O)O

Synonyms:

• Vasopressin
• (8-Lysine)vasopressin
• 8-L-Lysine vasopressin
• 8-L-Lysinevasopressin
• Diapid
• L-Cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysylglycinamide cyclic (1-6)-disulfide
• L-Lysine vasopressin
• Lipresina
• Lipressina
• Lypressine
• Lypressinum
• Lysine pitressin
• Lysine vasopressin
• Pitressin
• Postacton
• Syntopressin
• Vasophysin
• Vasopressin-8-lysine
• Vasopressin, 8-L-lysine-
• (Lys8)-Vasopressin
• H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bond)
• Lyspressin
• 1-{[19-Amino-7-(2-Amino-2-Oxoethyl)-10-(3-Amino-3-Oxopropyl)-13-Benzyl-16-(4-Hydroxybenzyl)-6,9,12,15,18-Pentaoxo-1,2-Dithia-5,8,11,14,17-Pentaazacycloicosan-4-Yl]Carbonyl}Prolyllysylglycinamide
• 1-{[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-L-lysylglycinamide
• 1,2-Dithia-5,8,11,14,17-pentaazacycloeicosane-10-propionamide, 19-amino-4-[2-[[5-amino-1-[(carbamoylmethyl)carbamoyl]pentyl]carbamoyl]-1-pyrrolidinylcarbonyl]-13-benzyl-7-(carbamoylmethyl)-16-p-hydroxybenzyl-6,9,12,15,18-pentaoxo-
• 3-(Phenylalanine)-8-lysine oxytocin
• Glycinamide, L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysyl-, cyclic (1→6)-disulfide
• L 8
• Lysine-ADH
• Lysipressin
• Lysopressin
• Lysylvasopressin
• Oxytocin, 3-(L-phenylalanine)-8-L-lysine-

[Lys⁸] Vasopressin

CAS: 50-57-7

For cellular and molecular biology applications

Formula: C₄₆H₆₅N₁₃O₁₂S₂

Color and Shape: Powder, White

Molecular weight: 1056.22

Ref: 02-J66728

(Lys⁸)-Vasopressin

CAS: 50-57-7

A compound with reduced vasopressor and antidiuretic activity, as compared to AVP.

Formula: C₄₆H₆₅N₁₃O₁₂S₂

Purity: > 98%

Color and Shape: White

Molecular weight: 1056.23

Ref: 01-4014772

Lypressin (8-L-lysine vasopressin)

CAS: 50-57-7

Polypeptide, protein and glycoprotein hormones, their derivatives and structural analogues, nesoi

Formula: C₄₆H₆₅N₁₃O₁₂S₂

Color and Shape: White Powder

Molecular weight: 1055.43171

Ref: 45-1711133

Vasopressin, 8-L-lysine-

CAS: 50-57-7

Formula: C₄₆H₆₅N₁₃O₁₂S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 1056.2182

Ref: IN-DA00I8X0

Lysipressin

CAS: 50-57-7

Lysipressin: contracts rabbit bladder, stimulates adenylate cyclase, antidiuretic hormone in pigs/marsupials.

Formula: C₄₆H₆₅N₁₃O₁₂S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 1056.22

Ref: TM-T11918

Terlipressin EP Impurity C Ditrifluoroacetate (Des-(1-3)-Terlipressin Ditrifluoroacetate)

CAS: 50-57-7

Formula: C₄₆H₆₅N₁₃O₁₂S₂·2C₂HF₃O₂

Molecular weight: 1056.23 2*114.02

Ref: 4Z-PT-150005

Lysipressin Acetate

CAS: 50-57-7

Ref: 7W-GX9708

Lysipressin Acetate

CAS: 50-57-7

Formula: C₄₆H₆₅N₁₃O₁₂S₂

Purity: 95%~99%

Color and Shape: White to Off-white Powder

Molecular weight: 1056.22

Ref: BP-BPPG048

Lypressin

CAS: 50-57-7

Lypressin

Formula: C₄₆H₆₅N₁₃O₁₂S₂

Purity: By hplc: >97% (Typical Value in Batch COA)

Color and Shape: white powder

Molecular weight: 1,056.22g/mol

Ref: 54-BITH3033

Lypressin

CAS: 50-57-7

Formula: C₄₆H₆₅N₁₃O₁₂S₂

Molecular weight: 1056.23

Ref: 4Z-PL-180001

Lypressin

CAS: 50-57-7

Lypressin is a synthetic nonapeptide that functions as an analog of the natural hormone vasopressin, which is endogenously produced in the posterior pituitary gland. Its primary mode of action involves binding to vasopressin receptors in the renal collecting ducts, where it promotes water reabsorption, thereby exhibiting antidiuretic effects. Additionally, Lypressin has some vasopressor activity, though it is less potent in this regard compared to natural vasopressin.

Formula: C₄₆H₆₅N₁₃O₁₂S₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 1,056.22 g/mol

Ref: 3D-FL38924

Lysipressin-d5 Trifluoroacetic Acid Salt

Controlled Product

CAS: 50-57-7

Stability Hygroscopic
Applications Isotope labelled Lysipressin (L488770) is an analog of Vasopressin (A769550), a powerful vasopressor used to modulate blood pressure. An endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. It is a neurotransmitter in the central nervous system and also implicated in a variety of physiological processes such as regulating water balance by antidiuretic action.
References Perucca, J. et al.: J. AM. Soc. Nephrol., 19, 1721 (2008); Toba, K. et al.: Prog. Brain Res., 119, 337 (1998); Berrada, K. et al.: J. Biol. Chem., 275, 27229 (2000);

Formula: C₄₆H₆₀D₅N₁₃O₁₂S₂•x(C₂HF₃O₂)

Color and Shape: Neat

Molecular weight: 1061.2511402

Ref: TR-L488773

Lysipressin Acetic Acid Salt

CAS: 50-57-7

Applications Lysipressin Acetic Acid Salt, is an analog of Vasopressin (A769550), a powerful vasopressor used to modulate blood pressure. An endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. It is a neurotransmitter in the central nervous system and also implicated in a variety of physiological processes such as regulating water balance by antidiuretic action.
References Yamashita, K. et al.: Mol. Phylo., 67, 520 (2013); Hua F. et al.: J. Emerg. Med., 44, 434 (2013); Perucca, J. et al.: J. AM. Soc. Nephrol., 19, 1721 (2008); Toba, K. et al.: Prog. Brain Res., 119, 337 (1998); Berrada, K. et al.: J. Biol. Chem., 275, 27229 (2000);

Formula: C₄₆H₆₅N₁₃O₁₂S₂·xC₂H₄O₂

Color and Shape: White Solid

Molecular weight: 1056.23 + (60.05)x

Ref: TR-L488770

Lysipressin-d2 Trifluoroacetic Acid Salt

Controlled Product

CAS: 50-57-7

Applications Isotope labelled Lysipressin (L488770) is an analog of Vasopressin (A769550), a powerful vasopressor used to modulate blood pressure. An endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. It is a neurotransmitter in the central nervous system and also implicated in a variety of physiological processes such as regulating water balance by antidiuretic action.
References Perucca, J. et al.: J. AM. Soc. Nephrol., 19, 1721 (2008); Toba, K. et al.: Prog. Brain Res., 119, 337 (1998); Berrada, K. et al.: J. Biol. Chem., 275, 27229 (2000);

Formula: C₄₆H₆₃D₂N₁₃O₁₂S₂·x(C₂HF₃O₂)

Color and Shape: Neat

Molecular weight: 1058.23 + x(114.02)

Ref: TR-L488772