CAS 5000-65-7

2-Bromo-3′-methoxyacetophenone

Description:

2-Bromo-3′-methoxyacetophenone, with the CAS number 5000-65-7, is an organic compound that belongs to the class of acetophenones. It features a bromine atom and a methoxy group attached to the aromatic ring, which influences its chemical reactivity and physical properties. This compound typically appears as a solid at room temperature and is characterized by its moderate solubility in organic solvents such as ethanol and dichloromethane, while being less soluble in water due to its hydrophobic nature. The presence of the bromine atom enhances its electrophilic character, making it useful in various chemical reactions, including nucleophilic substitutions and coupling reactions. The methoxy group can also participate in electron-donating effects, which can stabilize certain intermediates during chemical transformations. 2-Bromo-3′-methoxyacetophenone is often utilized in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals, due to its versatile reactivity and the ability to serve as a building block for more complex molecules. Safety precautions should be observed when handling this compound, as it may pose health risks.

Formula: C₉H₉BrO₂

InChI: InChI=1/C9H9BrO2/c1-12-8-4-2-3-7(5-8)9(11)6-10/h2-5H,6H2,1H3

InChI key: InChIKey=IOOHBIFQNQQUFI-UHFFFAOYSA-N

SMILES: C(CBr)(=O)C1=CC(OC)=CC=C1

Synonyms:

• 2-Bromo-1-(3-Methoxyphenyl)Ethanone
• 2-Bromo-1-(3-methoxyphenyl)ethan-1-one
• 2-Bromo-1-(3-methoxyphenyl-1-yl)ethanone
• 2-Bromo-1-[3-(methyloxy)phenyl]ethanone
• 2-Bromo-3-methoxyacotophenone
• 2-Bromo-m-methoxyacetophenone
• 3-Methoxyphenacyl bromide
• Acetophenone, 2-bromo-3′-methoxy-
• Bromomethyl 3-Methoxyphenyl Ketone
• Ethanone, 2-bromo-1-(3-methoxyphenyl)-
• NSC 405833
• alpha-Bromo-3-methoxyacetophenone
• m-(Bromoacetyl)anisole
• m-Methoxyphenacyl bromide
• α-Bromo-3′-methoxyacetophenone
• α-Bromo-m-methoxyacetophenone
• ω-Bromo-3-methoxyacetophenone
• 2-BROMO-3''-METHOXYACETOPHENONE 97%
• 2-BROMO-3'-METHOXYACETOPHENONE
• AKOS BBS-00003869
• 3'-Methoxyphenacyl Bromide [for HPLC Labeling]
• 1-(Bromoacetyl)-3-methoxybenzene
• ALPHA-BROMO-M-METHOXYACETOPHENONE

3'-Methoxyphenacyl Bromide

CAS: 5000-65-7

Formula: C₉H₉BrO₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 229.07

Ref: 3B-M0815

3'-Methoxyphenacyl Bromide [for HPLC Labeling]

CAS: 5000-65-7

Formula: C₉H₉BrO₂

Purity: >99.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 229.07

Ref: 3B-A5505

2-Bromo-3'-methoxyacetophenone, 98%

CAS: 5000-65-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₉H₉BrO₂

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder, Pale cream

Molecular weight: 229.07

Ref: 02-A10716

2-Bromo-1-(3-Methoxyphenyl)Ethanone

CAS: 5000-65-7

Formula: C₉H₉BrO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 229.0706

Ref: IN-DA00I8X4

2-Bromo-3''-methoxyacetophenone

CAS: 5000-65-7

Formula: C₉H₉BrO₂

Molecular weight: 229.08

Ref: 7W-GK9179

3-Methoxyphenacyl bromide

CAS: 5000-65-7

3-Methoxyphenacyl bromide

Formula: C₉H₉BrO₂

Purity: 97%

Color and Shape: yellow solid

Molecular weight: 229.07g/mol

Ref: 54-OR8784

2-Bromo-3'-methoxyacetophenone

Controlled Product

CAS: 5000-65-7

Applications Derivatizing reagent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Webster, S., et al.: Bioorg. Med. Chem. Lett., 20, 3265 (2010), Chezal, J., et al.: Eur. J. Med. Chem., 45, 2044 (2010),

Formula: C₉H₉BrO₂

Color and Shape: Neat

Molecular weight: 229.07

Ref: TR-B684800

2-Bromo-3'-methoxyacetophenone

CAS: 5000-65-7

2-Bromo-3'-methoxyacetophenone is a reactive compound that has been used as an antiplatelet drug. It is a prodrug of vicagrel, which inhibits the platelet aggregation by blocking the conversion of ADP to ATP. It also has been shown to inhibit the growth of cryptococcus neoformans. This compound binds to matrix proteins and disrupts their structure, leading to a decrease in platelet adhesion. 2-Bromo-3'-methoxyacetophenone has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The biological properties of this drug are complex and depend on its concentration and duration of exposure. Its effect on platelet aggregation is due to its ability to inhibit the activity of protein kin

Formula: C₉H₉BrO₂

Purity: Min. 95%

Molecular weight: 229.07 g/mol

Ref: 3D-FB19124

3-Methoxyphenacyl bromide

CAS: 5000-65-7

Formula: C₉H₉BrO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 229.073

Ref: 10-F018069