CAS 500170-27-4

d[Cha4]-AVP

CAS: 500170-27-4

Potent human V1B vasopressin receptor agonist; Ki: V1B=1.2 nM; increases ACTH, corticosterone; low vasopressor effect.

Formula: C₅₀H₇₁N₁₃O₁₁S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 1094.31

Ref: TM-TP2082

(Deamino-Cys1,b-cyclohexyl-Ala4,Arg8)-Vasopressin trifluoroacetate salt

CAS: 500170-27-4

Desmopressin is a synthetic analogue of vasopressin, which is used to treat disorders associated with insufficient secretion of vasopressin. It has been shown that desmopressin binds to the vasopressin V2 receptor subtype and stimulates the release of arginine-vasopressin in corticotropin-releasing hormone (CRH)-treated rat pituitary cells. This stimulation was mediated by a residue on the Cys1,b-cyclohexyl residue. The binding of desmopressin to this site was demonstrated in vitro using binding experiments on rat brain synaptosomes. Desmopressin has also been shown to stimulate ovulation in rats and humans, and it has been shown to be effective for treating nocturnal enuresis in children.

Formula: C₅₀H₇₁N₁₃O₁₁S₂

Purity: Min. 95%

Molecular weight: 1,094.31 g/mol

Ref: 3D-FD109768