CAS 500579-04-4

2,2′-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine]

Description:

2,2′-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine], identified by CAS number 500579-04-4, is a synthetic organic compound characterized by its complex molecular structure, which includes a pyrimidine core and multiple aromatic amine functionalities. This compound typically exhibits properties such as moderate solubility in organic solvents and potential bioactivity, making it of interest in medicinal chemistry. Its structure suggests the presence of multiple functional groups, which may contribute to its reactivity and interactions with biological targets. The presence of pyridine and dimethylamino groups indicates potential for hydrogen bonding and electronic interactions, which can influence its pharmacological properties. Additionally, the compound may exhibit specific optical characteristics, depending on its conformation and substituents. Overall, this substance is likely to be studied for its potential applications in drug development or as a chemical probe in biological research.

Formula: C₂₇H₃₅N₅

InChI: InChI=1S/C27H35N5/c1-29(2)25-12-7-5-10-23(25)20-31-18-9-19-32(27(31)22-14-16-28-17-15-22)21-24-11-6-8-13-26(24)30(3)4/h5-8,10-17,27H,9,18-21H2,1-4H3

InChI key: InChIKey=KVQOGDQTWWCZFX-UHFFFAOYSA-N

SMILES: C(N1C(N(CC2=C(N(C)C)C=CC=C2)CCC1)C=3C=CN=CC3)C4=C(N(C)C)C=CC=C4

Synonyms:

• 2,2′-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine]
• 2-[[3-[[2-(Dimethylamino)phenyl]methyl]-2-pyridin-4-yl-1,3-diazinan-1-yl]methyl]-N,N-dimethylaniline
• Benzenamine, 2,2′-[[dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethyl-
• NSC 136476
• GANT 61

GANT 61(NSC 136476)

CAS: 500579-04-4

Formula: C₂₇H₃₅N₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 429.6003

Ref: IN-DA006WD4

GANT 61

CAS: 500579-04-4

GANT 61

Purity: ≥95%

Molecular weight: 429.6g/mol

Ref: 54-BUP13069

2,2'-[[Dihydro-2-(4-Pyridinyl)-1,3(2H,4H)-Pyrimidinediyl]Bis(Methylene)]Bis[N,N-Dimethylbenzenamine

CAS: 500579-04-4

2,2'-[[Dihydro-2-(4-Pyridinyl)-1,3(2H,4H)-Pyrimidinediyl]Bis(Methylene)]Bis[N,N-Dimethylbenzenamine

Purity: 98%

Molecular weight: 429.61g/mol

Ref: 54-OR1025625

GANT61

CAS: 500579-04-4

Formula: C₂₇H₃₅N₅

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 429.6

Ref: 7W-GL7283

GANT 61

CAS: 500579-04-4

GANT 61 (GANT61) is an inhibitor for Gli1 and Gli2.

Formula: C₂₇H₃₅N₅

Purity: 97.59% - >99.99%

Color and Shape: Solid

Molecular weight: 429.6

Ref: TM-T3070

GANT61

Controlled Product

CAS: 500579-04-4

Applications GANT61 is an inhibitor for GLI1 as well as GLI2-induced transcription, inhibits hedgehog, displays selectivity over other pathways, such as TNF and glucocorticoid receptor gene transactivation.
References Lauth, M., et al.: Proc. Natl. Acad. Sci., 104, 8455 (2007); Desch, P., et al.: Oncogene, 29, 4885 (2010); Mazumdar, Y., et al.: Cancer Res., 71, 1092 (2011)

Formula: C₂₇H₃₅N₅

Color and Shape: Neat

Molecular weight: 429.6

Ref: TR-G245100

GANT 61

CAS: 500579-04-4

Inhibitor of transcription activator of the Hedgehog pathway Gli

Formula: C₂₇H₃₅N₅

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 429.6 g/mol

Ref: 3D-FG137676