CAS 5006-64-4

α-Fluoro-β-ureidopropionic acid

Description:

α-Fluoro-β-ureidopropionic acid, with the CAS number 5006-64-4, is an organic compound characterized by the presence of both a fluoro group and a ureido functional group within its molecular structure. This compound typically exhibits properties associated with amino acids, given its ureido and carboxylic acid functionalities. It is a white crystalline solid that is soluble in water, which is a common trait for many amino acid derivatives. The presence of the fluorine atom can influence its reactivity and biological activity, potentially enhancing its interaction with biological systems. α-Fluoro-β-ureidopropionic acid may be of interest in pharmaceutical research, particularly in the development of new drugs or as a biochemical probe due to its unique structural features. Additionally, its synthesis and characterization are important for understanding its potential applications in medicinal chemistry and biochemistry. As with many fluorinated compounds, it may exhibit distinct properties compared to its non-fluorinated counterparts, making it a subject of interest in various chemical studies.

Formula: C₄H₇FN₂O₃

InChI: InChI=1S/C4H7FN2O3/c5-2(3(8)9)1-7-4(6)10/h2H,1H2,(H,8,9)(H3,6,7,10)

InChI key: InChIKey=FKTHAKABFGARQH-UHFFFAOYSA-N

SMILES: C(CNC(N)=O)(C(O)=O)F

Synonyms:

• 2-Fluoro-3-ureidopropanoic acid
• 2-Fluoro-3-ureidopropionic acid
• 3-[(Aminocarbonyl)amino]-2-fluoropropanoic acid
• N-Carbamoyl-2-fluoro-β-alanine
• Propanoic Acid, 3-[(Aminocarbonyl)Amino]-2-Fluoro-
• α-Fluoro-β-ureidopropionic acid
• β-Alanine, N-carbamoyl-2-fluoro-
• 3-(Carbamoylamino)-2-fluoropropanoic acid

N-Carbamoyl-2-fluoro-β-alanine

CAS: 5006-64-4

Molecular weight: 150.11

Ref: 7W-GM7221

Fluorouracil Impurity 4

CAS: 5006-64-4

Formula: C₄H₇FN₂O₃

Molecular weight: 150.11

Ref: 4Z-F-5313

N-Carbamoyl-2-fluoro-(β)-alanine

Controlled Product

CAS: 5006-64-4

Applications A metabolite of Capecitabine.
References Arellano, M., ET AL.: Br. J. Cancer, 77, 79 (1998), Budman, D., ET AL.: J. Clin. Oncol., 16, 1795 (1998), Khanna, R., et al.: Cancer Res., 60, 4725 (2000), Charasson, V., et al.: Drug Metab. Dispos., 30, 731 (2002),

Formula: C₄H₇FN₂O₃

Color and Shape: Neat

Molecular weight: 150.11

Ref: TR-C175870

N-Carbamoyl-2-fluoro-β-alanine

CAS: 5006-64-4

N-Carbamoyl-2-Fluoro-beta-Alanine is an oral prodrug that is converted to the active form, N-carbamoyl-2,6-difluoro-beta-alanine (DFDFA), in vivo. It has shown efficacy against tumor cells in a model system and has been tested as a chemotherapeutic agent in vivo. The mechanism of action of DFDFA is not fully understood, but it may involve inhibition of protein synthesis and nucleic acid synthesis. DFDFA also has potential for use as a vaccine adjuvant for tularemia and maternal blood studies.

Formula: C₄H₇FN₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 150.11 g/mol

Ref: 3D-FC80951