CAS 500799-61-1

Abz-Phe-Arg-Lys(Dnp)-Pro-Oh

Description:

The chemical substance "Abz-Phe-Arg-Lys(Dnp)-Pro-Oh," with the CAS number 500799-61-1, is a synthetic peptide that features a specific sequence of amino acids. The abbreviation "Abz" refers to 2-aminobenzoic acid, which is often used as a fluorescent label or chromophore in peptide synthesis. The sequence includes phenylalanine (Phe), arginine (Arg), lysine (Lys) with a dinitrophenyl (Dnp) modification, proline (Pro), and a hydroxyl group (Oh) at the terminal end. This peptide is typically utilized in biochemical research, particularly in studies involving enzyme activity, peptide interactions, and as a substrate in various assays. The presence of the Dnp group can enhance the peptide's stability and facilitate detection in analytical methods. Overall, this compound exemplifies the complexity of peptide design, allowing for specific interactions and functionalities in biological systems. Its unique structure and modifications make it a valuable tool in the fields of biochemistry and molecular biology.

Abz-Phe-Arg-Lys(Dnp)-Pro-OH

CAS: 500799-61-1

Excellent angiotensin I-converting enzyme (ACE) FRET substrate with a Km value of 4.0 µM and a kcat value of 210 s⁻¹. Alves et al. developed a continuous fluorescent assay using Abz-FRK(Dnp)P for the determination of ACE activity in plasma and tissue.

Formula: C₃₉H₄₉N₁₁O₁₀

Purity: > 98%

Color and Shape: White Powder

Molecular weight: 831.89

Ref: 01-4043877

Abz-FR-K(Dnp)-P-OH

CAS: 500799-61-1

Excellent angiotensin I-converting enzyme (ACE) substrate with a Km value of 4.0 μM and a kcat value of 210s-1.

Formula: C₃₉H₄₉N₁₁O₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 831.87

Ref: TM-TP1682

Abz-frk(dnp)-P

CAS: 500799-61-1

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₃₉H₄₉N₁₁O₁₀

Molecular weight: 831.4 g/mol

Ref: 3D-PP49955

Abz-Phe-Arg-Lys(Dnp)-Pro-OH trifluoroacetate

CAS: 500799-61-1

Abz-Phe-Arg-Lys(Dnp)-Pro-OH trifluoroacetate (ABA) is a low potency activator of the endogenous angiotensin system, with no known clinical use. ABA has been shown to activate the endogenous angiotensin system in vivo in rats and humans. It has also been shown to increase blood pressure in rats by activating the renal sympathetic nervous system. The activation of this system may be due to its ability to release neutrophil chemotactic factor from adipose tissue, increasing the number of neutrophils that contribute to inflammation through their release of reactive oxygen species. The mechanism underlying this activation is unknown, but may involve an interaction with enalaprilat, a potent inhibitor of angiotensin converting enzyme (ACE), or adipose tissue lipolysis.

Formula: C₃₉H₄₉N₁₁O₁₀•(C₂HF₃O₂)x

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 831.87 g/mol

Ref: 3D-FA110981