CAS 5011-34-7

Trimetazidine

Description:

Trimetazidine is a pharmaceutical compound primarily used as an antianginal agent, particularly in the treatment of stable angina pectoris. It functions by optimizing cellular metabolism, enhancing glucose utilization, and improving energy production in ischemic heart tissues. The chemical formula of trimetazidine is C₁₄H₁₈N₂S, and it features a thiazole ring, which is integral to its mechanism of action. Trimetazidine is known for its ability to reduce the frequency of angina attacks and improve exercise tolerance without affecting heart rate or blood pressure significantly. It is typically administered orally and is well-absorbed in the gastrointestinal tract. The compound is generally well-tolerated, with a low incidence of side effects, although some patients may experience gastrointestinal disturbances or dizziness. Due to its metabolic effects, trimetazidine is sometimes used off-label in other conditions, such as tinnitus and vertigo. However, its use should be guided by a healthcare professional, considering potential contraindications and interactions with other medications.

Formula: C₁₄H₂₂N₂O₃

InChI: InChI=1S/C14H22N2O3/c1-17-12-5-4-11(13(18-2)14(12)19-3)10-16-8-6-15-7-9-16/h4-5,15H,6-10H2,1-3H3

InChI key: InChIKey=UHWVSEOVJBQKBE-UHFFFAOYSA-N

SMILES: C(C1=C(OC)C(OC)=C(OC)C=C1)N2CCNCC2

Synonyms:

• 1-(2,3,4-Trimethoxybenzyl)Piperazine
• 1-[(2,3,4-Trimethoxyphenyl)methyl]piperazine
• 4-(2,3,4-Trimethoxybenzyl)piperazine
• Piperazine, 1-(2,3,4-trimethoxybenzyl)-
• Piperazine, 1-[(2,3,4-trimethoxyphenyl)methyl]-
• Preductal
• Preductal MB
• Trimetazidine ( base and/or unspecified salts)
• Trimetazidine (TMZ)
• Vasorel
• Trimetazidine

Trimetazidine

CAS: 5011-34-7

Formula: C₁₄H₂₂N₂O₃

Molecular weight: 266.34

Ref: 7W-GP6819

Trimetazidine

CAS: 5011-34-7

Trimetazidine is a antianginal agent that selectively inhibits the mitochondrial enzyme LC 3-KAT, thereby preventing β-oxidation of free fatty acids.

Formula: C₁₄H₂₂N₂O₃

Purity: 99.9%

Color and Shape: Hite Or Off-White Crystalline Powder

Molecular weight: 266.34

Ref: TM-T22444

1-(2,3,4-Trimethoxy-benzyl)-piperazine

CAS: 5011-34-7

Purity: 95.0%

Color and Shape: Liquid, Viscous

Molecular weight: 266.34100341796875

Ref: 10-F029299

1-(2,3,4-Trimethoxybenzyl)piperazine

Controlled Product

CAS: 5011-34-7

Applications 1-(2,3,4-trimethoxybenzyl)piperazine (cas# 5011-34-7) is a useful research chemical.

Formula: C₁₄H₂₂N₂O₃

Color and Shape: Neat

Molecular weight: 266.336

Ref: TR-B589308

Trimetazidine

Controlled Product

CAS: 5011-34-7

Trimetazidine is a potent anti-ischemic and anti-anginal agent that has been shown to inhibit apoptosis in human cell lines. It acts as a kinase inhibitor, modulating the activity of various enzymes involved in cell cycle regulation and protein synthesis. Trimetazidine has been found to be an effective analog for the treatment of tumors, acting as an inhibitor of tumor cell growth and inducing apoptosis in cancer cells. Additionally, it has been shown to reduce the risk of urinary tract infections in patients undergoing chemotherapy. Overall, Trimetazidine is a promising anticancer agent with potential therapeutic applications.

Formula: C₁₄H₂₂N₂O₃

Purity: Min. 95%

Molecular weight: 266.34 g/mol

Ref: 3D-FAA01134