CAS 501121-34-2

[(3S,5S)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]-3,5-dihydroxy-heptanoyl]oxysodium

Description:

The chemical substance with the name "[(3S,5S)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]-3,5-dihydroxy-heptanoyl]oxysodium" and CAS number 501121-34-2 is a complex organic compound characterized by its specific stereochemistry and functional groups. It features a pyrrole ring, which is a five-membered aromatic heterocycle, and incorporates multiple substituents, including a fluorophenyl group and a phenylcarbamoyl moiety. The presence of hydroxyl groups indicates potential for hydrogen bonding, which may influence its solubility and reactivity. The sodium salt form suggests that it is likely soluble in water, enhancing its bioavailability for pharmaceutical applications. This compound may exhibit biological activity due to its structural complexity and the presence of various functional groups, making it a candidate for further investigation in medicinal chemistry. Its stereochemistry, particularly the (3S,5S) configuration, is crucial for its interaction with biological targets, potentially affecting its pharmacodynamics and pharmacokinetics.

Formula: C₃₃H₃₄FN₂NaO₅

InChI: InChI=1/C33H35FN2O5.Na/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);/q;+1/p-1/t26-,27-;/m0./s1

SMILES: CC(C)c1c(c(c2ccccc2)c(c2ccc(cc2)F)n1CCC(CC(CC(=O)O)O)O)C(=Nc1ccccc1)O.[Na]

Synonyms:

• S,S-Atorvastatin

ATORVASTATIN IMPURITY MIXTURE CRS

CAS: 125995-03-1, 501121-34-2

ATORVASTATIN IMPURITY MIXTURE CRS

Ref: 41-Y0002310

Atorvastatin EP Impurity E (Atorvastatin USP Related Compound E (Free Form), ent-Atorvastatin)

CAS: 501121-34-2

Formula: C₃₃H₃₅FN₂O₅

Molecular weight: 558.65

Ref: 4Z-A-1220

(3S,5S)-Atorvastatin

CAS: 501121-34-2

ent-Atorvastatin is a selective and competitive inhibitor of HMGCR (HMG-CoA reductase).

Formula: C₃₃H₃₅FN₂O₅

Color and Shape: Solid

Molecular weight: 558.65

Ref: TM-T21080

(3S,5S)-Atorvastatin sodium salt

CAS: 501121-34-2

Atorvastatin is a statin drug that inhibits the enzyme HMG-CoA reductase, which is responsible for cholesterol synthesis. Atorvastatin is used to lower LDL cholesterol and total cholesterol levels in the blood. It also lowers triglyceride levels and raises HDL cholesterol levels. Atorvastatin has been shown to inhibit fibrinogen production, reduce TNF-α production, and improve body mass index (BMI) in obese patients. This drug has been shown to be effective in reducing the size of atherosclerotic lesions by decreasing the amount of cholesteryl esters transferred from high-density lipoprotein (HDL) to low-density lipoprotein (LDL). It has also been shown to inhibit collagen production and stimulate muscle cell proliferation.

Formula: C₃₃H₃₄FN₂NaO₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 580.62 g/mol

Ref: 3D-IA18023