CAS 501373-87-1

(R)-Hydroxy Iloperidone

Description:

(R)-Hydroxy Iloperidone is a chemical compound that serves as a derivative of iloperidone, an atypical antipsychotic medication primarily used in the treatment of schizophrenia. This compound is characterized by its chiral nature, with the "(R)" designation indicating its specific stereochemistry, which can influence its pharmacological properties and interactions within biological systems. The molecular structure includes a hydroxyl group, which contributes to its solubility and reactivity. As a member of the butyrophenone class, (R)-Hydroxy Iloperidone exhibits affinity for various neurotransmitter receptors, particularly dopamine and serotonin receptors, which are crucial in modulating mood and behavior. Its pharmacokinetic profile, including absorption, distribution, metabolism, and excretion, is essential for understanding its therapeutic efficacy and safety. Research into this compound may focus on its potential benefits in psychiatric treatment, as well as its side effect profile compared to other antipsychotics. Overall, (R)-Hydroxy Iloperidone represents a significant area of interest in medicinal chemistry and psychopharmacology.

Formula: C₂₄H₂₉FN₂O₄

Synonyms:

• (1R)-1-[4-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy]-3-methoxyphenyl]ethanol
• Iloperidone Impurity 16
• (R)-Hydroxy Iloperidone
• Iloperidone (R)-Hydroxy Impurity

(R)-Hydroxy Iloperidone-d3

Controlled Product

CAS: 501373-87-1

Formula: C₂₄D₃H₂₆FN₂O₄

Color and Shape: Neat

Molecular weight: 431.515

Ref: TR-H943232

(R)-Hydroxy Iloperidone

Controlled Product

CAS: 501373-87-1

Applications Metabolite of Iloperidone (I267200), a combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Antipsychotic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sainati, S.M., et al.: J. Clin. Pharmacol., 35, 713 (1995), Szewczak, M.R., et al.: J. Pharmacol. Exp. Ther., 274, 1404 (1995), Kongsamut, S., et al.: Eur. J. Pharmacol., 317, 417 (1996),

Formula: C₂₄H₂₉FN₂O₄

Color and Shape: Neat

Molecular weight: 428.497

Ref: TR-H943230

(R)-Hydroxy Iloperidone

CAS: 501373-87-1

Formula: C₂₄H₂₉FN₂O₄

Molecular weight: 428.5

Ref: ST-EA-CP-I38002