CAS 501925-31-1

N-(5-Chloro-2,4-dimethoxyphenyl)-N′-(5-methyl-3-isoxazolyl)urea

Description:

N-(5-Chloro-2,4-dimethoxyphenyl)-N′-(5-methyl-3-isoxazolyl)urea, with the CAS number 501925-31-1, is a chemical compound that belongs to the class of ureas. This substance features a complex molecular structure characterized by the presence of a chloro-substituted aromatic ring and an isoxazole moiety, which contributes to its unique chemical properties. The dimethoxy groups enhance its solubility and reactivity, while the isoxazole ring may impart specific biological activities. Typically, compounds of this nature are investigated for their potential applications in pharmaceuticals, particularly in the development of agrochemicals or as therapeutic agents. The presence of halogen and heterocyclic structures often influences the compound's interaction with biological targets, making it a subject of interest in medicinal chemistry. As with many organic compounds, its stability, solubility, and reactivity can vary based on environmental conditions and the presence of other substances. Safety data and handling precautions should be consulted when working with this compound, as with any chemical substance.

Formula: C₁₃H₁₄ClN₃O₄

InChI: InChI=1S/C13H14ClN3O4/c1-7-4-12(17-21-7)16-13(18)15-9-5-8(14)10(19-2)6-11(9)20-3/h4-6H,1-3H3,(H2,15,16,17,18)

InChI key: InChIKey=CEIIEALEIHQDBX-UHFFFAOYSA-N

SMILES: N(C(NC1=NOC(C)=C1)=O)C2=C(OC)C=C(OC)C(Cl)=C2

Synonyms:

• 1-(5-Chloro-2,4-dimethoxy-phenyl)-3-(5-methyl-isoxazol-3-yl)-urea
• N-(5-Chloro-2,4-Dimethoxyphenyl)-N'-(5-Methyl-3-Isoxazolyl)-Urea
• NSC 216666
• Pnu 120596
• Urea, N-(5-chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-
• 1-(5-Chloro-2,4-dimethoxyphenyl)-3-(5-methyl-1,2-oxazol-3-yl)urea

N-(5-CHLORO-2,4-DIMETHOXYPHENYL)-N'-(5-METHYL-3-ISOXAZOLYL)-UREA

CAS: 501925-31-1

Formula: C₁₃H₁₄ClN₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 311.7210

Ref: IN-DA00DABH

PNU-120596

CAS: 501925-31-1

PNU-120596

Purity: ≥98%

Molecular weight: 311.72g/mol

Ref: 54-BUP10606

PNU-120596

CAS: 501925-31-1

Formula: C₁₃H₁₄ClN₃O₄

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 311.72

Ref: 7W-GL0662

1-(5-Chloro-2,4-Dimethoxyphenyl)-3-(5-Methylisoxazol-3-Yl)Urea

CAS: 501925-31-1

1-(5-Chloro-2,4-Dimethoxyphenyl)-3-(5-Methylisoxazol-3-Yl)Urea

Purity: 99+%

Molecular weight: 311.72g/mol

Ref: 54-OR1023882

PNU-120596

CAS: 501925-31-1

PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.

Formula: C₁₃H₁₄ClN₃O₄

Purity: 99.82%

Color and Shape: Solid

Molecular weight: 311.72

Ref: TM-T6950

PNU 120596

CAS: 501925-31-1

A type-II positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors with IC50 values of 216 nM. Increases calcium flux in response to agonists, by lengthening the channel’s mean open time. Ex vivo and in vivo models of ischemic stroke demonstrate the conversion of endogenous choline or acetylcholine into neuroprotective agents by PNU 120596.

Formula: C₁₃H₁₄ClN₃O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 311.72 g/mol

Ref: 3D-BP162686

1-(5-Chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea

CAS: 501925-31-1

Formula: C₁₃H₁₄ClN₃O₄

Purity: 98%

Molecular weight: 311.72

Ref: 10-F215712