1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid is a chemical compound characterized by its indazole core, which is a five-membered heterocyclic structure containing two nitrogen atoms. The presence of a 4-fluorobenzyl group enhances its lipophilicity and may influence its biological activity. This compound features a carboxylic acid functional group, which contributes to its acidity and potential for forming salts or esters. It is often studied in medicinal chemistry for its potential pharmacological properties, including anti-inflammatory and analgesic effects. The fluorine atom in the benzyl group can modulate the compound's electronic properties and steric hindrance, impacting its interaction with biological targets. Additionally, the compound's solubility, stability, and reactivity can be influenced by the presence of the carboxylic acid and the fluorobenzyl substituent. As with many indazole derivatives, it may exhibit interesting properties in drug development and research applications. Safety and handling precautions should be observed, as with all chemical substances, due to potential toxicity or reactivity.

AB-FUBINACA metabolite 4 (Item No. 20179) is an analytical reference standard that is structurally classified as a synthetic cannabinoid. It is the carboxylic acid indazole 4-fluorobenzyl metabolite of AB-FUBINACA (Item Nos.
14039
|
ISO60211
). The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.

1-(4-fluorobenzyl)-1H-indazole-3-carboxylic acid

50264-63-6: 1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid is a chemical compound characterized by its indazole core, which is a five-membered heterocyclic structure containing two nitrogen atoms. The presence of a 4-fluorobenzyl group enhances its lipophilicity and may influence its biological activity. This compound features a carboxylic acid functional group, which contributes to its acidity and potential for forming salts or esters. It is often studied in medicinal chemistry for its potential pharmacological properties, including anti-inflammatory and analgesic effects. The fluorine atom in the benzyl group can modulate the compound's electronic properties and steric hindrance, impacting its interaction with biological targets. Additionally, the compound's solubility, stability, and reactivity can be influenced by the presence of the carboxylic acid and the fluorobenzyl substituent. As with many indazole derivatives, it may exhibit interesting properties in drug development and research applications. Safety and handling precautions should be observed, as with all chemical substances, due to potential toxicity or reactivity.

1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid (Compound 31) is a metabolite of AB-FUBINACA. It acts as an MRGPRX4 antagonist with an IC50 greater than 2.5 μM.

1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid

1-[(4-Fluorophenyl)methyl]-1H-indazole-3-carboxylic acid

CAS 50264-63-6

1-(4-fluorobenzyl)-1H-indazole-3-carboxylic acid

1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid

Ref: TM-T203147

1-[(4-Fluorophenyl)methyl]-1H-indazole-3-carboxylic acid

Ref: 54-PC200018