CAS 50264-69-2

lonidamine

Description:

Lonidamine is a chemical compound classified as an anti-cancer agent, primarily used in the treatment of various tumors. It is known for its ability to inhibit tumor growth by interfering with cellular metabolism and promoting apoptosis in cancer cells. The substance has a molecular formula that reflects its complex structure, which includes multiple functional groups that contribute to its biological activity. Lonidamine exhibits moderate solubility in organic solvents and limited solubility in water, which can influence its bioavailability and therapeutic efficacy. Its mechanism of action involves the inhibition of mitochondrial respiration and glycolysis, leading to reduced energy production in rapidly dividing cancer cells. Additionally, lonidamine has been studied for its potential effects on other conditions, including male infertility, due to its influence on sperm motility. As with many pharmacological agents, the use of lonidamine may be associated with side effects, and its clinical application is typically guided by careful consideration of the patient's specific condition and overall treatment plan.

Formula: C₁₅H₁₀Cl₂N₂O₂

InChI: InChI=1/C15H10Cl2N2O2/c16-10-6-5-9(12(17)7-10)8-19-13-4-2-1-3-11(13)14(18-19)15(20)21/h1-7H,8H2,(H,20,21)

InChI key: InChIKey=WDRYRZXSPDWGEB-UHFFFAOYSA-N

SMILES: C(N1C=2C(C(C(O)=O)=N1)=CC=CC2)C3=C(Cl)C=C(Cl)C=C3

Synonyms:

• 1-((2,4-Dichlorophenyl)Methyl)-1H-Indazole-3-Carboxylicacid
• 1-(2,4-Dichlorbenzyl)-Indazole-3-Carboxylicacid
• 1-(2,4-Dichlorobenzyl)-1H-Indazole-3-Carboxylicacid
• 1-(2,4-Dichlorobenzyl)indazole-3-carboxylic acid
• 1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxylic acid
• 1-(3,4-dichlorobenzyl)-1H-indazole-3-carboxylic acid
• 1-[(2,4-Dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid
• 1-[(2,4-Dichlorophenyl)methyl]indazole-3-carboxylic acid
• 1H-Indazole-3-carboxylic acid, 1-[(2,4-dichlorophenyl)methyl]-
• Af 1890
• Af1890
• Dica
• Diclondazolic Acid
• Doridamina
• LONIDAMINE
• 1-(2,4-dichlorobenzyl)-1h-indazole-3-carboxylicaci
• lonidamin
• 1-[(2，4-Dichloropheny1) methyl]-1H-indazole-3-carboxylic acid
• AF-1890：DICA
• 1-[（2,4-Dichlorophenyl）methyl]-1H-indazole-3-carboxylic acid, DICA
• 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid, Diclondazolic acid
• 1-((2,4-dichlorophenyl)methyl)-1h-indazole-3-carboxylicaci
• 13iclondazolic Acid

Lonidamine

CAS: 50264-69-2

Formula: C₁₅H₁₀Cl₂N₂O₂

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 321.16

Ref: 3B-L0283

1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid

CAS: 50264-69-2

Formula: C₁₅H₁₀Cl₂N₂O₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 321.1581

Ref: IN-DA0037DL

Lonidamine

CAS: 50264-69-2

Lonidamine (Diclondazolic Acid) is an indazole carboxylic acid derivative, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-

Formula: C₁₅H₁₀Cl₂N₂O₂

Purity: 97.90%

Color and Shape: White To Light Yellow Crystal

Molecular weight: 321.16

Ref: TM-T0239

Lonidamine

CAS: 50264-69-2

Lonidamine

Purity: ≥95%

Molecular weight: 321.16g/mol

Ref: 54-BUP11907

Lonidamine

CAS: 50264-69-2

Lonidamine

Purity: 99%

Molecular weight: 321.16g/mol

Ref: 54-BIL0844

Lonidamine

CAS: 50264-69-2

Formula: C₁₅H₁₀Cl₂N₂O₂

Molecular weight: 321.16

Ref: 7W-GP2670

Lonidamine

Controlled Product

CAS: 50264-69-2

Inactivates hexokinase; inhibits glycolysis; antispermatogenic; antineoplastic

Formula: C₁₅H₁₀Cl₂N₂O₂

Color and Shape: Yellow Powder

Molecular weight: 321.16 g/mol

Ref: 3D-FL32739

1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid

CAS: 50264-69-2

Formula: C₁₅H₁₀Cl₂N₂O₂

Purity: 99%

Color and Shape: No data available.

Molecular weight: 321.16

Ref: 10-F079516

Lonidamine

Controlled Product

CAS: 50264-69-2

Applications Lonidamine

Formula: C₁₅H₁₀Cl₂N₂O₂

Color and Shape: White To Off-White

Molecular weight: 321.16

Ref: TR-L469458