CAS 50264-69-2: lonidamine

Description: Lonidamine is a chemical compound classified as an anti-cancer agent, primarily used in the treatment of various tumors. It is known for its ability to inhibit tumor growth by interfering with cellular metabolism and promoting apoptosis in cancer cells. The substance has a molecular formula that reflects its complex structure, which includes multiple functional groups that contribute to its biological activity. Lonidamine exhibits moderate solubility in organic solvents and limited solubility in water, which can influence its bioavailability and therapeutic efficacy. Its mechanism of action involves the inhibition of mitochondrial respiration and glycolysis, leading to reduced energy production in rapidly dividing cancer cells. Additionally, lonidamine has been studied for its potential effects on other conditions, including male infertility, due to its influence on sperm motility. As with many pharmacological agents, the use of lonidamine may be associated with side effects, and its clinical application is typically guided by careful consideration of the patient's specific condition and overall treatment plan.

Formula: C₁₅H₁₀Cl₂N₂O₂

InChI: InChI=1S/C15H10Cl2N2O2/c16-10-6-5-9(12(17)7-10)8-19-13-4-2-1-3-11(13)14(18-19)15(20)21/h1-7H,8H2,(H,20,21)

InChI key: InChIKey=WDRYRZXSPDWGEB-UHFFFAOYSA-N

SMILES: O=C(O)C1=NN(C=2C=CC=CC12)CC3=CC=C(Cl)C=C3Cl

Synonyms:

• 1-((2,4-Dichlorophenyl)Methyl)-1H-Indazole-3-Carboxylicacid
• 1-(2,4-Dichlorbenzyl)-Indazole-3-Carboxylicacid
• 1-(2,4-Dichlorobenzyl)-1H-Indazole-3-Carboxylicacid
• 1-(2,4-Dichlorobenzyl)indazole-3-carboxylic acid
• 1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxylic acid
• 1-(3,4-dichlorobenzyl)-1H-indazole-3-carboxylic acid
• 1-[(2,4-Dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid
• 1-[(2,4-Dichlorophenyl)methyl]indazole-3-carboxylic acid
• 1H-Indazole-3-carboxylic acid, 1-[(2,4-dichlorophenyl)methyl]-
• Af 1890
• Af1890
• Dica
• Diclondazolic Acid
• Doridamina

Lonidamine

CAS: 50264-69-2

• Formula: C₁₅H₁₀Cl₂N₂O₂
• Purity: >95.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 321.16

1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid

CAS: 50264-69-2

• Formula: C₁₅H₁₀Cl₂N₂O₂
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 321.1581

Lonidamine

CAS: 50264-69-2

Lonidamine (Diclondazolic Acid) is an indazole carboxylic acid derivative, principally inhibiting aerobic glycolytic activity, by …

• Formula: C₁₅H₁₀Cl₂N₂O₂
• Purity: 97.90%
• Color and Shape: White To Light Yellow Crystal
• Molecular weight: 321.16

Lonidamine

CAS: 50264-69-2

• Purity: 97.36%
• Molecular weight: 321.16g/mol

Lonidamine

CAS: 50264-69-2

• Molecular weight: 321.16g/mol

Lonidamine

CAS: 50264-69-2

• Formula: C₁₅H₁₀Cl₂N₂O₂
• Molecular weight: 321.16

1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid

CAS: 50264-69-2

• Purity: 95.0%
• Color and Shape: Liquid, No data available.
• Molecular weight: 321.1600036621094

Lonidamine

CAS: 50264-69-2

Inactivates hexokinase; inhibits glycolysis; antispermatogenic; antineoplastic

• Formula: C₁₅H₁₀Cl₂N₂O₂
• Color and Shape: Yellow Powder
• Molecular weight: 321.16 g/mol

Lonidamine

CAS: 50264-69-2

Applications Lonidamine

• Formula: C₁₅H₁₀Cl₂N₂O₂
• Color and Shape: White To Off-White
• Molecular weight: 321.16