CAS 503-87-7

Thiohydantoin

Description:

Thiohydantoin, with the CAS number 503-87-7, is a heterocyclic organic compound characterized by its five-membered ring structure containing both sulfur and nitrogen atoms. It is a derivative of hydantoin, where the oxygen atom is replaced by a sulfur atom, resulting in a thioamide functional group. Thiohydantoin is typically a white to off-white crystalline solid, and it is soluble in polar solvents such as water and alcohols. This compound exhibits interesting chemical reactivity, particularly in the formation of thiourea derivatives and other sulfur-containing compounds. Thiohydantoin is often studied for its potential applications in medicinal chemistry, particularly as a scaffold for the development of pharmaceuticals due to its biological activity. Additionally, it can serve as a reagent in organic synthesis, facilitating various chemical transformations. Its stability and reactivity make it a valuable compound in both research and industrial applications. However, as with many chemical substances, proper handling and safety precautions are essential due to potential toxicity and reactivity.

Formula: C₃H₄N₂OS

InChI: InChI=1S/C3H4N2OS/c6-2-1-4-3(7)5-2/h1H2,(H2,4,5,6,7)

InChI key: InChIKey=UGWULZWUXSCWPX-UHFFFAOYSA-N

SMILES: O=C1NC(=S)NC1

Synonyms:

• 2-Sulfanylideneimidazolidin-4-one
• 2-Thioguidanthion
• 2-Thioxo-4-imidazolidinone
• 2-Thioxoimidazolidin-4-One
• 4-Imidazolidinone, 2-thioxo-
• 4-Oxo-2-thioxoimidazolidine
• Ai3-61106
• Brn 0110599
• Hydantoin, 2-thio-
• Imidazolidin-4-one-2-thione
• Nsc 11772
• Thiohydantoin
• Usaf Be-25

2-Thiohydantoin

CAS: 503-87-7

Formula: C₃H₄N₂OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 116.1417

Ref: IN-DA003HY4

2-Thioxoimidazolidin-4-one

CAS: 503-87-7

2-Thioxoimidazolidin-4-one

Purity: 98%

Color and Shape: Solid

Molecular weight: 116.14g/mol

Ref: 54-OR49042

2-Thiohydantoin

CAS: 503-87-7

2-Thiohydantoin is an organic compound that has been structurally characterized. The molecule is planar with a shape that can be described as a chair with both arms. It has been shown to have some interesting biological properties, including the ability to inhibit bowel disease and cancerous growths. 2-Thiohydantoin was also found to be an effective inhibitor of the mitochondrial membrane potential in rats and mice, suggesting it may work by inhibiting mitochondria. 2-Thiohydantoin has also been shown to increase the formation of hydrogen fluoride and other reactive oxygen species, which may contribute to its anti-bacterial activity.

Formula: C₃H₄N₂OS

Purity: (%) Min. 98%

Color and Shape: Powder

Molecular weight: 116.14 g/mol

Ref: 3D-FT06177

2-Thiohydantoin

CAS: 503-87-7

Formula: C₃H₄N₂OS

Purity: 98%

Molecular weight: 116.14

Ref: 10-F069068

2-Thiohydantoin

Controlled Product

CAS: 503-87-7

Applications 2-Thiohydantoin is a useful synthetic intermediate. It is a reactant for synthesis of drugs with antidiabetic activity, barbituric acid and thiohydantoin derivatives with antimicrobial activity, and possible anticancer agents.
References Ceylan-Ünlüsoy, M., et al.: J. Enzyme. Inhib. Med. Chem., 25, 784 (2010); Hassanein, M., et al: Mol. Human Reprod., 15, 433 (2009); Subtel’na, I., et al.: Bioorg. Med. Chem., 18, 5090 (2010)

Formula: C₃H₄N₂OS

Color and Shape: Neat

Molecular weight: 116.14

Ref: TR-T344490