CAS 503468-95-9

8-(dibenzo[b,d]thiophen-4-yl)-2-(morpholin-4-yl)-4H-chromen-4-one

Description:

The chemical substance known as 8-(dibenzo[b,d]thiophen-4-yl)-2-(morpholin-4-yl)-4H-chromen-4-one, with the CAS number 503468-95-9, is a synthetic organic compound characterized by its complex structure, which includes a chromenone core, a dibenzo[b,d]thiophene moiety, and a morpholine substituent. This compound typically exhibits properties such as fluorescence and potential biological activity, making it of interest in medicinal chemistry and materials science. Its structure suggests it may interact with various biological targets, potentially leading to applications in drug development. The presence of the morpholine ring can enhance solubility and bioavailability, while the dibenzo[b,d]thiophene unit may contribute to its electronic properties. Additionally, the chromenone framework is known for its versatility in organic synthesis and its role in various chemical reactions. Overall, this compound represents a unique combination of structural features that may confer interesting chemical and biological properties, warranting further investigation for potential applications in pharmaceuticals or as a fluorescent probe.

Formula: C₂₅H₁₉NO₃S

InChI: InChI=1/C25H19NO3S/c27-21-15-23(26-11-13-28-14-12-26)29-24-17(6-3-9-20(21)24)19-8-4-7-18-16-5-1-2-10-22(16)30-25(18)19/h1-10,15H,11-14H2

SMILES: c1ccc2c(c1)c1cccc(c3cccc4c(=O)cc(N5CCOCC5)oc34)c1s2

Synonyms:

• 8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-one
• Nu7441
• Ku 57788

NU7441 (KU-57788)

CAS: 503468-95-9

Formula: C₂₅H₁₉NO₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 413.4883

Ref: IN-DA00D811

KU-57788

CAS: 503468-95-9

KU-57788

Purity: 98%

Molecular weight: 413.49g/mol

Ref: 54-OR1024396

KU-57788

CAS: 503468-95-9

KU-57788

Purity: ≥98%

Molecular weight: 413.49g/mol

Ref: 54-BUP05853

KU-57788

CAS: 503468-95-9

NU7441 (KU-57788 (NU7441)) is a highly effective and specific DNA-PK inhibitor (IC50: 14 nM).

Formula: C₂₅H₁₉NO₃S

Purity: 98% - >99.99%

Color and Shape: Solid

Molecular weight: 413.49

Ref: TM-T6276

NU 7441

Controlled Product

CAS: 503468-95-9

Applications A potent novel DNA-dependent protein kinase inhibitor models of human cancer. Antitumor agent.
References Caldecott, K., et al.: Cancer Res., 50, 5778 (1990), Boulton, S., et al.: Eur. J. Cancer, 36, 535 (2000), Jackson, S., et al.: Carcinogenesis, 23, 687 (2002), Sandler, A., et al.: Semin. Oncol., 30, 9 (2003), Hardcastle, I., et al.: J. Med. Chem., 48, 7829 (2005),

Formula: C₂₅H₁₉NO₃S

Color and Shape: Neat

Molecular weight: 413.49

Ref: TR-N925300