CAS 503555-55-3

PHA-408

CAS: 503555-55-3

PHA-408 is a novel potent, highly selective and ATP-competitive inhibitor of IKB kinase-2.

Formula: C₂₉H₂₇ClFN₇O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 560.02

Ref: TM-T24629

PHA 408

CAS: 503555-55-3

PHA 408 is a natural compound that has inhibitory properties against chronic exposure of the bowel to inflammatory substances. It was shown to have a significant effect in animal models for autoimmune diseases, including Crohn's disease and ulcerative colitis. PHA 408 inhibits the production of pro-inflammatory cytokines by inhibiting the activation of NF-κB and AP-1. PHA 408 also inhibits the production of inflammatory prostaglandins and nitric oxide (NO). This drug has been shown to be effective in vivo treatment for inflammatory bowel disease.

Formula: C₂₉H₂₇ClFN₇O₂

Purity: Min. 95%

Molecular weight: 560.02 g/mol

Ref: 3D-DVA55555