CAS 50358-63-9

6-Amino-5-bromoquinoxaline

Description:

6-Amino-5-bromoquinoxaline is a heterocyclic organic compound characterized by its quinoxaline structure, which consists of a fused benzene and pyrazine ring. This compound features an amino group (-NH2) at the 6-position and a bromo substituent at the 5-position of the quinoxaline ring, contributing to its reactivity and potential biological activity. It is typically a solid at room temperature and may exhibit moderate solubility in polar solvents. The presence of the amino group allows for hydrogen bonding, which can influence its interactions in biological systems. 6-Amino-5-bromoquinoxaline has garnered interest in medicinal chemistry due to its potential applications in drug development, particularly in the field of cancer research and as a scaffold for synthesizing various bioactive compounds. Its chemical properties, such as reactivity and stability, can be influenced by the presence of the bromine atom, which can participate in electrophilic substitution reactions. Overall, this compound represents a valuable structure for further exploration in pharmaceutical chemistry.

Formula: C₈H₆BrN₃

InChI: InChI=1/C8H6BrN3/c9-7-5(10)1-2-6-8(7)12-4-3-11-6/h1-4H,10H2

InChI key: InChIKey=IRAOSCSPAYZRJE-UHFFFAOYSA-N

SMILES: BrC=1C2=C(C=CC1N)N=CC=N2

Synonyms:

• 5-Bromo-6-Amino Quinoxaline
• 5-Bromo-6-aminoquinoxaline
• 5-Bromo-6-quinoxalinamine
• 5-Bromoquinoxalin-6-Amine
• 6-Quinoxalinamine, 5-bromo-
• 6-Amino-5-bromoquinoxaline
• 6-Amino-5-bromoquinoxaline 98%
• 6-Amino-5-bromoquinoxaline ,98%

Brimonidine Related Compound A (5-Bromoquinoxalin-6-amine)

CAS: 50358-63-9

Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi

Formula: C₈H₆BrN₃

Color and Shape: Yellow Crystalline Powder

Molecular weight: 222.97451

Ref: 45-1076419

5-Bromoquinoxalin-6-amine

CAS: 50358-63-9

Formula: C₈H₆BrN₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 224.0573

Ref: IN-DA00348K

6-Amino-5-bromoquinoxaline

CAS: 50358-63-9

Compound PDK0245, with CAS No. 50358-63-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0245 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Formula: C₈H₆BrN₃

Molecular weight: 224.05

Ref: TM-PDK0245

Brimonidine EP Impurity B (Brimonidine USP Related Compound A)

CAS: 50358-63-9

Formula: C₈H₆BrN₃

Color and Shape: Brown Solid

Molecular weight: 224.06

Ref: 4Z-B-1610

5-Bromoquinoxalin-6-amine

CAS: 50358-63-9

Color and Shape: Neat

Ref: 86-MM1324.02

6-Amino-5-bromoquinoxaline

CAS: 50358-63-9

Formula: C₈H₆BrN₃

Purity: >98.0%(GC)(T)

Color and Shape: Light yellow to Amber to Dark green powder to crystal

Molecular weight: 224.06

Ref: 3B-A2913

6-Amino-5-bromoquinoxaline

CAS: 50358-63-9

6-Amino-5-bromoquinoxaline

Purity: 98%

Molecular weight: 224.06g/mol

Ref: 54-OR30436

6-Amino-5-bromoquinoxaline

CAS: 50358-63-9

Impurity Brimonidine EP Impurity B
Applications A metabolite of Brimonidine.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jeon, Y. T., et al.: Bioorg. Med. Chem. Lett., 5, 2255 (1995),

Formula: C₈H₆BrN₃

Color and Shape: Yellow

Molecular weight: 224.06

Ref: TR-A601885

Brimonidine EP Impurity B

CAS: 50358-63-9

Formula: C₈H₆BrN₃

Molecular weight: 224.06

Ref: ST-EA-CP-B16002

6-Amino-5-bromoquinoxaline

CAS: 50358-63-9

6-Amino-5-bromoquinoxaline is an inhibitor of serine proteases that has been shown to be effective in cell culture and in wild-type mice. It inhibits the enzyme by binding to the catalytic site, blocking the formation of a covalent bond between polypeptide chain and amino acid substrate. 6-Amino-5-bromoquinoxaline has also been shown to have an inhibitory effect on fibrinogen and polyclonal antibodies and can be used as a buffer for other proteases. In addition, this compound also inhibits caproic acid production from fatty acids via an unknown mechanism.br>
6-Amino-5-bromoquinoxaline is not active against synthetic substrates or monoclonal antibodies.

Formula: C₈H₆BrN₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 224.05 g/mol

Ref: 3D-FA10517

5-Bromoquinoxalin-6-amine

CAS: 50358-63-9

Formula: C₈H₆BrN₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 224.061

Ref: 10-F067517