CAS 50394-89-3
:17-ethynylestra-1(10),2,4-triene-2,3,17-triol
Description:
17-Ethynylestra-1(10),2,4-triene-2,3,17-triol, commonly known as a synthetic estrogen, is a chemical compound characterized by its complex steroid structure, which includes an ethynyl group and multiple hydroxyl (-OH) functional groups. This compound is derived from the steroid backbone of estradiol, modified to enhance its oral bioavailability and potency. It exhibits strong estrogenic activity, making it useful in various pharmaceutical applications, particularly in hormonal contraceptives and hormone replacement therapies. The presence of the ethynyl group at the 17 position contributes to its stability and resistance to metabolic degradation. Additionally, the triene configuration in the steroid nucleus allows for specific interactions with estrogen receptors, influencing gene expression and physiological responses related to female reproductive health. As with many synthetic hormones, its use is associated with both therapeutic benefits and potential side effects, necessitating careful consideration in clinical applications.
Formula:C20H24O3
InChI:InChI=1/C20H24O3/c1-3-20(23)9-7-16-14-5-4-12-10-17(21)18(22)11-15(12)13(14)6-8-19(16,20)2/h1,10-11,13-14,16,21-23H,4-9H2,2H3/t13-,14+,16-,19-,20?/m0/s1
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Found 3 products.
2-Hydroxy Ethynyl Estradiol
CAS:Controlled ProductFormula:C20H24O3Color and Shape:NeatMolecular weight:312.402-Hydroxy ethynyl estradiol
CAS:<p>2-Hydroxy ethynyl estradiol is a synthetic estrogen that has been used in animal studies to study the effects of estrogens on the brain. It is active as an antiestrogen at high doses and has been shown to be a potent inhibitor of brain norepinephrine uptake. 2-Hydroxy ethynyl estradiol has been used as a marker for cytochrome P450 enzymes and NADPH-cytochrome P450 reductase in rat brain. This compound also binds to estrogen receptors in women, although it does not have any biological activity due to its lack of a 17β-hydroxyl group. The drug has also been shown to inhibit noradrenergic neurons in the central nervous system.</p>Formula:C20H24O3Purity:Min. 95%Molecular weight:312.4 g/mol
