CAS 50402-56-7

EDANS

Description:

EDANS, or 5-((2-aminoethyl)amino)naphthalene-1-sulfonic acid, is a fluorescent dye commonly used in biochemistry and molecular biology for labeling and detecting biomolecules. It features a naphthalene core, which contributes to its fluorescent properties, and an aminoethyl side chain that enhances its solubility in aqueous solutions. EDANS exhibits strong fluorescence upon excitation, making it valuable in various applications, including fluorescence resonance energy transfer (FRET) assays, where it can serve as a donor fluorophore. The sulfonic acid group improves its water solubility and stability in biological environments. EDANS is often paired with other fluorophores to create FRET pairs, allowing researchers to study molecular interactions and dynamics in real-time. Its characteristics include high quantum yield, good photostability, and compatibility with a range of biological systems, making it a versatile tool in fluorescence-based assays and imaging techniques. However, as with any chemical substance, proper handling and safety precautions should be observed due to potential toxicity and reactivity.

Formula: C₁₂H₁₄N₂O₃S

InChI: InChI=1S/C12H14N2O3S/c13-7-8-14-11-5-1-4-10-9(11)3-2-6-12(10)18(15,16)17/h1-6,14H,7-8,13H2,(H,15,16,17)

InChI key: InChIKey=SJQRQOKXQKVJGJ-UHFFFAOYSA-N

SMILES: N(CCN)C=1C2=C(C(S(=O)(=O)O)=CC=C2)C=CC1

Synonyms:

• 1-Naphthalenesulfonic acid, 5-[(2-aminoethyl)amino]-
• EDANS
• 1,5-EDANS
• 5-[(2-Aminoethyl)amino]-1-naphthalenesulfonic acid

5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid

CAS: 50402-56-7

Formula: C₁₂H₁₄N₂O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 266.3162

Ref: IN-DA003SDY

Phenylethyl b-D-thioglucuronide

CAS: 50402-56-7

Ref: 7W-GC2383

5-[(2-Aminoethyl)amino]naphthalene-1-sulphonic acid

CAS: 50402-56-7

5-[(2-Aminoethyl)amino]naphthalene-1-sulphonic acid

Purity: 95%

Color and Shape: Solid

Molecular weight: 266.32g/mol

Ref: 54-OR0920T

EDANS

CAS: 50402-56-7

EDANS

Purity: ≥98%

Molecular weight: 266.32g/mol

Ref: 54-BUP14632

EDANS

CAS: 50402-56-7

EDANS (EDANS acid [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid]) is a novel and quenched fluorogenic substrate for assaying retroviral protease by

Formula: C₁₂H₁₄N₂O₃S

Purity: 99.73%

Color and Shape: Gray-Yellow Crystalline Powder

Molecular weight: 266.32

Ref: TM-TD0081

N-(Aminoethyl)-5-naphthylamine-1-sulfonic Acid

Controlled Product

CAS: 50402-56-7

Applications A fluorescent reagent with a terminal amine for derivatization. 1,5-EDANS has similar spectral properties to the naphthalenesulfonic acids. Fluorescence: max. Abs. 335nm; max. Em. 493nm; e x 10-3: 5.9
References Warfield, R., et al.: Org. Biomol. Chem., 4, 3626 (2006), Elston, C., et al.: Anal. Biochem., 368, 87 (2007),

Formula: C₁₂H₁₄N₂O₃S

Color and Shape: Neat

Molecular weight: 266.32

Ref: TR-A609200

N-(Aminoethyl)-5-naphthylamine-1-sulfonic acid

CAS: 50402-56-7

The Michaelis-Menten kinetics of N-(Aminoethyl)-5-naphthylamine-1-sulfonic acid (NENSA) have been determined by studying the reaction of NENSA with a variety of acceptors. Basic fibroblasts were found to be a good substrate for this compound and it was shown that proteolytic activity is required for the hydrolysis of NENSA. The toxin is also reactive with the enzyme polymerase chain, which inhibits bacterial growth. In the presence of epidermal growth factor, NENSA has been shown to inhibit proliferation in fetal bovine retinal cells and human epidermal keratinocytes.

Formula: C₁₂H₁₄N₂O₃S

Purity: Min. 97 Area-%

Color and Shape: Yellow Powder

Molecular weight: 266.32 g/mol

Ref: 3D-FA76568

5-(2-Aminoethylamino)-1-Naphthalene Sulfonic Acid(1,5-EDANS)

CAS: 50402-56-7

Formula: C₁₂H₁₄N₂O₃S

Purity: 95%

Molecular weight: 266.32

Ref: 10-M03636

5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid

CAS: 50402-56-7

Purity: 98%

Molecular weight: 266.3200073

Ref: 10-F862840