CAS 50444-03-6

(5alpha,6alpha)-3-methoxy-7,8-didehydro-4,5-epoxymorphinan-6-yl beta-D-glucopyranosiduronic acid

Description:

The chemical substance known as (5alpha,6alpha)-3-methoxy-7,8-didehydro-4,5-epoxymorphinan-6-yl beta-D-glucopyranosiduronic acid, with the CAS number 50444-03-6, is a complex organic compound that belongs to the class of morphinans, which are derivatives of morphine. This compound features a morphinan backbone, characterized by a fused ring system that includes a phenanthrene structure. The presence of a methoxy group and an epoxide contributes to its unique reactivity and potential biological activity. The beta-D-glucopyranosiduronic acid moiety indicates that it has a sugar component, which may enhance its solubility and influence its pharmacokinetic properties. Such compounds are often studied for their potential therapeutic effects, particularly in the context of analgesia or as modulators of opioid receptors. The specific stereochemistry, indicated by the 5alpha and 6alpha designations, plays a crucial role in determining the compound's interaction with biological targets. Overall, this substance represents a significant area of interest in medicinal chemistry and pharmacology.

Formula: C₂₃H₂₇NO₉

InChI: InChI=1/C23H27NO9/c1-30-12-4-2-9-8-11-10-3-5-13(20-23(10,6-7-24-11)14(9)18(12)32-20)31-22-17(27)15(25)16(26)19(33-22)21(28)29/h2-5,10-11,13,15-17,19-20,22,24-27H,6-8H2,1H3,(H,28,29)/t10?,11?,13-,15-,16-,17+,19-,20-,22+,23?/m0/s1

Norcodeine O-β-D-Glucuronid

Controlled Product

CAS: 50444-03-6

Applications Norcodeine O-β-D-Glucuronide is the glucuronide conjugate of Norcodeine (N661605) and metabolite of Codeine (C634080).
References He, H. et al.: J. Chrom B Biomed. Sci. Appl., 708, 185 (1998); Svensson, J.O. et al.: J. Chrom B Biomed. Sci. Appl., 674, 49 (1995);

Formula: C₂₃H₂₇NO₉

Color and Shape: Neat

Molecular weight: 461.462

Ref: TR-N661605