CAS 5053-08-7

Fenspiride hydrochloride

Description:

Fenspiride hydrochloride is a pharmaceutical compound primarily used as an antitussive and anti-inflammatory agent. It is classified as a non-opioid cough suppressant and is often utilized in the treatment of respiratory conditions characterized by cough and inflammation, such as bronchitis and asthma. The substance is known for its ability to modulate the cough reflex without the sedative effects commonly associated with opioid cough suppressants. Fenspiride hydrochloride exhibits a moderate solubility in water and is typically administered in oral form. Its mechanism of action involves the inhibition of certain inflammatory mediators, contributing to its therapeutic effects. The compound has a relatively low toxicity profile, making it suitable for use in various patient populations. As with any medication, potential side effects may include gastrointestinal disturbances or allergic reactions, and it is essential to use it under medical supervision. Overall, Fenspiride hydrochloride represents a valuable option in the management of cough and related respiratory symptoms.

Formula: C₁₅H₂₀N₂O₂·ClH

InChI: InChI=1S/C15H20N2O2.ClH/c18-14-16-12-15(19-14)7-10-17(11-8-15)9-6-13-4-2-1-3-5-13;/h1-5H,6-12H2,(H,16,18);1H

InChI key: InChIKey=FIKFLLIUPUVONI-UHFFFAOYSA-N

SMILES: O=C1OC2(CCN(CCC3=CC=CC=C3)CC2)CN1.Cl

Synonyms:

• 1-Oxa-3,8-diazaspiro(4,5)decan-2-one, 8-(2-phenylethyl)-, monohydrochloride
• 1-Oxa-3,8-diazaspiro(4.5)decan-2-one, 8-(2-phenylethyl)-, monohydrochloride
• 1-Oxa-3,8-diazaspiro(4.5)decan-2-one, 8-phenethyl-, monohydrochloride
• 1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 8-(2-phenylethyl)-, hydrochloride (1:1)
• 2-Oxazolidinone-5-Spiro-4'-[N-(2-Phenylethyl)Piperidine] Hydrochloride
• 8-(2-Phenylethyl)-1-Oxa-3,8-Diazaspiro[4.5]Decan-2-One Hydrochloride (1:1)
• 8-(2-Phenylethyl)-1-oxa-3,8-diazaspiro(4.5)decan-2-one hydrochloride
• 8-N-Fenetil-1-oxa-2-oxo-3,8-diazaspiro-(4,5)-decano cloridrato
• 8-N-Fenetil-1-oxa-2-oxo-3,8-diazaspiro-(4,5)-decano cloridrato [Italian]
• 8-Phenethyl-1-oxa-3,8-diazaspiro(4.5)decan-2-one monohydrochloride
• 8-Phenethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride
• Chlorhydrate de phenethyl-8-oxa-1-diaza-3,8-spiro(4,5)decanone-2
• Chlorhydrate de phenethyl-8-oxa-1-diaza-3,8-spiro(4,5)decanone-2 [French]
• Decaspir
• Decaspiride
• Erespal
• Espiran
• Fenspiride HCl
• Fluiden
• Jp 428
• Nat-333
• Ndr-5998A
• Phenethyl-8-oxa-1-diaza-3,8-spiro(4,5)decanone-2-hydrochloride
• Pneumorel
• Tegencia
• Tegencia hydrochloride
• Unii-832Nbx878V
• Viarespan
• Viarespan hydrochloride

Fenspiride Hydrochloride

CAS: 5053-06-5, 5053-08-7

Formula: C₁₅H₂₀N₂O₂·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 296.80

Ref: 3B-F1211

Fenspiride hydrochloride

CAS: 5053-08-7

Fenspiride HCl treats respiratory diseases including asthma and ENT inflammation in Russia.

Formula: C₁₅H₂₀N₂O₂·HCl

Purity: 99.64% - 99.92%

Color and Shape: Solid

Molecular weight: 296.79

Ref: TM-T0383

2-OXAZOLIDINONE-5-SPIRO-4'-[N-(2-PHENYLETHYL)PIPERIDINE] HYDROCHLORIDE

CAS: 5053-08-7

Formula: C₁₅H₂₁ClN₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 296.7924

Ref: IN-DA00DEIW

Fenspiride hydrochloride

CAS: 5053-08-7

Fenspiride hydrochloride

Purity: ≥98%

Molecular weight: 296.79g/mol

Ref: 54-BUP14802

Fenspiride Hydrochloride

CAS: 5053-08-7

Fenspiride Hydrochloride

Purity: 98%

Molecular weight: 296.79g/mol

Ref: 54-OR1030362

Fenspiride hydrochloride

CAS: 5053-08-7

Formula: C₁₅H₂₀N₂O₂·HCl

Purity: ≥ 98.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 296.79

Ref: 7W-GP7005

Fenspiride Hydrochloride

CAS: 5053-08-7

Color and Shape: Neat

Ref: 86-MM3773.00

Fenspiride hydrochloride

CAS: 5053-08-7

Formula: C₁₅H₂₀N₂O₂·ClH

Color and Shape: Neat

Molecular weight: 296.79

Ref: 04-C13565000

Fenspiride HCl

CAS: 5053-08-7

Formula: C₁₅H₂₀N₂O₂·HCl

Molecular weight: 260.34 36.46

Ref: 4Z-F-293

Fenspiride hydrochloride

CAS: 5053-08-7

Fenspiride HCl is a fine chemical that can be used as a reagent, speciality chemical, and research chemical. It is also a versatile building block and reaction component. Fenspiride HCl is an intermediate in the synthesis of complex compounds and has been reported to have multiple uses.

Formula: C₁₅H₂₀N₂O₂•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 296.79 g/mol

Ref: 3D-FF23269

Fenspiride Hydrochloride

Controlled Product

CAS: 5053-08-7

Applications Bronchodilator with anti-inflammatory properties. Inhibits mucus secretion and reduces the release of tachykinins at a prejunctional level by its anti-muscarinic action. It also may be an antagonist at α adrenergic and H1 histamine receptors.
References LeDouarec, et al.: Arzneim.-Forsch., 19, 1263 (1969), Lho, D., et al.: J. Anal. Toxicol., 14, 73 (1990), Dallakian, P., et al.: J. Anal. Toxicol., 20, 255 (1996),

Formula: C₁₅H₂₀N₂O₂·ClH

Color and Shape: Neat

Molecular weight: 296.79

Ref: TR-F265000