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CAS 50567-35-6

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Methamizole

Description:
Methamizole, also known as metamizole or dipyrone, is a non-opioid analgesic and antipyretic agent. It is commonly used to relieve pain and reduce fever. Methamizole is characterized by its ability to inhibit prostaglandin synthesis, which contributes to its analgesic and antipyretic effects. The substance is typically administered in its sodium salt form, enhancing its solubility in water. Methamizole is known for its rapid onset of action and is often utilized in clinical settings for acute pain management. However, its use is restricted or banned in some countries due to concerns about potential side effects, particularly agranulocytosis, a serious condition that can lead to a dangerously low white blood cell count. The compound is generally well-tolerated when used appropriately, but monitoring for adverse effects is essential. Methamizole is classified under the category of pyrazolones and has a molecular formula that reflects its complex structure, contributing to its pharmacological properties.
Formula:C13H17N3O4S
InChI:InChI=1S/C13H17N3O4S/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11/h4-8H,9H2,1-3H3,(H,18,19,20)
InChI key:InChIKey=LVWZTYCIRDMTEY-UHFFFAOYSA-N
SMILES:O=C1N(N(C)C(C)=C1N(CS(=O)(=O)O)C)C2=CC=CC=C2
Synonyms:
  • (Antipyrinylmethylamino)methanesulfonic acid
  • 1-[(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonic acid
  • Melubrin, methyl-
  • Metamizol
  • Metamizolum
  • Methamizole
  • Methanesulfonic acid, (antipyrinylmethylamino)-
  • Methanesulfonic acid, 1-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]-
  • Methanesulfonic acid, [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]-
  • N-Methyl-N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)aminomethanesulfosaeure
  • See more synonyms
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