CAS 50650-76-5: Piroctone

Description: Piroctone, with the CAS number 50650-76-5, is an antifungal agent commonly used in dermatological and cosmetic formulations, particularly in shampoos and topical treatments for dandruff and seborrheic dermatitis. It is known for its ability to inhibit the growth of fungi, particularly Malassezia species, which are often implicated in scalp conditions. Piroctone is characterized by its broad-spectrum antifungal activity, low toxicity, and good skin compatibility, making it suitable for use in various personal care products. The compound is typically presented as a white to off-white powder and is soluble in organic solvents, but has limited solubility in water. Its mechanism of action involves disrupting the fungal cell membrane, leading to cell death. Additionally, Piroctone has been noted for its conditioning properties, which can enhance the overall feel and appearance of hair when included in formulations. Overall, Piroctone is valued for its efficacy and safety profile in treating fungal-related skin conditions.

Formula: C₁₄H₂₃NO₂

InChI: InChI=1S/C14H23NO2/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5/h6,8,11,17H,7,9H2,1-5H3

InChI key: InChIKey=OIQJEQLSYJSNDS-UHFFFAOYSA-N

SMILES: O=C1C=C(C=C(N1O)CC(C)CC(C)(C)C)C

Synonyms:

• 1-Hydroxy-4-methyl-6(2,4,4-trimethylpentyl)-2-pyridone
• 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridinone
• 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone
• 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one
• 2(1H)-pyridinone, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-
• Piroctonol
• Piroctone

Piroctone Olamine

CAS: 50650-76-568890-66-4

• Formula: C₁₄H₂₃NO₂·C₂H₇NO
• Purity: >97.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 298.43