CAS 50673-97-7

Colestolone

Description:

Colestolone, with the CAS number 50673-97-7, is a synthetic steroid compound that is structurally related to cholesterol. It is characterized by its steroidal framework, which consists of four fused carbon rings. Colestolone is primarily recognized for its role in research related to cholesterol metabolism and its potential applications in pharmacology. The compound exhibits lipophilic properties, allowing it to interact with lipid membranes and influence various biological processes. It is often studied for its effects on lipid profiles and its potential therapeutic implications in conditions related to cholesterol dysregulation. Additionally, colestolone may serve as a precursor or intermediate in the synthesis of other steroid derivatives. Its solubility characteristics, stability under physiological conditions, and specific interactions with biological receptors are key areas of interest in ongoing research. As with many steroid compounds, safety and toxicity profiles are essential considerations in its application and study.

Formula: C₂₇H₄₄O₂

InChI: InChI=1/C27H44O2/c1-17(2)7-6-8-18(3)23-16-24(29)25-21-10-9-19-15-20(28)11-13-26(19,4)22(21)12-14-27(23,25)5/h17-20,22-23,28H,6-16H2,1-5H3/t18-,19+,20+,22+,23-,26+,27-/m1/s1

InChI key: InChIKey=LINVVMHRTUSXHL-GGVPDPBRSA-N

SMILES: C[C@@]12C(=C3[C@@]([C@]4(C)[C@@](CC3)(C[C@@H](O)CC4)[H])(CC1)[H])C(=O)C[C@@]2([C@@H](CCCC(C)C)C)[H]

Synonyms:

• (3Beta,5Alpha)-3-Hydroxycholest-8(14)-En-15-One
• (3S,5S,10S,13R,17R)-17-(1,5-dimethylhexyl)-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,9,11,12,16,17-dodecahydrocyclopenta[a]phenanthren-15-one
• (3β,5α)-3-Hydroxycholest-8(14)-en-15-one
• 3-Hydroxycholest-8(14)-En-15-One
• 3beta-Hydroxy-5alpha-cholest-8(14)-en-15-one
• 3β-Hydroxy-5α-cholest-8(14)-en-15-one
• 5α-Cholest-8(14)-en-3β-ol-15-one
• Cholest-8(14)-en-15-one, 3-hydroxy-, (3beta,5alpha)-
• Cholest-8(14)-en-15-one, 3-hydroxy-, (3β,5α)-
• Cholest-8(14)-en-3-ol-15-one
• Cl 274,471
• Colestolona
• Colestolona [INN-Spanish]
• Colestolone [USAN:INN]
• Colestolonum
• Colestolonum [INN-Latin]
• Unii-5P8396T5Xf
• Colestolone
• 15-ketocholestene
• 3-HYDROXY-5Α-CHOLEST-8(14)-EN-15-ONE;15-KETOCHOLESTENE
• 15-Ketosterol
• 17-(1,5-Dimethylhexyl)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,9,10,11,12,13,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-15-one
• 3-Hydroxy-5Α-Cholest-8(14)-En-15-One
• 17-(1,5-DIMETHYLHEXYL)-3-HYDROXY-10,13-DIMETHYL-2,3,4,5,6,7,9,10,11,12,13,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-15-ONE
• 17-(1,5-Dimethylhexyl)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,9,10,11,12,13,15,16,17-tetradecahydro-1H-cyclopenta[a]phenan
• 3-hydroxy-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,7,10,11,12,13,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-15(9H)-one

Colestolone

CAS: 50673-97-7

Formula: C₂₇H₄₄O₂

Molecular weight: 400.6371

Ref: IN-DA00D9NC

15-Ketocholestene

Controlled Product

CAS: 50673-97-7

15-Ketocholestene is a natural product that inhibits the synthesis of cholesterol by binding to cholesterol esterase, preventing the breakdown of fatty acids. It has been shown to have an inhibitory effect on liver cells, which may be due to its ability to inhibit sodium-dependent glucose uptake. 15-Ketocholestene has also been shown to reduce blood and liver cholesterol levels in Sprague-Dawley rats. The mechanism of action is not fully understood, but it has been speculated that this inhibition may be due to an alkylthio group or a carbonyl group. 15-Ketocholestene has also been shown to have anti-hepatitis effects.

Formula: C₂₇H₄₄O₂

Purity: Min. 95%

Molecular weight: 400.6 g/mol

Ref: 3D-ACA67397