CAS 50700-72-6

Vecuronium

Description:

Vecuronium is a non-depolarizing neuromuscular blocking agent commonly used in anesthesia to facilitate intubation and provide muscle relaxation during surgical procedures. It acts by competitively inhibiting the action of acetylcholine at the neuromuscular junction, thereby preventing muscle contraction. Vecuronium is characterized by its intermediate duration of action, making it suitable for both short and long surgical procedures. It is typically administered intravenously and is metabolized primarily in the liver, with some excretion occurring via the kidneys. The onset of action is relatively rapid, allowing for quick muscle relaxation. Vecuronium is often preferred due to its minimal cardiovascular effects compared to other neuromuscular blockers. Its chemical structure includes a steroid backbone, which contributes to its pharmacological properties. As with all neuromuscular blockers, careful monitoring of neuromuscular function is essential during its use to avoid complications such as prolonged paralysis or respiratory insufficiency.

Formula: C₃₄H₅₇BrN₂O₄

InChI: InChI=1/C34H57N2O4.BrH/c1-23(37)39-31-20-25-12-13-26-27(34(25,4)22-29(31)35-16-8-6-9-17-35)14-15-33(3)28(26)21-30(32(33)40-24(2)38)36(5)18-10-7-11-19-36;/h25-32H,6-22H2,1-5H3;1H/q+1;/p-1/t25?,26?,27?,28?,29-,30-,31-,32-,33-,34-;/m0./s1

InChI key: InChIKey=VEPSYABRBFXYIB-PWXDFCLTSA-M

SMILES: C[C@@]12[C@]([C@]3([C@](CC1)([C@]4(C)[C@@](CC3)(C[C@H](OC(C)=O)[C@H](C4)N5CCCCC5)[H])[H])[H])(C[C@@H]([C@@H]2OC(C)=O)[N@@+]6(C)CCCCC6)[H].[Br-]

Synonyms:

• Androstane, piperidinium deriv.
• Bromure De Vecuronium
• Bromuro De Vecuronio
• Musculax
• Nc 45
• Norcuron
• Org-NC 45
• Piperidinium, 1-[(2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-, bromide (1:1)
• Vecuronium
• Vecuronium Bromide
• Vecuroniumbromid
• (2beta,3alpha,8xi,9xi,14xi,16beta,17beta)-3,17-bis(acetyloxy)-16-(1-methylpiperidinium-1-yl)-2-piperidin-1-ylandrostane bromide
• (+)-1-(3,17-Diacetoxy-2-piperidino-5-androstan-16-yl)-1-methylpiperidinium bromide
• Piperidinium, 1-[(2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-, bromide
• (2beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetyloxy)-16-(1-methylpiperidinium-1-yl)-2-(piperidin-1-yl)androstane
• (3alpha,5alpha)-3,17-bis(acetyloxy)-16-(1-methylpiperidinium-1-yl)-2-piperidin-1-ylandrostane bromide
• VECURONIUM BROMIDE, USP STANDARD
• VENCURONIUM BROMIDE
• VECURONIUM BROMIDE, EP
• VECRONIUM BROMIDE
• 1-(3-alpha,17-beta-diacetoxy-2-beta-piperidino-5-alpha-androstan-piperidiniu
• VECURUNIUM BROMIDE
• Piperidinium, 1-[(2,3α,5α ,16,17)-3,17-bis(acetyloxy)-2-(1-piperidinyl )androstan-16-yl]-1-methyl-, bromide
• 17beta-diol,16beta-pipecolinio-2beta-piperidino-5alpha-androstan-3alphbro
• Piperidinium, 1-[(2b,3a,5a,16b,17b)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-, bromide (9CI)
• mide,diacetate
• orgnc45
• VECURONIUM BROMIDE, RELATED COMPOUND A3ALPHA, 17BETA-DIACETYL-OXY-2BETA, 16BETA-BISPIPERIDINYL-5ALPHA-ANDROSTAN USP STANDARD

Vecuronium Bromide

CAS: 50700-72-6

Formula: C₃₄H₅₇BrN₂O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 637.74

Ref: 3B-V0120

VECURONIUM BROMIDE CRS

CAS: 50700-72-6

VECURONIUM BROMIDE CRS

Formula: C₃₄H₅₇BrN₂O₄

Color and Shape: Added Modified

Molecular weight: 637.7314

Ref: 41-Y0000561

VECURONIUM FOR SYSTEM SUITABILITY CRS

CAS: 50700-72-6

VECURONIUM FOR SYSTEM SUITABILITY CRS

Formula: C₃₄H₅₇BrN₂O₄

Color and Shape: Crystalline Powder. Crystals. White. Powder.

Molecular weight: 637.7314

Ref: 41-Y0001862

Vecuronium bromide

CAS: 50700-72-6

Vecuronium bromide

Formula: C₃₄H₅₇BrN₂O₄

Purity: 96.5%

Color and Shape: White

Molecular weight: 636.35017

Ref: 47-1167

Vecuronium Bromide

CAS: 50700-72-6

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₃₄H₅₇BrN₂O₄

Color and Shape: White Off-White Powder

Molecular weight: 636.35017

Ref: 45-1711155

1-[(2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium bromide hydrate

CAS: 50700-72-6

Formula: C₃₄H₅₇BrN₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 637.7314

Ref: IN-DA006WE4

Vecuronium bromide

CAS: 50700-72-6

Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscle

Formula: C₃₄H₅₇BrN₂O₄

Purity: 99.63% - 99.92%

Color and Shape: White Powder

Molecular weight: 637.73

Ref: TM-T1594

Vecuronium bromide

CAS: 50700-72-6

Vecuronium bromide

Purity: 98%

Molecular weight: 637.73g/mol

Ref: 54-OR1030225

Vecuronium bromide

CAS: 50700-72-6

Formula: C₃₄H₅₇BrN₂O₄

Purity: (HPLC) ≥ 99.0%

Color and Shape: White to off-white powder

Molecular weight: 637.73

Ref: 7W-GP9070

Vecuronium Bromide

CAS: 50700-72-6

Formula: C₃₄H₅₇N₂O₄·Br

Color and Shape: White To Off-White Solid

Molecular weight: 557.84 79.90

Ref: 4Z-V-069001

Vecuronium bromide

CAS: 50700-72-6

Vecuronium bromide

Purity: ≥98%

Molecular weight: 637.73g/mol

Ref: 54-BUP13705

Vecuronium Bromide

Controlled Product

CAS: 50700-72-6

Formula: C₃₄H₅₇N₂O₄·Br

Color and Shape: White

Molecular weight: 637.73

Ref: 86-MM1620.00

Vecuronium Bromide

CAS: 50700-72-6

Stability Hygroscopic
Applications An aminosteroid, competitive neuromuscular blocker agent.
References Buckett, W.R., et al.: J. Med. Chem., 16, 1116 (1973), Fahey, M.R., et al.: Anesthesiology, 55, 6 (1981), Gibb, A., et al.: Br. J. Pharmacol., 89, 619 (1986), Blount, K., et al.: Toxicon., 30, 835 (1992),

Formula: C₃₄H₅₇N₂O₄·Br

Color and Shape: Neat

Molecular weight: 637.73

Ref: TR-V102500

Vecuronium bromide

CAS: 50700-72-6

Antagonist of nicotinic acetylcholine receptors; nondepolarising muscle relaxant

Formula: C₃₄H₅₇BrN₂O₄

Purity: Min. 95%

Molecular weight: 637.73 g/mol

Ref: 3D-FV61481

Vecuronium bromide

CAS: 50700-72-6

Purity: ≥99%

Molecular weight: 637.7440186

Ref: 10-F863083