CAS 50704-43-3

6-(trideuteriomethoxy)-7H-purin-2-amine

Description:

6-(Trideuteriomethoxy)-7H-purin-2-amine, with the CAS number 50704-43-3, is a deuterated derivative of purine, a fundamental building block of nucleic acids. This compound features a methoxy group (-OCH3) that is fully deuterated, meaning that the hydrogen atoms in the methoxy group are replaced with deuterium, a stable isotope of hydrogen. The presence of deuterium can significantly alter the physical and chemical properties of the compound, such as its stability, solubility, and reactivity, compared to its non-deuterated counterparts. This substance is primarily used in research applications, particularly in studies involving metabolic pathways, drug development, and tracer studies in biological systems. Its unique isotopic labeling allows for enhanced detection and analysis using techniques like nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry. Overall, 6-(trideuteriomethoxy)-7H-purin-2-amine serves as a valuable tool in the field of biochemistry and pharmacology.

Formula: C₆H₄D₃N₅O

InChI: InChI=1/C6H7N5O/c1-12-5-3-4(9-2-8-3)10-6(7)11-5/h2H,1H3,(H3,7,8,9,10,11)/i1D3

SMILES: C(Oc1c2c([nH]cn2)[nH]c(=N)n1)([2H])([2H])[2H]

6-O-Methyl-d3-guanine

CAS: 50704-43-3

Molecular weight: 168.17

Ref: 7W-GP9126

6-O-Methyl-d3-guanine

Controlled Product

CAS: 50704-43-3

Applications Antitumor agent.
References Morse, M., et al.: Cancer Res., 50, 2613 (1990), Staretz, M., et al.: Carcinogenesis, 18, 1715 (1997), Henderson, C., et al.: J. Biol. Chem., 278, 13480 (2003), Jalas, J., et al.: Chem. Res. Toxicol., 16, 794 (2003), Su, T., et al.: Toxicol. Appl. Pharmacol., 199, 285 (2004),

Formula: C₆₂H₃H₄N₅O

Color and Shape: White Solid

Molecular weight: 168.17

Ref: TR-M311802