CAS 508-54-3

Hydroxycodeinone

Description:

Hydroxycodeinone, with the CAS number 508-54-3, is an opioid analgesic that is derived from codeine. It is characterized by its chemical structure, which includes a hydroxyl group and a ketone functional group, contributing to its pharmacological properties. Hydroxycodeinone exhibits analgesic effects, making it useful in pain management, though it is less potent than its parent compound, morphine. The substance is typically encountered in a crystalline form and is soluble in organic solvents, but its solubility in water is limited. As an opioid, it acts primarily on the central nervous system by binding to opioid receptors, leading to effects such as pain relief, sedation, and potential euphoria. However, like other opioids, it carries risks of dependence, tolerance, and potential for abuse. Due to its pharmacological profile, hydroxycodeinone is subject to regulatory controls in many countries, and its use is often restricted to specific medical contexts. Proper handling and prescription are essential to mitigate risks associated with its use.

Formula: C₁₈H₁₉NO₄

InChI: InChI=1S/C18H19NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-6,13,16,21H,7-9H2,1-2H3/t13-,16+,17+,18-/m1/s1

InChI key: InChIKey=YYCRAERBSFHMPL-XFKAJCMBSA-N

SMILES: O[C@]12[C@@]34C=5C(O[C@]3(C(=O)C=C1)[H])=C(OC)C=CC5C[C@]2(N(C)CC4)[H]

Synonyms:

• (5Alpha)-14-Hydroxy-3-Methoxy-17-Methyl-7,8-Didehydro-4,5-Epoxymorphinan-6-One
• (5alpha)-7,8-Didehydro-4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
• 14-Hydroxy-3-Methoxy-17-Methyl-7,8-Didehydro-4,5-Epoxymorphinan-6-One
• 14-Hydroxycodeinone
• 14β-Hydroxycodeinone
• Brn 4552573
• Codeinone, 14-hydroxy-
• Hydroxycodeinone
• Morphinan-6-one, 7,8-didehydro-4,5-epoxy-14-hydroxy-3-methoxy-17-methyl-, (5-alpha)- (9CI)
• Morphinan-6-one, 7,8-didehydro-4,5-epoxy-14-hydroxy-3-methoxy-17-methyl-, (5α)-
• Morphinan-6-one, 7,8-didehydro-4,5α-epoxy-14-hydroxy-3-methoxy-17-methyl-

OXYCODONE IMPURITY D CRS

CAS: 508-54-3

OXYCODONE IMPURITY D CRS

Formula: C₁₈H₁₉NO₄

Color and Shape: Powder

Molecular weight: 313.3478

Ref: 41-Y0000453

7,8-Didehydro-4,5α-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one (14-Hydroxycodeinone)

Controlled Product

CAS: 508-54-3

Color and Shape: Neat

Ref: 86-MM0672.04

14-Hydroxy Codeinone

Controlled Product

CAS: 508-54-3

Applications An intermediate in the preparation of Oxycodone and other alkaloid based opiate antagonists.
References Brogle, K., et al.: J. Pharm. Biomed. Anal., 19, 669 (1999), Szentesi, A., et al.: Anal. Bioanal. Chem., 374, 427 (2002), Lattanzi, R., et al.: J. Med. Chem., 48, 3372 (2005),

Formula: C₁₈H₁₉NO₄

Color and Shape: White To Grey

Molecular weight: 313.35

Ref: TR-H922200

Oxycodone Related Compound A CII (14-hydroxycodeinone)

Controlled Product

CAS: 508-54-3

Alkaloids of opium and their derivatives, salts thereof

Formula: C₁₈H₁₉NO₄

Color and Shape: White Powder

Molecular weight: 313.13141

Ref: 45-1485216