CAS 508-75-8: Convallatoxin

Description:Convallatoxin is a toxic cardiac glycoside derived from the plant Convallaria majalis, commonly known as lily of the valley. It is characterized by its ability to inhibit the Na+/K+ ATPase enzyme, which plays a crucial role in maintaining the electrochemical gradient across cell membranes. This inhibition leads to increased intracellular sodium levels, subsequently causing an increase in intracellular calcium concentrations, which can enhance cardiac contractility. Convallatoxin exhibits a structure typical of cardiac glycosides, featuring a steroid nucleus with a sugar moiety. Its pharmacological effects can lead to symptoms of toxicity, including nausea, vomiting, and potentially life-threatening arrhythmias. Due to its potent biological activity, convallatoxin has been studied for its potential therapeutic applications, although its narrow therapeutic window necessitates caution. Handling this compound requires appropriate safety measures due to its toxic nature, and it is classified as a hazardous substance. Overall, convallatoxin exemplifies the complex interplay between natural products and pharmacology, highlighting both its potential benefits and risks.

Formula:C₂₉H₄₂O₁₀

InChI:InChI=1S/C29H42O10/c1-15-22(32)23(33)24(34)25(38-15)39-17-3-8-27(14-30)19-4-7-26(2)18(16-11-21(31)37-13-16)6-10-29(26,36)20(19)5-9-28(27,35)12-17/h11,14-15,17-20,22-25,32-36H,3-10,12-13H2,1-2H3/t15-,17-,18+,19-,20+,22-,23+,24+,25-,26+,27-,28-,29-/m0/s1

InChI key:InChIKey=HULMNSIAKWANQO-JQKSAQOKSA-N

SMILES:O=CC12CCC(OC3OC(C)C(O)C(O)C3O)CC2(O)CCC4C1CCC5(C)C(C6=CC(=O)OC6)CCC45O

Synonyms:
(3beta,5beta)-3-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxocard-20(22)-enolide
(3beta,5beta,17xi)-3-[(6-deoxy-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxocard-20(22)-enolide
(3beta,5beta,8xi,9xi)-3-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxocard-20(22)-enolide
(3β,5β)-3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxocard-20(22)-enolide
3-[(6-Deoxyhexopyranosyl)Oxy]-5,14-Dihydroxy-19-Oxocard-20(22)-Enolide
3beta-((6-Deoxy-alpha-L-mannopyranosyl)oxy)-5,14-dihydroxy-19-oxo-5beta-card-20(22)-enolide
Card-20(22)-enolide, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-5,14-dihydroxy-19-oxo-, (3beta,5beta)-
Card-20(22)-enolide, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-5,14-dihydroxy-19-oxo-, (3beta,5beta)- (9CI)
Card-20(22)-enolide, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxo-, (3β,5β)-
Convallaotoxin
See more synonyms
Convallaton
Convallatoxine
Convallatoxoside
Convallotoxin
Corglycon
Corglycone
Corglykon
Hsdb 3475
Korglykon
Mannopyranoside, strophanthidin-3,6-deoxy-, alpha-L-
Nsc 407808
Rhamnoside, strophanthidin-3, alpha-L-
Strophanthidin alpha-L-rhamnoside
Strophanthidin α-L-rhamnoside
Strophanthidin, 3-(6-deoxy-alpha-L-mannopyranoside)
(3β,5β)-3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxocard-20(22)-enolide
Convallatoxin
Card-20(22)-enolide, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxo-, (3β,5β)-

Found 7 products.

Product data	Purity	Price range	Estimated delivery
Convallatoxin REF: 7W-GY9874CAS: 508-75-8	- - -	To inquire	Mon 21 Apr 25
Convallatoxin REF: 54-BUP00478CAS: 508-75-8	99.27%	1,041.00 €~1,350.00 €	Mon 21 Apr 25
Convallatoxin REF: BP-BP0389CAS: 508-75-8	95%~99%	133.00 €~680.00 €	Tue 22 Apr 25
Convallatoxin REF: TM-TN1525CAS: 508-75-8	99.27%	130.00 €~998.00 €	Thu 24 Apr 25
Convallatoxin REF: 5G-80834CAS: 508-75-8	≥ 95.0 % (HPLC)	169.00 €~11,464.00 €	Mon 28 Apr 25
Convallatoxin REF: TR-C685075CAS: 508-75-8	- - -	110.00 €~357.00 €	Tue 29 Apr 25
Convallatoxin REF: 3D-FC137904CAS: 508-75-8	Min. 95%	To inquire	Thu 29 May 25