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CAS 508-99-6

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Hydrocortisone cypionate

Description:
Hydrocortisone cypionate is a synthetic corticosteroid, primarily used for its anti-inflammatory and immunosuppressive properties. It is a derivative of hydrocortisone, with a cypionate ester that enhances its pharmacokinetic profile, allowing for prolonged action in the body. This compound is typically administered via intramuscular injection and is utilized in various medical conditions, including adrenal insufficiency and certain inflammatory disorders. Hydrocortisone cypionate exhibits characteristics such as high solubility in organic solvents and moderate solubility in water, which influences its formulation and delivery. The substance acts by binding to glucocorticoid receptors, leading to a cascade of biological effects that modulate gene expression and cellular responses. Its use must be carefully monitored due to potential side effects, including suppression of the hypothalamic-pituitary-adrenal (HPA) axis and increased risk of infections. Overall, hydrocortisone cypionate is an important therapeutic agent in the management of conditions requiring corticosteroid intervention.
Formula:C29H42O6
InChI:InChI=1/C29H42O6/c1-27-13-11-20(30)15-19(27)8-9-21-22-12-14-29(34,28(22,2)16-23(31)26(21)27)24(32)17-35-25(33)10-7-18-5-3-4-6-18/h15,18,21-23,26,31,34H,3-14,16-17H2,1-2H3/t21-,22-,23-,26+,27-,28-,29-/m0/s1
InChI key:InChIKey=DLVOSEUFIRPIRM-KAQKJVHQSA-N
SMILES:C[C@@]12[C@]([C@]3([C@]([C@@H](O)C1)([C@]4(C)C(CC3)=CC(=O)CC4)[H])[H])(CC[C@@]2(C(COC(CCC5CCCC5)=O)=O)O)[H]
Synonyms:
  • (11Beta)-11,17-Dihydroxy-3,20-Dioxopregn-4-En-21-Yl 3-Cyclopentylpropanoate
  • (11β)-21-(3-Cyclopentyl-1-oxopropoxy)-11,17-dihydroxypregn-4-ene-3,20-dione
  • (8Xi,9Xi,10Xi,13Xi,14Xi)-11,17-Dihydroxy-3,20-Dioxopregn-4-En-21-Yl 3-Cyclopentylpropanoate
  • 11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21β-cyclopentanepropionate
  • 17-Hydroxycorticosterone 21β-cyclopentylpropionate
  • Cortef Oral Suspension
  • Cortisol cypionate
  • Cortisol, 21-cyclopentanepropionate
  • Cortisol, cyclopentanepropionate
  • Cyclopentanepropionic acid, 21-ester with cortisol
  • See more synonyms
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