CAS 50824-05-0

4-Trifluoromethoxybenzyl bromide

Description:

4-Trifluoromethoxybenzyl bromide is an organic compound characterized by the presence of a bromobenzyl group substituted with a trifluoromethoxy functional group. Its molecular structure features a benzene ring with a bromine atom and a trifluoromethoxy group (-O-CF3) attached to the para position. This compound is typically a colorless to pale yellow liquid or solid, depending on its purity and form. It is known for its reactivity, particularly in nucleophilic substitution reactions, due to the presence of the bromine atom, which can be displaced by various nucleophiles. The trifluoromethoxy group enhances the compound's lipophilicity and can influence its biological activity, making it of interest in medicinal chemistry and material science. Additionally, 4-Trifluoromethoxybenzyl bromide may exhibit unique physical and chemical properties, such as stability under certain conditions and solubility in organic solvents, which are important for its applications in synthesis and research. Safety precautions should be observed when handling this compound, as it may pose health risks.

Formula: C₈H₆BrF₃O

InChI: InChI=1S/C8H6BrF3O/c9-5-6-1-3-7(4-2-6)13-8(10,11)12/h1-4H,5H2

InChI key: InChIKey=JDNPUJCKXLOHOW-UHFFFAOYSA-N

SMILES: O(C(F)(F)F)C1=CC=C(CBr)C=C1

Synonyms:

• 1-(Bromomethyl)-4-(Trifluoromethoxy)Benzene
• 2-(Bromomethyl)-5-(trifluoromethoxy)benzene
• 4-(Bromomethyl)phenyl trifluoromethyl ether
• 4-(Trifluoromethoxy)-1-(bromomethyl)-benzene
• 4-(Trifluoromethoxy)benzyl
• 4-(Trifluoromethoxy)benzylbromide
• 4-Trifluoro methoxy benzyl bromide
• 4-Trifluoromethoxybenzyl bromide
• Alpha-Bromo-4-(Trifluoromethoxy)Toluene
• Benzene, 1-(bromomethyl)-4-(trifluoromethoxy)-
• P-TritluromethoxybenzylBromide
• Timtec-Bb Sbb006578
• [3,3,4,5,5,5-Hexafluoro-4-(Trifluoromethyl)Pentyl] Prop-2-Enoate

4-(Trifluoromethoxy)benzyl Bromide

CAS: 50824-05-0

Formula: C₈H₆BrF₃O

Purity: >98.0%(GC)

Color and Shape: White or Colorless to Light yellow powder to lump to clear liquid

Molecular weight: 255.03

Ref: 3B-T1781

4-(Trifluoromethoxy)benzyl bromide, 97%

CAS: 50824-05-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₆BrF₃O

Purity: 97%

Color and Shape: Clear colorless to yellow, Liquid

Molecular weight: 255.03

Ref: 02-A18335

4-(Trifluoromethoxy)benzyl bromide

CAS: 50824-05-0

Formula: C₈H₆BrF₃O

Purity: 98%

Color and Shape: Solid

Molecular weight: 255.0318

Ref: IN-DA0033U1

4-(Trifluoromethoxy)benzyl bromide

CAS: 50824-05-0

4-(Trifluoromethoxy)benzyl bromide

Formula: C₈H₆BrF₃O

Purity: 97%

Color and Shape: Low-Melting Solid

Molecular weight: 255.03g/mol

Ref: 54-PC7438UB

4-(Trifluoromethoxy)benzyl bromide

CAS: 50824-05-0

Formula: C₈H₆BrF₃O

Purity: 97%

Color and Shape: Liquid, Low Melting

Molecular weight: 255.034

Ref: 10-F008720

4-Trifluoromethoxybenzyl Bromide

Controlled Product

CAS: 50824-05-0

Applications 4-Trifluoromethoxybenzyl Bromide is a useful synthetic intermediate. It is used to prepare (nitro)[(trifluoromethoxy)benzyloxy]dihydroimidazo[2,1-b][1,3]oxazines with antitubercular activities. It is also used to synthesize tetrahydronaphthalenols with anti-allergic activities.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Li, X., et al.: Bioorg. Med. Chem. Lett., 18, 2256 (2008); Barlow, J., et al.: Eur. J. Med. Chem., 46, 1545 (2011)

Formula: C₈H₆BrF₃O

Color and Shape: Neat

Molecular weight: 255.03

Ref: TR-T774440